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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2010-7-1-29</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-932</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НОВЫЕ ТЕХНОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEW TECHNOLOGIES</subject></subj-group></article-categories><title-group><article-title>ПРЕПАРАТЫ РАСТОРОПШИ: НОВЫЕ ОБЛАСТИ ПРИМЕНЕНИЯ</article-title><trans-title-group xml:lang="en"><trans-title>HETRBAL PREPARATIONS FROM MILK THISTLE: NEW FIELDS OF APPLICATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брель</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Brel</surname><given-names>Y. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лызиков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyzikov</surname><given-names>A. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Питкевич</surname><given-names>Э. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pitkevich</surname><given-names>E. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2010</year></pub-date><volume>0</volume><issue>1</issue><fpage>129</fpage><lpage>134</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Брель Ю.И., Лызиков А.Н., Питкевич Э.С., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Брель Ю.И., Лызиков А.Н., Питкевич Э.С.</copyright-holder><copyright-holder xml:lang="en">Brel Y.I., Lyzikov A.N., Pitkevich E.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/932">https://journal.gsmu.by/jour/article/view/932</self-uri><abstract><p>В настоящее время наблюдается рост числа экспериментальных и клинических исследований, связанный с открытием новых свойств препаратов расторопши, применяемых в медицине в качестве гепатопротекторов. Активно изучаются механизмы противоопухолевого действия основного действующего компонента данного лекарственного растения - силимарина. Предлагаемый обзор освещает возможности применения препаратов расторопши при различных патологических состояниях.</p></abstract><trans-abstract xml:lang="en"><p>Nowadays the increase of experimental and clinical investigations associated with the discovery of new properties of herbal preparations from Milk Thistle is observed. The anticancer activity of the main active component of this herbal drug - silymarin - is studied. This review demonstrates possibilities of Milk Thistle clinical use in different pathological states.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>расторопша пятнистая</kwd><kwd>силимарин</kwd><kwd>клиническое применение</kwd><kwd>Milk Thistle</kwd><kwd>silymarin</kwd><kwd>clinical use</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pharmacology of Silymarin / F. Fraschini [et al.] // Clin. Drug Invest. - 2002. - Vol. 22, № 1. - P. 51-65.</mixed-citation><mixed-citation xml:lang="en">Pharmacology of Silymarin / F. Fraschini [et al.] // Clin. Drug Invest. - 2002. - Vol. 22, № 1. - P. 51-65.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ramasamy, K. Multitargeted therapy of cancer by silymarin / K. Ramasamy K. R. 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