ANTITUMORAL AND ANTIVIRAL EFFECTIVENESS OF PHOTODYNAMIC THERAPY IN PATIENTS WITH CERVICAL INTRAEPITHELIAL NEOPLASIA II-III SUFFERED FROM PHOTOLON
https://doi.org/10.51523/2708-6011.2010-7-1s-7
Abstract
The method of photodynamic therapy has been elaborated, studied experimentally and tested in a clinic in 112 patients with CIN II-III. The method of photodynamic therapy included two stages: administration of photosensybilizator фотосенсибилизатора and radiation treatment with a laser of long length, corresponding to the peak of the absorption of the medicine. The following theses were established: photodynamic therapy of CIN contributes to the decrease of the number of HPV-positive patients (from 81,2 to 56 %), the clinical effectiveness photodynamic therapy of CIN corresponds to 92,8 % of the completely recovered patients. Thus, the photodynamic therapy is an alternative treatment method with the preservation of the anatomic and functional integrity of the organ, which is important for women, who plan pregnancy. The results of a-5-year-monitoring of the patients with moderate and severe displasia and cancer in situ свидетельствуют о том, that the method of the photodynamic therapy, chosen regimens of the laser effect and light dose are adequate. The photodynamic therapy leads to the improvement of the prediction factors of the course of precancerous cervical diseases.
About the Authors
I. A. Kosenko
Republican Scientific Research Centre of Oncology and Medical Radiology named after N. N. Alexandrov
Belarus
Belarus
Y. P. Istomin
Republican Scientific Research Centre of Oncology and Medical Radiology named after N. N. Alexandrov
Belarus
Belarus
T. P. Laptsevich
Republican Scientific Research Centre of Oncology and Medical Radiology named after N. N. Alexandrov
Belarus
Belarus
V. N. Chalov
Republican Scientific Research Centre of Oncology and Medical Radiology named after N. N. Alexandrov
Belarus
Belarus
R. M. Smolyakova
Republican Scientific Research Centre of Oncology and Medical Radiology named after N. N. Alexandrov
Belarus
Belarus
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Review
For citations:
Kosenko I.A., Istomin Y.P., Laptsevich T.P., Chalov V.N., Smolyakova R.M. ANTITUMORAL AND ANTIVIRAL EFFECTIVENESS OF PHOTODYNAMIC THERAPY IN PATIENTS WITH CERVICAL INTRAEPITHELIAL NEOPLASIA II-III SUFFERED FROM PHOTOLON. Health and Ecology Issues. 2010;(1S):27-30. (In Russ.) https://doi.org/10.51523/2708-6011.2010-7-1s-7
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