HUMAN PAPILLOMAVIRUS AS A RISK FACTOR OF THE DEVELOPMENT OF MALIGNANT PATHOLOGY UNDER PRETUMOR DISEASES OF HEAD AND NECK
https://doi.org/10.51523/2708-6011.2010-7-1s-24
Abstract
The complex assessment of the contribution of the virus constituent to the general picture of the malignant conversion of head and neck regions has revealed statistic significant figures which can be commensurable with those in the high risk group of patients suffering from cancer of larynx, differences (р ≤ 0,05) in the infection rate of HPV in comparison with the given index in the control group for the groups of patients with chronic diseases of tonsils and cancer of larynx. Various HPV types infecting epithelium of larynx were correlated with the stage of the malignant process: at stage III of the development of cancer of larynx a wider range was displayed in comparison with that in the patients with the disease stage II. The analysis of general and non-recurrent survival rate in HPV-positive and HPV-negative patients displayed increase of the terms of non-recurrent survival rate in the HPV-positive patients and absence of recurrence in the patients, positive for the HPV types HPV-16, 18, 31, 33.
About the Authors
O. Y. Shilova
Scientific Research Institute of Oncology of the Siberian Department of the Russian Academy of Medical Sciences
Belarus
Belarus
L. N. Urazova
Scientific Research Institute of Oncology of the Siberian Department of the Russian Academy of Medical Sciences
Belarus
Belarus
M. R. Muhamedov
Scientific Research Institute of Oncology of the Siberian Department of the Russian Academy of Medical Sciences
Belarus
Belarus
O. V. Cheremisina
Scientific Research Institute of Oncology of the Siberian Department of the Russian Academy of Medical Sciences
Belarus
Belarus
V. I. Yevtushenko
Scientific Research Institute of Oncology of the Siberian Department of the Russian Academy of Medical Sciences
Belarus
Belarus
E. L. Choynzonov
Scientific Research Institute of Oncology of the Siberian Department of the Russian Academy of Medical Sciences
Belarus
Belarus
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Review
For citations:
Shilova O.Y., Urazova L.N., Muhamedov M.R., Cheremisina O.V., Yevtushenko V.I., Choynzonov E.L. HUMAN PAPILLOMAVIRUS AS A RISK FACTOR OF THE DEVELOPMENT OF MALIGNANT PATHOLOGY UNDER PRETUMOR DISEASES OF HEAD AND NECK. Health and Ecology Issues. 2010;(1S):64-66. (In Russ.) https://doi.org/10.51523/2708-6011.2010-7-1s-24
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