Preview

Health and Ecology Issues

Advanced search

DETECTION AND QUANTITATIVE DETERMINATION OF WIDE HPV VARIETY IN REPRODUCTIVE WOMEN IN THE REGIONS OF SIBERIA

https://doi.org/10.51523/2708-6011.2010-7-1s-3

Abstract

A total of 419 women, citizens of Tomsk region, cities of Tyva and Saha (Yakutiya) took part in the investigation. The total number of HPV positive women in Tomsk region makes 56,6 %, in Tyva - 63,2 %, in Yakutiya region - 82,0 %. In the В the region of investigation, among HPV-positive women HPV-16 remains the most prevalent type (64,7 % - among the citizens of Tomsk region, 71,3 % - Tyva and 91,2 % - Yakutiya). During the investigation of virus load among HPV-positive women the clinically significant virus load (3-5 lg) is observed in the groups of patients with dysplasia and cervical carcinoma, whereas clinically insignificant HPV concentration (< 3 lg) predominates mainly in the groups of healthy women and women with cervical pathology. The influence of the regional peculiarities on the prevalence frequency and HPV spectrum was presented.

About the Authors

I. G. Vidyaeva
Scientific Research Centre of Oncology of the Siberian Department of the Russian Academy of Medical Sciences
Belarus


L. N. Urazova
Scientific Research Centre of Oncology of the Siberian Department of the Russian Academy of Medical Sciences
Belarus


L. F. Pisareva
Tyva Republican Oncologic Dispensary
Belarus


E. G. Nikitina
Tyva Republican Oncologic Dispensary
Belarus


G. N. Mansurova
Tyva Republican Oncologic Dispensary
Belarus


A. A. Shivit-Ool
Tyva Republican Oncologic Dispensary
Belarus


N. N. Makarova
Yakutiya Republican Oncologic Dispensary
Belarus


References

1. Евстигнеева, Н. П. Папилломавирусная инфекция урогенитального тракта женщин: эпидемиология, факторы персистенции, оптимизация ранней диагностики и профилактики онкогенеза: автореф. дис. … д-ра мед. наук / Н. П. Евстигнеева. - М., 2007. - 42 с.

2. Куевда, Д. А. ВПЧ-тестирование: алгоритмы диагностики и требования к молекулярным тестам для выявления вирусов папилломы человека / Д. А. Куевда, О. Ю. Шипулина // Генодиагностика инфекционных болезней - 2007: сб. тр. VI Всероссийской науч.-практ. конф. - 2007. - Т. 3. - С. 108-119.

3. Прилепская, В.Н. Профилактика рака шейки матки: методы ранней диагностики и новые скрининговые технологии / В. П. Прилепская // Гинекология. - 2007. - Т 9, № 1. - С. 12-14.

4. Epidemiologic classification of human papillomavirus types associated with cervical cancer / N. Muñoz [et al.] // N Engl J Med. - 2003. - Vol. 348. - P. 518-552.

5. For the American Cancer Society. American Cancer Society guideline for the early detection of cervical neoplasia and cancer. CA Cancer / D. Saslow [et al.] // J Clin. - 2002. - Vol. 52. - P. 342-362.

6. World Health Organization (WHO). Comprehensive Cervical Cancer Control: a guide to essential practice. Geneva: WHO, 1996.


Review

For citations:


Vidyaeva I.G., Urazova L.N., Pisareva L.F., Nikitina E.G., Mansurova G.N., Shivit-Ool A.A., Makarova N.N. DETECTION AND QUANTITATIVE DETERMINATION OF WIDE HPV VARIETY IN REPRODUCTIVE WOMEN IN THE REGIONS OF SIBERIA. Health and Ecology Issues. 2010;(1S):17-19. (In Russ.) https://doi.org/10.51523/2708-6011.2010-7-1s-3

Views: 260


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2220-0967 (Print)
ISSN 2708-6011 (Online)