zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2007-4-4-30zdor-613Research ArticleМЕДИЦИНСКИЕ АСПЕКТЫ ЧЕРНОБЫЛЬСКОЙ КАТАСТРОФЫИОНИЗИРУЮЩАЯ РАДИАЦИЯ И ЛЕЙКОЗЫ В КОНТЕКСТЕ ЗАБОЛЕВАЕМОСТИ ДЕТЕЙ БЕЛАРУСИ ПОСЛЕ АВАРИИ НА ЧАЭСIonizing radiation and leukemia in relation to the incidence in children of Belarus after the Chernobyl accidentСавваН. Н.SavvaN. N.noemail@neicon.ruХошиМ. .HoshiM. .noemail@neicon.ruАлейниковаО. В.AleinikovaO. V.noemail@neicon.ruРеспубликанский научно-практический центр детской онкологии и гематологииBelarusian Research Center for Pediatric Oncology and HematologyХиросимский университетHiroshima UniversityНаучно-исследовательский институт радиационной биологии и медициныResearch Institute for Radiation Biology and Medicine20072812200704137141Copyright © Савва Н.Н., Хоши М..., Алейникова О.В., 20072007Савва Н.Н., Хоши М..., Алейникова О.В.Savva N.N., Hoshi M..., Aleinikova O.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/613

В статье приводятся научные сведения, касающиеся риска возникновения лейкозов у детей в результате воздействия низких доз ионизирующей радиации, описаны результаты основных завершенных эпидемиологических исследований лейкозов у детей Беларуси в постчернобыльский период, обсуждается необходимость дальнейшего изучения данного вопроса с учетом последних рекомендаций международного Чернобыльского форума и Всемирной организации здравоохранения.

The article contains the scientific facts regarding the radiogenic leukemia risks in children after the exposure of low doses ionizing radiation, as well as the results of the main completed epidemiological childhood leukemia studies in Belarus after the Chernobyl accident, and a discussion of the necessity of further researches taking into account the recommendations of the Chernobyl Forum and World Health Organization.

ионизирующая радиациялейкозыдетиавария на ЧАЭСionizing radiationleukemiachildrenChernobylReferencesRecommendations of the international commission on radiological protection, publication 60 / International Commission on Radiological Protection (ICRP) // International Commission on Radiological Protection. - Oxford, Program Press, 1991.Recommendations of the international commission on radiological protection, publication 60 / International Commission on Radiological Protection (ICRP) // International Commission on Radiological Protection. - Oxford, Program Press, 1991.Doll, R. Risk of childhood cancer from fetal irradiation / R. Doll, R. Wakeford // Br. J. Radiol. - 1997. - Vol. 70. - P. 130-139.Doll, R. Risk of childhood cancer from fetal irradiation / R. Doll, R. Wakeford // Br. J. Radiol. - 1997. - Vol. 70. - P. 130-139.Sources and effects of ionizing radiation / United Nations Scientific Committee on the effects of atomic radiation (UNSCEAR) // Report to the General Assembly, E.94.IX.11. - New York: United Nations. - 1994.Sources and effects of ionizing radiation / United Nations Scientific Committee on the effects of atomic radiation (UNSCEAR) // Report to the General Assembly, E.94.IX.11. - New York: United Nations. - 1994.Genetic and somatic effects of ionizing radiation / United Nations Scientific Committee on the effects of Atomic Radiation (UNSCEAR) // Report to the General Assembly, 86.IX.9. - New York, Unites Nations, 1986.Genetic and somatic effects of ionizing radiation / United Nations Scientific Committee on the effects of Atomic Radiation (UNSCEAR) // Report to the General Assembly, 86.IX.9. - New York, Unites Nations, 1986.Risk of cancer among children exposed in utero to A-bomb radiations, 1950-1984 / Y. Yoshimoto // Lancet. - 1988. - № 2. - P. 665-669.Risk of cancer among children exposed in utero to A-bomb radiations, 1950-1984 / Y. Yoshimoto // Lancet. - 1988. - № 2. - P. 665-669.Late Health Effects from Radiation: Knowledge gained from the 60 years’ experience in Japan / WHO, HQ // Report. - Geneva: World Health Organisation, 2005.Late Health Effects from Radiation: Knowledge gained from the 60 years’ experience in Japan / WHO, HQ // Report. - Geneva: World Health Organisation, 2005.Implication of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia / H. Harada [et al.] // Blood. - 2003. - № 2. - P. 673-680.Implication of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia / H. Harada [et al.] // Blood. - 2003. - № 2. - P. 673-680.Evaluation of the linear nonthreshold dose-response model for ionizing radiation / National Council on Radiation Protection and Measurements // Report № 136. - Bethesda: NCR. - 2001.Evaluation of the linear nonthreshold dose-response model for ionizing radiation / National Council on Radiation Protection and Measurements // Report № 136. - Bethesda: NCR. - 2001.Childhood leukemia in Belarus before and after the Chernobyl accident: continued follow-up / V. Gapanovich [et al.] // Radiat. Environ. Biophys. - 2001. - № 4. - P. 259-267.Childhood leukemia in Belarus before and after the Chernobyl accident: continued follow-up / V. Gapanovich [et al.] // Radiat. Environ. Biophys. - 2001. - № 4. - P. 259-267.Childhood leukemia in Belarus before and after the Chernobyl accident / E. Ivanov [et al.] // Radiat. Environ. Biophys. - 1996. - Vol. 35. - P. 75-80.Childhood leukemia in Belarus before and after the Chernobyl accident / E. Ivanov [et al.] // Radiat. Environ. Biophys. - 1996. - Vol. 35. - P. 75-80.Infant leukaemia after in utero exposure to radiation from Chernobyl / E. Petridou [et al.] // Nature. - 1996. - № 1. - P. 352-353.Infant leukaemia after in utero exposure to radiation from Chernobyl / E. Petridou [et al.] // Nature. - 1996. - № 1. - P. 352-353.Trends in infant leukaemia in West Germany in relation to in utero exposure due to Chernobyl accident / M. Steiner [et al.] // Radiat. Environ. Biophys. - 1998. - № 2. - P. 87-93.Trends in infant leukaemia in West Germany in relation to in utero exposure due to Chernobyl accident / M. Steiner [et al.] // Radiat. Environ. Biophys. - 1998. - № 2. - P. 87-93.Infant leukemia in Belarus after the Chernobyl accident / E. Iva-nov [et al.] // Radiat. Environ. Biophys. - 1998. - № 1. - P. 53-55.Infant leukemia in Belarus after the Chernobyl accident / E. Iva-nov [et al.] // Radiat. Environ. Biophys. - 1998. - № 1. - P. 53-55.Epidemiology of childhood cancer in Belarus: review of data 1978-1994, and discussion of the new Belarusian Childhood Cancer Registry / van Hoff. J. [et al.] // Stem Cells. - 1997. - Vol. 15, № 2. - P. 231-241.Epidemiology of childhood cancer in Belarus: review of data 1978-1994, and discussion of the new Belarusian Childhood Cancer Registry / van Hoff. J. [et al.] // Stem Cells. - 1997. - Vol. 15, № 2. - P. 231-241.Заболеваемость острыми лейкозами детей Беларуси: дескриптивный анализ данных периода 1990-2004 гг. / Н. Н. Савва [и др.] // Вопросы гематологии/онкологии и иммунопатологии в педиатрии. - 2007. - № 1 - С. 5-10.Заболеваемость острыми лейкозами детей Беларуси: дескриптивный анализ данных периода 1990-2004 гг. / Н. Н. Савва [и др.] // Вопросы гематологии/онкологии и иммунопатологии в педиатрии. - 2007. - № 1 - С. 5-10.Childhood leukemia in Belarus, Russia, and Ukraine following the Chernobyl power station accident: results from an international collaborative population-based case-control study / S. Davis [et al.] // Int. J. Epidemiol. - 2006. - Vol. 35. - P. 386-396.Childhood leukemia in Belarus, Russia, and Ukraine following the Chernobyl power station accident: results from an international collaborative population-based case-control study / S. Davis [et al.] // Int. J. Epidemiol. - 2006. - Vol. 35. - P. 386-396.Оценка радиационных рисков заболеваемости острыми лейкозами детей Беларуси / Е. П. Иванов [и др.] // VI Съезд гематологов и трансфузиологов Республики Беларусь «Актуальные проблемы гематологии и трансфузиологии». 24-25 мая, 2007, Минск. - С. 160Оценка радиационных рисков заболеваемости острыми лейкозами детей Беларуси / Е. П. Иванов [и др.] // VI Съезд гематологов и трансфузиологов Республики Беларусь «Актуальные проблемы гематологии и трансфузиологии». 24-25 мая, 2007, Минск. - С. 160Leukaemia incidence and survival in children and adolescents in Europe during 1978-1997. Report from the Automated Childhood Cancer Information System project / J. Coebergh [et al.] // Eur. J. Cancer. - 2006. - № 13. - P. 2019-2036.Leukaemia incidence and survival in children and adolescents in Europe during 1978-1997. Report from the Automated Childhood Cancer Information System project / J. Coebergh [et al.] // Eur. J. Cancer. - 2006. - № 13. - P. 2019-2036.Childhood leukaemia in Europe after Chernobyl: 5 year follow-up / D. Parkin [et al.] // Br. J. Cancer. - 1996. - № 8. - P. 1006-1012.Childhood leukaemia in Europe after Chernobyl: 5 year follow-up / D. Parkin [et al.] // Br. J. Cancer. - 1996. - № 8. - P. 1006-1012.Chernobyl’s Legacy: Health, Environmental and Socio-Economic Impacts and Recommendations to the Governments of Belarus, the Russian Federation and Ukraine / WHO, IAEA, UNDP // The Chernobyl Forum: 2003-2005, Second revised version. - Austria: World Health Organisation. - 2006.Chernobyl’s Legacy: Health, Environmental and Socio-Economic Impacts and Recommendations to the Governments of Belarus, the Russian Federation and Ukraine / WHO, IAEA, UNDP // The Chernobyl Forum: 2003-2005, Second revised version. - Austria: World Health Organisation. - 2006.Health effects of the Chernobyl accident and special health care programs / World Health Organisation (WHO) // Report of United Nations Chernobyl Forum, Expert Group Health; ed. by Benett B, Repacholi M, Carr Z. - Geneva, World Health Organisation. - 2006.Health effects of the Chernobyl accident and special health care programs / World Health Organisation (WHO) // Report of United Nations Chernobyl Forum, Expert Group Health; ed. by Benett B, Repacholi M, Carr Z. - Geneva, World Health Organisation. - 2006.Health Effects of the Chernobyl Accident: an overview / World Health Organisation (WHO) // Fact sheet № 303. - Geneva, World Health Organisation. - 2006.Health Effects of the Chernobyl Accident: an overview / World Health Organisation (WHO) // Fact sheet № 303. - Geneva, World Health Organisation. - 2006.Sources and effects of ionizing radiation / United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) // Report to the General Assembly, Annex J. - New York: United Nations. - 2000.Sources and effects of ionizing radiation / United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) // Report to the General Assembly, Annex J. - New York: United Nations. - 2000.

The authors declare that there are no conflicts of interest present.