FORECASTING OF INTERFERON THERAPY EFFICIENCY IN PATIENTS SUFFERING FROM CHRONIC HEPATITIS C WITH VARIOUS HCV GENOTYPES
https://doi.org/10.51523/2708-6011.2010-7-4-7
Abstract
The virologic response was evaluated in patients suffering from chronic hepatitis C with various hepatitis C virus (HCV) genotypes depending on detection frequency of antibodies to HCV NS5 protein and antibodies to HCV of IgM class, cytokines IFN-γ IL-2, IL-4, IL-1α, TNF-α serum levels in various terms of interferon therapy. The prognostic value of anti-NS5 negative test and anti-HCV IgM positive test, high levels of proinflammatory cytokine IL-1α and IL-4 for the assessment of the interferon therapy efficiency was shown.
About the Authors
E. L. Krasavtsev
Gomel State Medical University
Belarus
Belarus
V. M. Mitsura
Gomel State Medical University
Belarus
Belarus
A. P. Demchilo
Gomel State Medical University
Belarus
Belarus
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Review
For citations:
Krasavtsev E.L., Mitsura V.M., Demchilo A.P. FORECASTING OF INTERFERON THERAPY EFFICIENCY IN PATIENTS SUFFERING FROM CHRONIC HEPATITIS C WITH VARIOUS HCV GENOTYPES. Health and Ecology Issues. 2010;(4):39-43. (In Russ.) https://doi.org/10.51523/2708-6011.2010-7-4-7
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