zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2009-6-2-4zdor-814Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEСТРУКТУРА, ЛАТЕНТНЫЙ ПЕРИОД И КУМУЛЯТИВНЫЙ РИСК РАЗВИТИЯ ВТОРЫХ ОПУХОЛЕЙ У ПАЦИЕНТОВ, ПОЛУЧАВШИХ ЛЕЧЕНИЕ ПО ПОВОДУ ЗЛОКАЧЕСТВЕННОГО НОВООБРАЗОВАНИЯ В ДЕТСКОМ ВОЗРАСТЕSTRUCTURE, LATENCY TIME AND CUMULATIVE RISK OF DEVELOPING OF THE SECOND TUMORS AT THE PATIENTS TAKING A COURSE OF TREATMENT FOR A MALIGNANT NEOPLASM IN CHILDHOOD PERIODРомашевскаяИ. П.RomashevskayaI. P.noemail@neicon.ruРеспубликанский научно-практический центр детской онкологии и гематологииRepublican Research Centre of Child Oncology and Haematology200928062009022126Copyright © Ромашевская И.П., 20092009Ромашевская И.П.Romashevskaya I.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/814

Представлены случаи заболеваемости вторыми опухолями (1989-2007 гг.) у больных, проходивших лечение по поводу злокачественного новообразования в детском возрасте, а также дискутируется структура предшествующей патологии, латентный период и кумулятивный риск развития вторых опухолей с учетом имеющихся на сегодняшний день литературных данных.

The sickness rate - 59 cases of morbidity for the second tumors (1989-2007) among the sick taking a course of treatment for a malignant neoplasm in childhood period is presented, also structure of preceding pathology, latency time and cumulative risk of developing of the second tumors taking into consideration modern literary data is discussed.

вторая опухользлокачественное новообразование в детском возрастеthe second tumora malignant neoplasm in childhood periodReferencesThe incidence of secondary leukemias / G. Leone [et al.] // Haematologica. - 1999. - Vol. 84. - P. 937-945.The incidence of secondary leukemias / G. Leone [et al.] // Haematologica. - 1999. - Vol. 84. - P. 937-945.Acute myeloid leukemia and myelodysplastic syndrome in children treated for cancer: comparison with primary presentation / D. Barnard [et al.] // Blood. - 2002. - Vol. 100. - P. 427-434.Acute myeloid leukemia and myelodysplastic syndrome in children treated for cancer: comparison with primary presentation / D. Barnard [et al.] // Blood. - 2002. - Vol. 100. - P. 427-434.Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia / C. H. Pui [et al.] // J. Clin. Oncol. - 2005. - Vol. 23. - P. 7936-7941.Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia / C. H. Pui [et al.] // J. Clin. Oncol. - 2005. - Vol. 23. - P. 7936-7941.Risk of subsequent malignant neoplasms among 1,641 Hodgkin's disease patients diagnosed in childhood and adolescence: a population-based cohort study in the five Nordic countries / R. Sankila [et al.] // J. Clin. Oncol. - 1996. - Vol. 14. - P. 1442-1445.Risk of subsequent malignant neoplasms among 1,641 Hodgkin's disease patients diagnosed in childhood and adolescence: a population-based cohort study in the five Nordic countries / R. Sankila [et al.] // J. Clin. Oncol. - 1996. - Vol. 14. - P. 1442-1445.Low risk of secondary leukemias after chemotherapy without mechlorethamine in childhood Hodgkin's disease / G. Shellong [et al.] // J Clin Oncol. - 1997. - Vol. 15. - P. 22472-22453.Low risk of secondary leukemias after chemotherapy without mechlorethamine in childhood Hodgkin's disease / G. Shellong [et al.] // J Clin Oncol. - 1997. - Vol. 15. - P. 22472-22453.Risk of leukemia following treatment for non Hodgkin's lymphoma / L. B. Travis [et al.] // J. Natl Cancer Inst. - 1994. - Vol. 86. - P. 1450-1457.Risk of leukemia following treatment for non Hodgkin's lymphoma / L. B. Travis [et al.] // J. Natl Cancer Inst. - 1994. - Vol. 86. - P. 1450-1457.Treatment-related myelodysplasia and acute leukemia in non-Hodgkin's lymphoma patients / J. O. Armitage [et al.] // J. Clin Oncol. - 2003. - Vol. 21. - P. 897-906.Treatment-related myelodysplasia and acute leukemia in non-Hodgkin's lymphoma patients / J. O. Armitage [et al.] // J. Clin Oncol. - 2003. - Vol. 21. - P. 897-906.

The authors declare that there are no conflicts of interest present.