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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2010-7-2-30</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-966</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НОВЫЕ ТЕХНОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEW TECHNOLOGIES</subject></subj-group></article-categories><title-group><article-title>НЕИНВАЗИВНАЯ ДИАГНОСТИКА КОЛОРЕКТАЛЬНОГО РАКА НА ОСНОВЕ ФЕКАЛЬНОГО ЛАКТОФЕРРИНА</article-title><trans-title-group xml:lang="en"><trans-title>FECAL LACTOFERRIN IN NON-INVASIVE DIAGNOSTIC OF COLORECTAL CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филипенко</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Filipenko</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2010</year></pub-date><volume>0</volume><issue>2</issue><fpage>143</fpage><lpage>148</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Филипенко Н.В., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Филипенко Н.В.</copyright-holder><copyright-holder xml:lang="en">Filipenko N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/966">https://journal.gsmu.by/jour/article/view/966</self-uri><abstract><p>Возможности выявления злокачественных опухолей толстой кишки были изучены у 48 пациентов с колоректальным раком, 47 - с синдромом раздраженного кишечника и 25 здоровых добровольцев методом комплексного сравнительного анализа. Установлено, что наиболее высокую диагностическую значимость имел фекальный лактоферрин (ППК: 0,95; 95 % ДИ: 0,89-0,98). Маркер обладал чувствительностью 79,17 % (95 % ДИ: 65,00-89,50), специфичностью - 90,14 % (95 % ДИ: 80,70-95,90)</p></abstract><trans-abstract xml:lang="en"><p>Possibilities of revealing of malignant tumours of a colon had been studied at 48 patients with colorectal cancer, 47 with irritable bowel syndrome and 25 healthy volunteers by the complex comparative analysis. It is established, that fecal lactoferrin had the highest diagnostic importance. (AUC: 0,95; 95 % CI: 0,89-0,98). The marker possessed sensitivity - 79,17 % (95 % CI: 65,00-89,50), specificity - 90,14 % (95 % CI: 80,70-95,90).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальный рак</kwd><kwd>неинвазивная диагностика</kwd><kwd>фекальный лактоферрин</kwd><kwd>иммуноферментный анализ</kwd><kwd>colorectal cancer</kwd><kwd>non-invasive diagnostic</kwd><kwd>fecal lactoferrin</kwd><kwd>immune-enzyme test</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Boyle, P. Epidemiology of colorectal cancer / Р. Boyle, M. E. Leon // Brit. Med. Bull. - 2002. - № 64. - P. 1-25.</mixed-citation><mixed-citation xml:lang="en">Boyle, P. Epidemiology of colorectal cancer / Р. Boyle, M. E. Leon // Brit. Med. 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