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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2026-23-1-01</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2833</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Особенности иммуноэндокринных взаимодействий в системе «мать – плацента – плод» при патологии щитовидной железы</article-title><trans-title-group xml:lang="en"><trans-title>Features of immune and endocrine interactions in the mother-placenta-fetus system in thyroid pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1557-7470</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaitseva</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зайцева Ольга Александровна, ассистент кафедры педиатрии с курсом ФПКиП</p><p>г. Гомель </p></bio><bio xml:lang="en"><p>Olga A. Zaitseva, Assistant Lecturer at the Department of Pediatrics with the course of Advanced Training and Retraining</p><p>Gomel </p></bio><email xlink:type="simple">zajkina@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3061-5324</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зыблева</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zybleva</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зыблева Светлана Валерьевна, д.м.н., доцент, заместитель директора (по медицинской части)</p><p>г. Гомель </p></bio><bio xml:lang="en"><p>Svetlana V. Zybleva, Doctor of Medical Sciences, Associate Professor, Deputy Director (Medical)  </p><p>Gomel </p></bio><email xlink:type="simple">zyb-svetlana@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-7881-3460</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тихонова</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsikhanava</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тихонова Екатерина Сергеевна, врач аллерголог-иммунолог отделения аллергологии и иммунопатологии </p><p>г. Гомель </p></bio><bio xml:lang="en"><p>Katsiaryna S. Tsikhanava, Allergologist and Immunopatholist at the Department of Allergiology and Immunopathology </p><p>Gomel </p></bio><email xlink:type="simple">stusha@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6965-6794</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарко</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharko</surname><given-names>A. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захарко Анна Юрьевна, к.м.н., врач акушер-гинеколог</p><p>г. Гомель </p></bio><bio xml:lang="en"><p>Anna U. Zakharko, Candidate of Medical Sciences, Obstetrics and Gynecology Doctor </p><p>Gomel </p></bio><email xlink:type="simple">annazakharko@tut.by</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4783-6166</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рожко</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rozhko</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рожко Валентин Александрович, к.м.н., старший научный сотрудник лаборатории эпидемиологии </p><p>г. Гомель </p></bio><bio xml:lang="en"><p>Valentin A. Rozhko, Candidate of Medical Sciences, Senior Researcher at the Epidemiology Laboratory </p><p>Gomel </p></bio><email xlink:type="simple">yrahara@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Республиканский научно-практический центр радиационной медицины и экологии человека</institution></aff><aff xml:lang="en"><institution>Republican Research Center for Radiation Medicine and Human Ecology</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>16</day><month>04</month><year>2026</year></pub-date><volume>23</volume><issue>1</issue><fpage>7</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зайцева О.А., Зыблева С.В., Тихонова Е.С., Захарко А.Ю., Рожко В.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Зайцева О.А., Зыблева С.В., Тихонова Е.С., Захарко А.Ю., Рожко В.А.</copyright-holder><copyright-holder xml:lang="en">Zaitseva O.A., Zybleva S.V., Tsikhanava K.S., Zakharko A.U., Rozhko V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2833">https://journal.gsmu.by/jour/article/view/2833</self-uri><abstract><p>В статье представлен обзор отечественной и зарубежной литературы, где публикуются данные исследований по вопросам иммуноэндокринных взаимодействий с особым акцентом на патологические отклонения уровней содержания гормонов щитовидной железы (ЩЖ) и влияния нарушений тиреоидного статуса на развитие осложнений беременности и родов у женщин, здоровье новорожденного и детей в постнатальном периоде. Рассматриваются эндокринные нарушения функции ЩЖ — гипотиреоз, тиреотоксикоз, аутоиммунный тиреоидит, а также йододефицит как одна из причин этих нарушений. В статье представлены междисциплинарные исследования в области иммунологии и эндокринологии. Проведен анализ данных по теме статьи в отечественной и зарубежной литературе.</p><p>Использовались базы Pubmed, Elibrary, Scholar.google, Cyberleninka.ru.</p></abstract><trans-abstract xml:lang="en"><p>The article provides an overview of domestic and foreign literature, including studies data on immune and endocrine interactions with a special focus on pathological deviations in thyroid hormones levels and the impact of thyroid status disorders on the development of complications during pregnancy and childbirth in women, the health of the newborn and children in the postnatal period. Endocrine disorders of the thyroid gland are considered – hypothyroidism, thyrotoxicosis, autoimmune thyroiditis, as well as iodine deficiency as one of the causes of these disorders. The article presents interdisciplinary research in the field of immunology and endocrinology.</p><p>The analysis of domestic and foreign literature on the topic of publication is carried out. The databases Pubmed, Elibrary, Scholar.google, Cyberleninka.ru were used.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>иммуноэндокринные взаимодействия</kwd><kwd>гипотиреоз</kwd><kwd>тиреотоксикоз</kwd><kwd>аутоиммунный тиреоидит</kwd><kwd>дефицит йода</kwd><kwd>беременность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>immune and endocrine interactions</kwd><kwd>hypothyroidism</kwd><kwd>thyrotoxicosis</kwd><kwd>autoimmune thyroiditis</kwd><kwd>iodine deficiency</kwd><kwd>pregnancy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Yavropoulou MP, Sfikakis PP, Chrousos GP. Immune System Effects on the Endocrine System. In: Feingold KR, Ahmed SF, Anawalt B, et al., eds. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; November 8, 2023. [date of access 2025 March 10]. 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