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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2009-6-3-5</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-846</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>АНАЛИЗ КЛИНИКО-МОРФОЛОГИЧЕСКИХ ПАРАМЕТРОВ ПРИ РАЗВИТИИ РАННИХ РЕЦИДИВОВ У ПАЦИЕНТОВ С ПЕРВИЧНО- ОПЕРАБЕЛЬНЫМ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ</article-title><trans-title-group xml:lang="en"><trans-title>ANALYSIS OF CLINICAL-MORPHOLOGICAL INDICATORS AT DEVELOPMENT OF EARLY RELAPSES IN PATIENTS WITH INITIALLY OPERABLE BREAST CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Надыров</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nadyrov</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Республиканский научно-практический центр радиационной медицины и экологии человека</institution></aff><aff xml:lang="en"><institution>Republican Research Center for Radiation Medicine and Human Ecology</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2009</year></pub-date><volume>0</volume><issue>3</issue><fpage>26</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Надыров Э.А., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Надыров Э.А.</copyright-holder><copyright-holder xml:lang="en">Nadyrov E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/846">https://journal.gsmu.by/jour/article/view/846</self-uri><abstract><p>Изучены основные клинико-диагностические показатели при различных исходах рака молочной железы. Показано, что раннее прогрессирование заболевания (до 3-х лет) определяется размерами опухоли, метастатическим поражением лимфатических узлов, высокой гистологической степенью злокачественности, возрастом на момент заболевания, а также комбинацией рецепторов половых гормонов.</p></abstract><trans-abstract xml:lang="en"><p>We studied the major clinical-diagnostic indicators with different clinical outcomes of breast cancer. We show that early disease progression (up to 3 years) is defined by tumor size, lymph nodes metastases, high histological degree of malignancy, age at the moment of disease, as well as the combination of sex hormone receptors.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>прогрессия заболевания</kwd><kwd>клинические и диагностические маркеры</kwd><kwd>breast cancer</kwd><kwd>disease progression</kwd><kwd>clinical and diagnostic markers</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials / M. 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