<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2024-21-1-17</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2706</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Агрессивное течение гиперплазии язычной миндалины</article-title><trans-title-group xml:lang="en"><trans-title>Clinical case of aggressive course of hyperplasia of the lingual tonsil</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6849-2951</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шляга</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Shlyaga</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ирина Дмитриевна Шляга, к. м. н., доцент, заведующий кафедрой</p><p>кафедра оториноларингологии с курсом офтальмологии</p><p>Гомель</p></bio><bio xml:lang="en"><p>Irina D. Shlyaga, Candidate of Medical Sciences, Associate Professor, Associate Professor at the Department</p><p>Department of Otorhinolaryngology with the course of Ophthalmology</p><p>Gomel</p></bio><email xlink:type="simple">Irina.Shljaga@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3267-5542</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Межейникова</surname><given-names>М. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Miazheinikava</surname><given-names>M. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марина Олеговна Межейникова, ассистент</p><p>кафедра оториноларингологии с курсом офтальмологии</p><p>Гомель</p></bio><bio xml:lang="en"><p>Maryna O. Miazheinikava, Assistant Lecturer</p><p>Department of Otorhinolaryngology with the course of Ophthalmology</p><p>Gomel</p></bio><email xlink:type="simple">miazheinikavamaryna@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4892-2499</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Челебиева</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Cheliabiyeva</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наталья Петровна Челебиева, ассистент</p><p>кафедра оториноларингологии с курсом офтальмологии</p><p>Гомель</p></bio><bio xml:lang="en"><p>Natallia P. Cheliabiyeva, Assistant Lecturer</p><p>Department of Otorhinolaryngology with the course of Ophthalmology</p><p>Gomel</p></bio><email xlink:type="simple">chel.natalia@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8905-4296</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Главацкая</surname><given-names>И. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Hlavatskaya</surname><given-names>I. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ирина Петровна Главацкая, ассистент</p><p>кафедра патологической анатомии</p><p>Гомель</p></bio><bio xml:lang="en"><p>Iryna P. Hlavatskaya, Assistant Lecturer</p><p>Department of Pathological Anatomy</p><p>Gomel</p></bio><email xlink:type="simple">ira.ilyashenko.89@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3405-7668</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тищенко</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tishchenko</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорий Витальевич Тищенко, к. м. н., доцент</p><p>кафедра патологической анатомии</p><p>Гомель</p></bio><bio xml:lang="en"><p>Grigorii V. Tishchenko, Candidate of Medical Sciences, Associate Professor</p><p>Department of Pathological Anatomy</p><p>Gomel</p></bio><email xlink:type="simple">dr.gregory.t@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-7264-6156</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сухарев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Suharev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Александрович Сухарев, врач-оториноларинголог</p><p>Гомель</p></bio><bio xml:lang="en"><p>Alexey A. Suharev, Otorhinolaryngologist</p><p>Gomel</p></bio><email xlink:type="simple">SuharevAlexey.lor@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>31</day><month>03</month><year>2024</year></pub-date><volume>21</volume><issue>1</issue><fpage>138</fpage><lpage>147</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шляга И.Д., Межейникова М.О., Челебиева Н.П., Главацкая И.П., Тищенко Г.В., Сухарев А.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Шляга И.Д., Межейникова М.О., Челебиева Н.П., Главацкая И.П., Тищенко Г.В., Сухарев А.А.</copyright-holder><copyright-holder xml:lang="en">Shlyaga I.D., Miazheinikava M.O., Cheliabiyeva N.P., Hlavatskaya I.P., Tishchenko G.V., Suharev A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2706">https://journal.gsmu.by/jour/article/view/2706</self-uri><abstract><p>   В статье описан клинический случай атипичного агрессивного течения микоз-ассоциированной гиперплазии язычной миндалины с пролиферативными изменениями глоточной, нёбных миндалин. Изложены особенности этиологии, патогенеза, трудностей диагностики и продемонстрирован эффективный метод лечения данной патологии. Опираясь на клинический опыт, нужно отметить, что распространенность заболеваний язычной миндалины значительно выше, чем их выявляемость. Это связано с ее анатомо-топографическими и морфологическими особенностями расположения и строения, а также с относительной трудностью осмотра (высокий глоточный рефлекс), необходимостью владения врачом-специалистом техниками гипофарингоскопии и отсутствием четкого алгоритма клинического обследования таких пациентов.</p></abstract><trans-abstract xml:lang="en"><p>   The article describes a clinical case of atypical aggressive progression of mycosis-associated hyperplasia of the lingual tonsil with proliferative changes in the pharyngeal and palatine tonsils. The features of etiology, pathogenesis, diagnostic challenges, and an effective treatment method for this pathology are presented. Based on clinical experience, it is important to note that the prevalence of lingual tonsil diseases is significantly higher than their detectability. This is attributed to its anatomical-topographical and morphological characteristics of location and structure, as well as the relative difficulty of examination (due to a high pharyngeal reflex), the need for the specialist physician to master hypopharyngoscopy techniques, and the lack of a clear algorithm for clinical examination of such patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>патология глоточно-лимфатического кольца Пирогова – Вальдейера</kwd><kwd>хронические заболевания глотки</kwd><kwd>гипертрофия глоточной миндалины</kwd><kwd>гипертрофия язычной миндалины</kwd><kwd>микоз глотки</kwd><kwd>СО2-лазер</kwd><kwd>патологогистологическое исследование</kwd><kwd>гистохимия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pathology of Pirogov-Valdeyer pharyngeal lymphoid ring</kwd><kwd>chronic throat diseases</kwd><kwd>hypertrophy of the pharyngeal tonsil</kwd><kwd>hypertrophy of the lingual tonsil</kwd><kwd>pharyngeal mycosis</kwd><kwd>CO2 laser</kwd><kwd>pathohistological study</kwd><kwd>histochemistry</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование проведено без спонсорской поддержки</funding-statement><funding-statement xml:lang="en">The research was conducted without sponsorship support</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Пальчун В.Т., Магомедов М.М., Лучихин Л.А. Оториноларингология. ГЕОТАР-Медиа, 2008; 656 c.</mixed-citation><mixed-citation xml:lang="en">Palchun VT, Magomedov MM, Luchikhin LA. Otorhinolaryngology. Moscow: GEOTAR-Media, 2008. 656 p. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Шляга И.Д., Межейникова М.О., Челебиева Н.П., Главацкая И.П., Шалыга И.Ф. Анализ хронической патологии глотки по результатам патологогистологических заключений. Проблемы здоровья и экологии. 2023;20(1):65-74. doi: 10.51523/2708-6011.2023-20-1-08</mixed-citation><mixed-citation xml:lang="en">Shlyaga I.D., Miazheinikava M.O., Cheliabiyeva N.P., Hlavatskaya I.P., Shalyga I.F. Analysis of chronic pathology of the pharynx according to the results of pathohistological findings. Health and Ecology Issues. 2023;20(1):65-74. (In Russ.). doi: 10.51523/2708-6011.2023-20-1-08</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Буцель А.Ч., Долина И.В. Гипертрофия лимфоэпителиального кольца глотки. Учеб.-метод. пособие. Минск: БГМУ, 2011. 14 с.</mixed-citation><mixed-citation xml:lang="en">Butzel ACh, Dolina IV. Hypertrophy of the lymphoepithelial ring of the pharynx. Educational method. allowance. Minsk: BSMU, 2011. 14 p. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Гришунина О.Е., Лейзерман М.Г. Распространенность гипертрофии язычной миндалины и тактика лечения. Проблемы женского здоровья. 2013;8(4):77-79. doi: 10.51523/2708-6011.2023-20-1-08</mixed-citation><mixed-citation xml:lang="en">Shlyaga I.D., Miazheinikava M.O., Cheliabiyeva N.P., Hlavatskaya I.P., Shalyga I.F. Analysis of chronic pathology of the pharynx according to the results of pathohistological findings. Health and Ecology Issues. 2023;20(1):65-74. (In Russ.) doi: 10.51523/2708-6011.2023-20-1-08 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Блоцкий А.А, Антипенко В.В. Гипертрофия язычной миндалины. В: Материалы Межрегиональной научно-практической конференции оториноларингологов Сибири и Дальнего Востока с международным участием «Актуальные вопросы оториноларингологии». 2016;14:111-113.</mixed-citation><mixed-citation xml:lang="en">Blotsky AA, Antipenko VV. Hypertrophy of the lingual tonsil. In: Materials of the Interregional Scientific and Practical Conference of Otorhinolaryngologists of Siberia and the Far East with international participation “Topical Issues of Otorhinolaryngology”. 2016;14:111-113. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Апостолиди К.Г., Савчук О.В., Золотухин С.Ю., Добриков Е.А. Роль оториноларинголога в решении проблемы синдрома обструктивного апное сна и значение эндоскопии верхних дыхательных путей в диагностике этой патологии. Вестник Национального медико-хирургического Центра им. НИ Пирогова. 2021;16(1):158-162. doi: 10.25881/BPNMSC.2021.79.39.030</mixed-citation><mixed-citation xml:lang="en">Apostolidi K.G., Savchuk О.V., Zolotukhin S.Y., Dobrikov E.A. The role of the otorhinolaryngologist in the problem of the obstructive sleep apnea syndrome and the importance of endoscopic upper respiratory pathways in the diagnosis of this pathology. Vestnik Natsional’nogo mediko-khirurgicheskogo Tsentra im. NI Pirogova. 2021;16(1):158-162. (In Russ.). doi: 10.25881/BPNMSC.2021.79.39.030</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Накатис Я.С., Лейзерман М.Г., Гришунина О.Е. Радиочастотная редукция и резекция язычной. Российская оториноларингология. 2012;(6), 114-117.</mixed-citation><mixed-citation xml:lang="en">Nakatis JA, Leyzerman MG, Grishunina OE. Reduction and resection of tongue tonsyl. Rossiiskaya otorinolaringologiya. 2012;(6), 114-117. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Рассолов В.Н. Морфология интактной и гипертрофированной язычной миндалины человека : дис. на соискание ученой степени кандидата мед. наук. Самара: «Медицинский университет «Реавиз». 2020;177. [дата обращения 06. 10. 23]. Режим доступа: https://bashgmu.ru/upload/ученый%20совет/Дис._Рассолов%20(2)%20(1)_compressed.pdf</mixed-citation><mixed-citation xml:lang="en">Rassolov V.N. Morphology of intact and hypertrophied human lingual tonsil : dis. for the scientific degree of Candidate of Medical Sciences. Sci. Samara: “Reaviz Medical University”. 2020;177. https://bashgmu.ru/upload/ученый%20совет/Дис._Рассолов%20(2)%20(1)_compressed.pdf (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Болотин М.В., Мудунов А.М., Азизян Р.И., Саприна О.А. Трансоральные лазерные резекции опухолей полости рта и ротоглотки. Опухоли головы и шеи. 2016;6(1):28-32. doi: 10.17650/2222-1468-2016-6-1-28-32</mixed-citation><mixed-citation xml:lang="en">Bolotin MV, Mudunov AM. Azizyan RI., Saprina OA. Transoral laser resections of oral cavity and oropharyngeal tumors. HEAD and NECK tumors. 2016;6(1):28-32. (In Russ.). doi: 10.17650/2222-1468-2016-6-1-28-32</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Васильева Л.Н., Ксенофонтова А.Г., Баюкова С.В. Фарингомикозы: современные клинические аспекты. В: Антибактериальная терапия в оториноларингологии : материалы Межрегиональной научно-практической конференции, Чебоксары, 28 марта 2019 года. Чебоксары: Чувашский государственный университет имени И.Н. Ульянова, 2019. С. 15-21.</mixed-citation><mixed-citation xml:lang="en">Vasilyeva LN, Ksenofontova AG, Baykova SV. Pharyngomycoses: modern clinical aspects. В: In: Antibacterial therapy in otorhinolaryngology : materials of the Interregional Scientific and Practical Conference, Cheboksary, March 28, 2019. Cheboksary: Chuvash State University named after I.N. Ulyanova, 2019. pp. 15-21. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Stoopler ET, Ojeda D, Elmuradi S, Sollecito TP. Lymphoid hyperplasia of the tongue. Journal of Emergency Medicine. 2016;50(3):e155-e156. doi: 10.1016/j.jemermed.2015.09.042</mixed-citation><mixed-citation xml:lang="en">Stoopler ET, Ojeda D, Elmuradi S, Sollecito TP. Lymphoid hyperplasia of the tongue. Journal of Emergency Medicine. 2016;50(3):e155-e156. doi: 10.1016/j.jemermed.2015.09.042</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Chow TL, Kwan WW. Benign lymphoid hyperplasia of tongue base compromising the airway. Surgical Practice. 2022;26(2):131-132. doi: 10.1111/1744-1633.12570</mixed-citation><mixed-citation xml:lang="en">Chow TL, Kwan WW. Benign lymphoid hyperplasia of tongue base compromising the airway. Surgical Practice. 2022;26(2):131-132. doi: 10.1111/1744-1633.12570</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Carnelio S, Rodrigues G. Benign lymphoid hyperplasia of the tongue masquerading as carcinoma : case report and literature review. J Contemp Dent Pract. 2005;6(3):111-119. doi: 10.5005/jcdp-6-3-111</mixed-citation><mixed-citation xml:lang="en">Carnelio S, Rodrigues G. Benign lymphoid hyperplasia of the tongue masquerading as carcinoma : case report and literature review. J Contemp Dent Pract. 2005;6(3):111-119. doi: 10.5005/jcdp-6-3-111</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Proenca‐Modena JL, de Souza Cardoso R, Criado MF, Milanez GP, de Souza WM, Parise PL, Bertol JW, de Jesus BL, Prates MC, Silva ML, Buzatto GP. Human adenovirus replication and persistence in hypertrophic adenoids and palatine tonsils in children. Journal of medical virology. 2019;91(7):1250-1262. doi: 10.1002/jmv.25441</mixed-citation><mixed-citation xml:lang="en">Proenca‐Modena JL, de Souza Cardoso R, Criado MF, Milanez GP, de Souza WM, Parise PL, Bertol JW, de Jesus BL, Prates MC, Silva ML, Buzatto GP. Human adenovirus replication and persistence in hypertrophic adenoids and palatine tonsils in children. Journal of medical virology. 2019;91(7):1250-1262. doi: 10.1002/jmv.25441</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Y, Jiao H, Mi C, Yang G, Han T. Evaluation of adenoid hypertrophy with ultrasonography. The Indian Journal of Pediatrics. 2020;87:910-915. doi: 10.1007/s12098-020-03203-4</mixed-citation><mixed-citation xml:lang="en">Wang Y, Jiao H, Mi C, Yang G, Han T. Evaluation of adenoid hypertrophy with ultrasonography. The Indian Journal of Pediatrics. 2020;87:910-915. doi: 10.1007/s12098-020-03203-4</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Samal DK, Nayak A, Adya AK. Laryngeal Lymphoid Hyperplasia Presenting as Stridor in Pediatric Age. Iranian Journal of Otorhinolaryngology. 2022;34(121):127. doi: 10.22038/IJORL.2021.58575.3024</mixed-citation><mixed-citation xml:lang="en">Samal DK, Nayak A, Adya AK. Laryngeal Lymphoid Hyperplasia Presenting as Stridor in Pediatric Age. Iranian Journal of Otorhinolaryngology. 2022;34(121):127. doi: 10.22038/IJORL.2021.58575.3024</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Roßberg W, Dagistani A, Mitovska D, Krüger C, Warnecke A, Lenarz T, Durisin M. Hypertrophy of lingual tonsil following tonsillectomy and correlation with BMI. Laryngo-Rhino-Otologie. 2022;102(5):357-363. doi: 10.1055/a-1887-6352</mixed-citation><mixed-citation xml:lang="en">Roßberg W, Dagistani A, Mitovska D, Krüger C, Warnecke A, Lenarz T, Durisin M. Hypertrophy of lingual tonsil following tonsillectomy and correlation with BMI. Laryngo-Rhino-Otologie. 2022;102(5):357-363. doi: 10.1055/a-1887-6352</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
