Preview

Health and Ecology Issues

Advanced search

APPLICATION OF SILVER IN MEDICINE: HISTORICAL ASPECTS AND MODERN VIEW ON THE PROBLEM

https://doi.org/10.51523/2708-6011.2011-8-3-30

Abstract

The literature review expounds the basic stages of the application of silver in medicine since the times of ancient civilizations up to date. Its most significant physicochemical properties have been described, the data on silver content in tissues of human body and Earth crust have been given, the modern view about the mechanism of the silver antimicrobial effect has been disclosed. The causes and types of the toxic reactions which are provoked by silver and its compounds in human have been analysed. The data on the danger of the excessive or uncontrolled silver application in medicine are given. The possible perspectives of the wider medical application of silver and its compounds are underlined in connection with the development of nanotechnologies.

About the Authors

R. I. Dovnar
Grodno State Medical University
Belarus


S. M. Smotrin
Grodno State Medical University
Belarus


References

1. Серебро в медицине / Е. М. Благитко [и др.]. - Новосибирск: Наука-Центр, 2004. - 256 с.

2. Seiler, H. G. Handbook on toxicity of inorganic compounds / H. G. Seiler, H. Sigel, A. Sigel. - New York: Marcel Dekker, 1987. - 1024 p.

3. Determination of silver in blood, urine, and tissues of volunteers and burn patients / A. T. Wan [et al.] // Clinical chemistry. - 1991. - Vol. 37, № 10. - P. 1683-1687.

4. Fox, C.L. Mechanism of silver sulfadiazine action on burn wound infections / C.L. Fox, S.M. Modak // Antimicrobial agents and chemotherapy. - 1974. - Vol. 5, №. 6. - Р. 582-588.

5. Melaiye, A. Silver and its application as an antimicrobial agent / A. Melaiye, W. J. Youngs // Expert opinion on therapeutic patents. - 2005. - Vol. 15, № 2. - P. 125-130.

6. Klasen, H. J. Historical review of the use of silver in the treatment of burns. I. Early uses / H. J. Klasen // Burns. - 2000. - Vol. 26, № 2. - P. 117-130.

7. Dousset, J. C. Histoire des medicaments / J. C. Dousset. - Paris: Payot, 1985. - 407 p.

8. Klasen, H. J. A historical review of the use of silver in the treatment of burns. II. Renewed interest for silver / H. J. Klasen // Burns. - 2000. - Vol. 26, № 2. - P. 131-138.

9. Treatment of large human burns with 0,5 % silver nitrate solution / C. A. Moyer [et al.] // Archives of surgery. - 1965. - Vol. 90, № 6. - P. 812-867.

10. Effect of silver on burn wound infection control and healing: review of the literature / B. S. Atiyeh [et al.] // Burns. - 2007. - Vol. 33, № 2. - P. 139-148.

11. Lansdown, A. B. Sequential changes in trace metal, metallothionein and calmodulin concentrations in healing skin wounds / A. B. Lansdown, B. Sampson, A. Rowe // Journal of anatomy. - 1999. - Vol. 195, № 3. - P. 375-386.

12. Burrell, R. E. A scientific perspective on the use of topical silver preparations / R. E. Burrell // Ostomy wound manage. - 2003. - Vol. 49, № 5. - P. 19-24.

13. Mooney, E. K. Silver dressings / E. K. Mooney, C. Lippitt, J. Friedman // Plastic and reconstructive surgery. - 2006. - Vol. 117, № 2. - P. 666-669.

14. Comparison of silver-coated dressing (Acticoat(TM)), chlorhexidine acetate 0,5 % (Bactigrass(TM)), and silver sulfadiazine 1 % (Silverdin(R)) for topical antibacterial effect in Pseudomonas aeruginosa-contaminated, full-skin thickness burn wounds in rats / E. Ulkur [et al.] // Journal of burn care and research. - 2005. - Vol. 26, № 5. - P. 430-433.

15. Silver-coated dressing acticoat caused raised liver enzymes and argyria-like symptoms in burn patient / M. Trop [et al.] // Journal of trauma-injury infection and critical care. - 2006. - Vol. 60, № 3. - P. 648-652.

16. Taylor, P. L. Impact of heat on nanocrystalline silver dressings. Part I. Chemical and biological properties / P. L. Taylor, A. L. Ussher, R. E. Burrell // Biomaterials. - 2005. - Vol. 26, № 35. - P. 7221-7229.

17. Gupta, A. Effects of halides on plasmid-mediated silver resistance in Escherichia coli / A. Gupta, M. Maynes, S. Silver // Applied and environmental microbiology. - 1998. - Vol. 64, № 12. - P. 5042-5045.

18. Lansdown, A. B. Silver 2: toxicity in mammals and how its products aid wound repair / A. B. Lansdown // Journal of wound care. - 2002. - Vol. 11, № 5. - P. 173-177.

19. Ballard, K. Avance: silver hydropolymer dressing for critically colonized wounds / K. Ballard, F. McGregor // British journal of nursing. - 2002. - Vol. 11, № 3. - P. 206-211.

20. Dunn, K. The role of Acticoat TM with nanocrystalline silver in the management of burns / K. Dunn, V. Edwards-Jones // Burns. - 2004. - Vol. 30. - P. 1-9.

21. Hendry, A. T. Silver-resistant Enterobacteriaceae from hospital patients / A. T. Hendry, I. O. Stewart // Canadian journal of microbiology. - 1979. - Vol. 25, № 8. - P. 915-921.

22. Maple, P. A. Comparison of the in-vitro activities of the topical antimicrobials azelaic acid nitroftnazone, silver sulphadiazine and mupirocin against methicillinresistant Staphylococcus aureus / P. A. Maple, J. M. Hamilton-Miller, W. Brumfitt // Journal of antimicrobial chemotherapy. - 1992. - Vol. 29, № 6. - P. 661-668.

23. Серебро - польза и вред / Э. Г. Акопова [и др.] // Кубанский научный медицинский вестник. - 2007. - № 1-2. - C. 8-11.

24. Fuller, F. W. Leukopenia in non-septic burn patients receiving topical 1 % silver sulphadiazine cream therapy: a survey / F. W. Fuller, P. E. Engler // Journal of burn care and research. - 1988. - Vol. 9, № 6. - P. 606-609.

25. Gamelli, R. L. Bone marrow toxicity by silver sulphadiazine / R. L. Gamelli, T. P. Paxton, M. O'Reilly // Surgery, gynecology and obstetrics. - 1993. - Vol. 177, № 2. - P. 115-120.

26. Greene, R. M. Argyria / R. M. Greene, W. P. Su // American family physician. - 1987. - Vol. 36, № 6. - P. 151-154.

27. Drake, P. L. Exposure-related health effects of silver and silver compounds: a review / P. L. Drake, K. J. Hazelwood // The annals of occupational hygiene. - 2005. - Vol. 49, № 7. - P. 575-585.

28. McCubbin, P. An in vitro analysis of the antimicrobial properties of 10 silver-containing dressings / P. McCubbin, S. Thomas // Journal of wound care. - 2003. - Vol. 12, № 8. - P. 305-308.

29. Array-based nano-amplification technique was applied in detection of hepatitis E virus / H. H. Liu [et al.] // Journal of biochemistry and molecular biology. - 2006. - Vol. 39, № 3. - P. 247-252.

30. Chen, X. Nanosilver: a nanoproduct in medical application / X. Chen, H. J. Schluesener // Toxicology letters. - 2008. - Vol. 176, № 1. - P. 1-12.


Review

For citations:


Dovnar R.I., Smotrin S.M. APPLICATION OF SILVER IN MEDICINE: HISTORICAL ASPECTS AND MODERN VIEW ON THE PROBLEM. Health and Ecology Issues. 2011;(3):149-153. (In Russ.) https://doi.org/10.51523/2708-6011.2011-8-3-30

Views: 443


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)