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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2024-21-4-15</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2747</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Первичная лимфома головного мозга у ВИЧ-инфицированного пациента</article-title><trans-title-group xml:lang="en"><trans-title>Primary lymphoma of the brain in an HIV-infected patient</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5936-7622</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терешковец</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tereshkovets</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Терешковец Александр Сергеевич, старший преподаватель кафедры патологической анатомии</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Aleksandr S. Tereshkovets, Senior Lecturer at the Department of Pathological Anatomy</p><p>Gomel</p></bio><email xlink:type="simple">a.tereshkovets@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0532-148X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шибанова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shibanova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шибанова Людмила Александровна, к.м.н., доцент, заведующий кафедрой патологической анатомии</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Ludmila A. Shibanova, Candidate of Medical Sciences, Associate Professor, Head of the Department of Pathological Anatomy</p><p>Gomel</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4714-4592</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лось</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Los’</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лось Дмитрий Михайлович, начальник отдела науки, медицинской информации и клинических испытаний</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Dmitry M. Los’, Head of the Department of Science, Medical Information and Clinical Trials </p><p>Gomel</p></bio><email xlink:type="simple">dimalos@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0172-0320</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ачинович</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Achinovich</surname><given-names>S. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ачинович Сергей Леонидович, к.м.н., доцент, заведующий патологоанатомическим отделением</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Sergey L. Achinovich, Candidate of Medical Sciences, Associate Professor, Head of Pathological Anatomy Department</p><p>Gomel</p></bio><email xlink:type="simple">ser.achinowitch2017@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-5062-0818</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михед</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhed</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михед Татьяна Михайловна, заведующий инфекционным отделением № 2</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Tatyana M. Mikhed, Head of the Department of Infectious Disease No.2</p><p>Gomel</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-6859-1693</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зятиков</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zyatikov</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зятиков Роман Викторович, врач-патологоанатом</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Roman V. Zyatikov, Pathologist</p><p>Gomel</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Гомельский областной клинический онкологический диспансер</institution></aff><aff xml:lang="en"><institution>Gomel Regional Clinical Oncology Dispensary</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Гомельская областная клиническая инфекционная больница</institution></aff><aff xml:lang="en"><institution>Gomel Regional Clinical Infectious Diseases Hospital</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Гомельское областное клиническое патологоанатомическое бюро</institution></aff><aff xml:lang="en"><institution>Gomel Regional Clinical regional Pathoanatomical Bureau</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>16</day><month>01</month><year>2025</year></pub-date><volume>21</volume><issue>4</issue><fpage>142</fpage><lpage>148</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Терешковец А.С., Шибанова Л.А., Лось Д.М., Ачинович С.Л., Михед Т.М., Зятиков Р.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Терешковец А.С., Шибанова Л.А., Лось Д.М., Ачинович С.Л., Михед Т.М., Зятиков Р.В.</copyright-holder><copyright-holder xml:lang="en">Tereshkovets A.S., Shibanova L.A., Los’ D.M., Achinovich S.L., Mikhed T.M., Zyatikov R.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2747">https://journal.gsmu.by/jour/article/view/2747</self-uri><abstract><p>В статье представлен клинический случай первичной лимфомы головного мозга, обнаруженной у ВИЧ-инфицированного пациента. Описаны клинические проявления представленной патологии, а также используемые методы для ее диагностики. Данный случай представляет собой научный интерес для врачей различных специальностей, так как поражение головного мозга у иммунокомпрометированных пациентов может проявляться широким спектром заболеваний различной этиологии с множеством клинических и патоморфологических проявлений, при этом большинство патологических состояний не имеет патогномоничных симптомов и может обладать вариабельными клиническими симптомами.</p></abstract><trans-abstract xml:lang="en"><p>This article presents a clinical case of primary cerebral lymphoma diagnosed in an HIV-infected patient. Clinical manifestations of the presented pathology, and the methods for its diagnostic were described. This case is of scientific interest to doctors of various specialities, as brain lesions in immunocompromised patients may manifest with a wide range of diseases of different etiologies, with a variety of clinical and pathomorphological features, moreover the most of pathological conditions do not have pathognomonic symptoms and may have variable clinical symptoms.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лимфома</kwd><kwd>ВИЧ-инфекция</kwd><kwd>первичная лимфома мозга</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lymphoma</kwd><kwd>HIV-infection</kwd><kwd>primary brain lymphoma</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование проведено без спонсорской поддержки.</funding-statement><funding-statement xml:lang="en">The study was conducted without sponsorship.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Океанов А.Е., Моисеев П.И., Левин Л.Ф.; под ред. 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