zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2008-5-2-31zdor-710Research ArticleОБЩЕСТВЕННОЕ ЗДОРОВЬЕ И ЗДРАВООХРАНЕНИЕ, ГИГИЕНАPUBLIC HEALTH AND HEALTH CARE, HYGIENEАЛКОГОЛЬ И СМЕРТНОСТЬ ОТ ПАНКРЕАТИТА: ПОПУЛЯЦИОННЫЙ УРОВЕНЬ ВЗАИМОСВЯЗИALCOHOL AND DEATH-RATE FROM PANCREATITIS: POPULATION LEVEL OF INTERCONNECTIONРазводовскийЮ. Е.RazvodovskyU. E.noemail@neicon.ruГродненский государственный медицинский университетGrodno State Medical University20082806200802138142Copyright © Разводовский Ю.Е., 20082008Разводовский Ю.Е.Razvodovsky U.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/710

В настоящей работе проведен сравнительный анализ динамики уровня смертности от панкреатита, а также смертности в результате острых алкогольных отравлений в России в период с 1956 по 2005 гг. Анализ временных серий свидетельствует о существовании статистически значимой взаимосвязи между динамикой уровня смертности в результате острых алкогольных отравлений и уровня смертности от панкреатита как среди мужчин (r = 0,74; SE = 0,14), так и среди женщин (r = 0,50; SE = 0,14) на нулевом лаге. Результаты настоящего исследования свидетельствуют в пользу гипотезы, согласно которой интоксикационно-ориентированный паттерн потребления алкоголя является фактором риска смертности от панкреатита.

In present work we focused on comparative analysis trends of mortality due to pancreatitis and fatal alcohol poisoning in Russia in 1965-2005. ARIMA time series analysis suggests a positive association between pancreatitis mortality rate and fatal alcohol poisoning rate for male (r = 0,74; SE = 0,14), and female (r = 0,50; SE = 0,14) at zero lag. According to outcomes of present study the intoxication-oriented pattern of alcohol consumption is a risk factor for mortality due to pancreatitis for male, as well as for female.

алкогольные отравлениясмертность от панкреатитаРоссия1965-2005 ггalcohol poisoningmortality due to pancreatitisRussia1965-2005ReferencesНемцов, А. В. Алкогольная смертность в России, 1980-1990 гг. / А. В. Немцов. - М., 2001.Немцов, А. В. Алкогольная смертность в России, 1980-1990 гг. / А. В. Немцов. - М., 2001.Разводовский, Ю. Е. Алкоголь и смертность в Беларуси / Ю. Е. Разводовский. - Гродно, 2003.Разводовский, Ю. Е. Алкоголь и смертность в Беларуси / Ю. Е. Разводовский. - Гродно, 2003.Acute ethanol administration induces oxidative changes in rat pancreatic tissue / E. Altomare [et al.] // Gut. - 1996. - Vol. 38. - P. 742-746.Acute ethanol administration induces oxidative changes in rat pancreatic tissue / E. Altomare [et al.] // Gut. - 1996. - Vol. 38. - P. 742-746.Ethanol-induced alterations in messenger RNA levels correlate with glandular content of pancreatic enzymes / M. V. Apte [et al.] // Journal of Laboratory and Clinical Medicine. - 1995. - Vol. 125. - P. 634-640.Ethanol-induced alterations in messenger RNA levels correlate with glandular content of pancreatic enzymes / M. V. Apte [et al.] // Journal of Laboratory and Clinical Medicine. - 1995. - Vol. 125. - P. 634-640.Box, G. E. P. Time Series Analysis: forecasting and control / G. E. P. Box, G. M. Jenkins. - London: Holden-Day Inc., 1976.Box, G. E. P. Time Series Analysis: forecasting and control / G. E. P. Box, G. M. Jenkins. - London: Holden-Day Inc., 1976.Chronic alcohol сconsumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats / X. Deng [et al.] // American Journal of Pathology. - 2005. - Vol. 166. - P. 93-106.Chronic alcohol сconsumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats / X. Deng [et al.] // American Journal of Pathology. - 2005. - Vol. 166. - P. 93-106.Dufour, M. C. The epidemiology of alcohol-induced pancreatitis / M. C. Dufour, M. D. Adamson // Pancreas. - 2003. - Vol. 27, N. 4. - P. 286-290.Dufour, M. C. The epidemiology of alcohol-induced pancreatitis / M. C. Dufour, M. D. Adamson // Pancreas. - 2003. - Vol. 27, N. 4. - P. 286-290.Durkec, J. P. Multicenter survey of the etiology of pancreatic disease: the relationship between the relative risk of developing chronic pancreatitis and alcohol, protein and lipid consumption / J. P. Durkec, H. Sarles Digestion. - 1978. - Vol. 18. - P. 337-350.Durkec, J. P. Multicenter survey of the etiology of pancreatic disease: the relationship between the relative risk of developing chronic pancreatitis and alcohol, protein and lipid consumption / J. P. Durkec, H. Sarles Digestion. - 1978. - Vol. 18. - P. 337-350.Pathophysiology of alcohol-induced pancreatitis / M. M. Lerch [et al.] // Pancreas. - 2003. - Vol. 27, N. 4. - P. 291-296.Pathophysiology of alcohol-induced pancreatitis / M. M. Lerch [et al.] // Pancreas. - 2003. - Vol. 27, N. 4. - P. 291-296.Norstrom, T. Alcohol and mortality: methodological and analytical issue in aggregate analysis / T. Norstrom, O. J. Skog // Addiction. - 2001. - Vol. 96. - P. 5-17.Norstrom, T. Alcohol and mortality: methodological and analytical issue in aggregate analysis / T. Norstrom, O. J. Skog // Addiction. - 2001. - Vol. 96. - P. 5-17.Norton, I. P4502E1 is present in rat pancreas and is induced by chronic ethanol administration / I. Norton, P. Haber // Gastroenterology. - 1996. - Vol. 110. - P. 1280.Norton, I. P4502E1 is present in rat pancreas and is induced by chronic ethanol administration / I. Norton, P. Haber // Gastroenterology. - 1996. - Vol. 110. - P. 1280.Potentiation of ethanol-induced pancreatic injury by dietary fat / H. Tsukamoto [et al.] // Am J. Pathol. - 1988. - Vol. 131. - P. 246-257.Potentiation of ethanol-induced pancreatic injury by dietary fat / H. Tsukamoto [et al.] // Am J. Pathol. - 1988. - Vol. 131. - P. 246-257.Whitcomb, D. C. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene / D. C. Whitcomb, M. C. Gorry, R. A. Preston // Nature Genetics. - 1996. - Vol. 14. - P. 141-145.Whitcomb, D. C. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene / D. C. Whitcomb, M. C. Gorry, R. A. Preston // Nature Genetics. - 1996. - Vol. 14. - P. 141-145.

The authors declare that there are no conflicts of interest present.