zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2024-21-1-03zdor-2692Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESНерешенные вопросы применения методов визуализации при COVID-19-ассоциированном поражении желудка и кишечникаUnresolved issues in the use of imaging techniques in COVID-19-associated lesions of the stomach intestinehttps://orcid.org/0000-0003-0808-183XЮрковскийА. М.YurkovskiyА. М.

Алексей Михайлович Юрковский, д. м. н., доцент, заведующий кафедрой

кафедра лучевой диагностики с курсом ФПКиП

Гомель

Аlexei М. Yurkovskiy, Doctor of Medical Sciences, Head of the Department

Department of Radiation Diagnostics with the course of Advanced Training and Retraining

Gomel

yurkovsky@mail.ruhttps://orcid.org/0000-0003-0059-194XБойкоМ. А.BoikaM. A.

Марина Александровна Бойко, ассистент

кафедра лучевой диагностики с курсом ФПКиП

Гомель

Maryna A. Boika, Assistant Lecturer

Department of Radiation Diagnostics with course of Advanced Training andRetraining

Gomel

marinazhuravlevabojko205@gmail.comГомельский государственный медицинский университетGomel State Medical University2024290320242112933Copyright © Юрковский А.М., Бойко М.А., 20242024Юрковский А.М., Бойко М.А.Yurkovskiy А.М., Boika M.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/2692   Цель исследования

   Цель исследования. Систематизировать и проанализировать данные о применении методов визуализации при COVID-19-ассоциированных поражениях желудка и кишечника.

   Материалы и методы

   Материалы и методы. Проведен анализ публикаций в системах PubMed, EMBASE и Web of Science в период 2020–2023 гг., описывающих случаи применения методов визуализации у пациентов с подтвержденным диагнозом COVID-19-ассоциированных поражений желудочно-кишечного тракта.

   Результаты

   Результаты. Определены наиболее часто встречающиеся при абдоминальной визуализации признаки COVID-19-ассоциированного поражения желудка и кишечника, оценена их инцидентность и ориентировочная диагностическая значимость.

   Заключение

   Заключение. Применение компьютерной томографии и ультрасонографии для диагностики COVID-19-ассоциированного поражения желудка и кишечника сдерживается отсутствием четких представлений относительно чувствительности, специфичности и прогностической ценности описанных ранее лучевых признаков поражения желудочно-кишечного тракта. Кроме того, отсутствует четкий алгоритм применения методов визуализации при COVID-19-ассоциированном абдоминальном болевом синдроме. Решение указанных вопросов позволит оптимизировать применение методов визуализации и сократить время диагностического поиска.

   Objective

   Objective. To systematize and analyze data on the use of imaging techniques in COVID-19-associated gastric and intestinal lesions.

   Materials and methods

   Materials and methods. An analysis of publications in PubMed, EMBASE and Web of Science systems was carried out in the period 2020-2023, describing the use of imaging techniques in patients with a confirmed diagnosis of COVID-19-associated gastrointestinal lesions.

   Results

   Results. The most frequent signs of COVID-19-associated gastric and intestinal lesions on abdominal imaging were identified, their incidence and approximate diagnostic significance were evaluated.

   Conclusion

   Conclusion. The use of computed tomography and ultrasonography for the diagnosis of COVID-19-associated gastrointestinal lesions is hampered by the lack of clear ideas regarding the sensitivity, specificity, and prognostic value of the previously described radiologic signs of gastrointestinal lesions. In addition, there is no clear algorithm for the use of imaging methods in COVID-19-associated abdominal pain syndrome. The solution of these issues will optimize the use of imaging methods and reduce the time of diagnostic search.

желудочно-кишечные проявления COVID-19абдоминальная визуализацияgastrointestinal manifestations in COVID-19abdominal imagingРабота выполнялась в рамках проекта НИР «Разработать алгоритм прогнозирования пост-COVID-19 ассоциированной патологии на основании изучения клинико-лабораторных и функциональных показателей», ГПНИ 4 «Трансляционная медицина», подпрограмма 4.2 «Фундаментальные аспекты медицинской науки». Сроки выполнения с 01. 01. 2022 по 31. 12. 2024The work was performed within the framework of the research project "To develop an algorithm for predictingpost-COVID-19 associated pathology based on the study of clinical, laboratory and functional parameters", State program of scientific research 4 "Translational Medicine", subprogram 4.2 "Fundamental Aspects of Medical Science". Due dates from 01. 01. 2022 to 31. 12. 2024ReferencesRodríguez-Lago I, Ramírez de la Piscina P, Elorza A, Merino О, de Zárate JO, Cabriada JL. Characteristics and prognosis of patients with inflammatory bowel disease during the SARS-CoV-2 pandemic in the Basque Country (Spain). Gastroenterology. 2020;159(2):781-783. doi: 10.1053/j.gastro.2020.04.043Rodríguez-Lago I, Ramírez de la Piscina P, Elorza A, Merino О, de Zárate JO, Cabriada JL. Characteristics and prognosis of patients with inflammatory bowel disease during the SARS-CoV-2 pandemic in the Basque Country (Spain). Gastroenterology. 2020;159(2):781-783. doi: 10.1053/j.gastro.2020.04.043Kariyawasam JC, Jayarajah U, Riza R, Abeysuriya V, Seneviratne SL. Gastrointestinal manifestations in COVID-19. Trans R Soc Trop Med Hyg. 2021;115(12):1362-1388. doi: 10.1093/trstmh/trab042Kariyawasam JC, Jayarajah U, Riza R, Abeysuriya V, Seneviratne SL. Gastrointestinal manifestations in COVID-19. Trans R Soc Trop Med Hyg. 2021;115(12):1362-1388. doi: 10.1093/trstmh/trab042Redd WD, Zhou JC, Hathorn KE, McCarty TR, Bazarbashi AN, Thompson CC, et al. Prevalence and characteristics of gastrointestinal symptoms in patients with severe acute respiratory syndrome coronavirus 2 infection in the United States: a multicenter cohort study. Gastroenterology. 2020;159(2):765-767. doi: 10.1053/j.gastro.2020.04.045Redd WD, Zhou JC, Hathorn KE, McCarty TR, Bazarbashi AN, Thompson CC, et al. Prevalence and characteristics of gastrointestinal symptoms in patients with severe acute respiratory syndrome coronavirus 2 infection in the United States: a multicenter cohort study. Gastroenterology. 2020;159(2):765-767. doi: 10.1053/j.gastro.2020.04.045Trottein F, Sokol H. Potential causes and consequences of gastrointestinal disorders during a SARS-CoV-2 infection. Cell Rep. 2020;32(3):107915. doi: 10.1016/j.celrep.2020.107915Trottein F, Sokol H. Potential causes and consequences of gastrointestinal disorders during a SARS-CoV-2 infection. Cell Rep. 2020;32(3):107915. doi: 10.1016/j.celrep.2020.107915Lin L, Jiang X, Zhang Z, Huang S, Zhang Z, Fang Z, et al. Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut. 2020;69(6):997-1001. doi: 10.1136/gutjnl-2020-321013Lin L, Jiang X, Zhang Z, Huang S, Zhang Z, Fang Z, et al. Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut. 2020;69(6):997-1001. doi: 10.1136/gutjnl-2020-321013Xiao F, Tang M, Zheng X, Liu Y, Li X, Shan H. Evidence for gastrointestinal infection of SARS-CoV-2. Gastroenterology. 2020;158(6):1831-1833.e3. doi: 10.1053/j.gastro.2020.02.055Xiao F, Tang M, Zheng X, Liu Y, Li X, Shan H. Evidence for gastrointestinal infection of SARS-CoV-2. Gastroenterology. 2020;158(6):1831-1833.e3. doi: 10.1053/j.gastro.2020.02.055Bhayana R, Som А, Li МD, Carey DE. Abdominal Imaging Findings in COVID-19: Preliminary Observations. Radiology. 2020; 297(1): E207-E215. doi: 10.1148/radiol.2020201908Bhayana R, Som А, Li МD, Carey DE. Abdominal Imaging Findings in COVID-19: Preliminary Observations. Radiology. 2020; 297(1): E207-E215. doi: 10.1148/radiol.2020201908Abdelmohsen MA, Alkandari BM, Gupta VK, ElBeheiry AA. Diagnostic value of abdominal sonography in confirmed COVID-19 intensive care patients. Egyptian Journal of Radiology and Nuclear Medicine. 2020;51(1):198 doi: 10.1186/s43055-020-00317-9Abdelmohsen MA, Alkandari BM, Gupta VK, ElBeheiry AA. Diagnostic value of abdominal sonography in confirmed COVID-19 intensive care patients. Egyptian Journal of Radiology and Nuclear Medicine. 2020;51(1):198 doi: 10.1186/s43055-020-00317-9Horvat N, Pinto PV, Araujo-Filho JD, Santos JM et al. Abdominal gastrointestinal imaging findings on computed tomography in patients with COVID-19 and correlation with clinical outcomes. Eur J Radiol Open. 2021;8:100326. doi: 10.1016/j.ejro.2021.100326Horvat N, Pinto PV, Araujo-Filho JD, Santos JM et al. Abdominal gastrointestinal imaging findings on computed tomography in patients with COVID-19 and correlation with clinical outcomes. Eur J Radiol Open. 2021;8:100326. doi: 10.1016/j.ejro.2021.100326Гриневич В.Б., Кравчук Ю.А. Болезни органов пищеварения и COVID-19. Известия Российской Военно-медицинской академии. 2021;40(3):39-44. doi: 10.17816/rmmar76269Grinevich VB, Kravchuk YuA. Diseases of the digestive organs and COVID-19. Russian Military Medical Academy Reports. 2021;40(3):39-44. (In Russ.). doi: 10.17816/rmmar76269Groff А, Kavanaugh М, Ramgobin D, McClafferty B, Aggarwal CS, Golamari R, et al. Gastrointestinal manifestations of COVID-19 : a review of what we know. Ochsner Journal. 2021; 21(2):177-180. doi: 10.31486/toj.20.0086Groff А, Kavanaugh М, Ramgobin D, McClafferty B, Aggarwal CS, Golamari R, et al. Gastrointestinal manifestations of COVID-19 : a review of what we know. Ochsner Journal. 2021; 21(2):177-180. doi: 10.31486/toj.20.0086D’Amico F, Baumgart DC, Danese S, Peyrin-Biroulet L. Diarrhea during COVID-19 infection: pathogenesis, epidemiology, prevention, and management. Clin Gastroenterol Hepatol. 2020;18(8):1663-1672. doi: 10.1016/j.cgh.2020.04.001D’Amico F, Baumgart DC, Danese S, Peyrin-Biroulet L. Diarrhea during COVID-19 infection: pathogenesis, epidemiology, prevention, and management. Clin Gastroenterol Hepatol. 2020;18(8):1663-1672. doi: 10.1016/j.cgh.2020.04.001Goldberg-Stein S, Fink A, Paroder V, Kobi M, Yee J, Chernyak V. Abdominopelvic CT findings in patients with novel coronavirus disease 2019 (COVID-19). Abdom Radiol. 2020;45(9):2613-2263. doi: 10.1007/s00261-020-02669-2Goldberg-Stein S, Fink A, Paroder V, Kobi M, Yee J, Chernyak V. Abdominopelvic CT findings in patients with novel coronavirus disease 2019 (COVID-19). Abdom Radiol. 2020;45(9):2613-2263. doi: 10.1007/s00261-020-02669-2Singh P, Singh SP, Verma AK, Raju SN, Parihar A. A Systematic Review of abdominal imaging findings in COVID-19 patients. Visc Med. 2021;37(6):521-532. doi: 10.1159/000518473Singh P, Singh SP, Verma AK, Raju SN, Parihar A. A Systematic Review of abdominal imaging findings in COVID-19 patients. Visc Med. 2021;37(6):521-532. doi: 10.1159/000518473Shiralkar K, Chinapuvvula N, Ocazionez D. Cross-Sectional abdominal imaging findings in patients with COVID-19. Cureus. 2020;12(8): e9538 doi: 10.7759/cureus.9538Shiralkar K, Chinapuvvula N, Ocazionez D. Cross-Sectional abdominal imaging findings in patients with COVID-19. Cureus. 2020;12(8): e9538 doi: 10.7759/cureus.9538Balaban DV, Baston OM, Jinga M. Abdominal imaging in COVID-19. World J Radiol. 2021;13(7):227-232. doi: 10.4329/wjr.v13.i7.227Balaban DV, Baston OM, Jinga M. Abdominal imaging in COVID-19. World J Radiol. 2021;13(7):227-232. doi: 10.4329/wjr.v13.i7.227Patel RK, Chandel K, Mittal S, Tripathy T. Abdominal computed tomography findings among COVID-19 patients with index gastrointestinal manifestations: a preliminary single-center experience. Euroasian J Hepatogastroenterol. 2021;11(2):76-80. doi: 10.5005/jp-journals-10018-1346Patel RK, Chandel K, Mittal S, Tripathy T. Abdominal computed tomography findings among COVID-19 patients with index gastrointestinal manifestations: a preliminary single-center experience. Euroasian J Hepatogastroenterol. 2021;11(2):76-80. doi: 10.5005/jp-journals-10018-1346Mavropoulou X, Psoma E, Papachristodoulou F, Pyrrou N, Spanou E, Alexandratou M, et al. Gastrointestinal imaging findings in the era of COVID-19: A Pictorial Review. Medicina. 2023;59(7):1332. doi: 10.3390/medicina59071332Mavropoulou X, Psoma E, Papachristodoulou F, Pyrrou N, Spanou E, Alexandratou M, et al. Gastrointestinal imaging findings in the era of COVID-19: A Pictorial Review. Medicina. 2023;59(7):1332. doi: 10.3390/medicina59071332Parry AH, Wani AH, Yaseen M. Acute Mesenteric Ischemia in Severe Coronavirus-19 (COVID-19): possible mechanisms and diagnostic pathway. Acad Radiol. 2020;27(8):1190. doi: 10.1016/j.acra.2020.05.016Parry AH, Wani AH, Yaseen M. Acute Mesenteric Ischemia in Severe Coronavirus-19 (COVID-19): possible mechanisms and diagnostic pathway. Acad Radiol. 2020;27(8):1190. doi: 10.1016/j.acra.2020.05.016Cheung S, Quiwa JC, Pillai A, Onwu C, Tharayil ZJ, Gupta R. Superior mesenteric artery thrombosis and acute intestinal ischemia as a consequence of COVID-19 Infection. Am J Case Rep. 2020;21:e925753-1-e925753-3. doi: 10.12659/AJCR.925753Cheung S, Quiwa JC, Pillai A, Onwu C, Tharayil ZJ, Gupta R. Superior mesenteric artery thrombosis and acute intestinal ischemia as a consequence of COVID-19 Infection. Am J Case Rep. 2020;21:e925753-1-e925753-3. doi: 10.12659/AJCR.925753Pan L, Mu M, Yang P., Sun Y. et al. Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study. Am. J. Gastroenterol. 2020;115:766-773. doi: 10.14309/ajg.0000000000000620Pan L, Mu M, Yang P., Sun Y. et al. Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study. Am. J. Gastroenterol. 2020;115:766-773. doi: 10.14309/ajg.0000000000000620Юрковский А.М., Бойко М.А., И. В. Назаренко, С. Л. Ачинович, И.О. Стома COVID-19-ассоциированные изменения желудочно-кишечного тракта: сопоставление данных ультразвуковых и морфологических исследований (пилотное исследование). Лучевая диагностика и терапия. 2022;13(3):36-44. doi: 10.22328/2079-5343-2022-13-3-58-66Yurkovskiy А.М., Boyko М.А., Nazarenko I.V., Achinovich S.L., Stoma I.O. COVID-19-associated changes in the gastrointestinal tract: a comparison of ultrasound and morphological data : a pilot study. Diagnostic radiology and radiotherapy. 2022;13(3):36-44. (In Russ.). doi: 10.22328/2079-5343-2022-13-3-58-66Lu C, Ma C, Ingram RJM, Chan M et al. Innovative care for inflammatory bowel disease patients during the COVID-19 pandemic: use of bedside intestinal ultrasound to optimize management. Journal of the Canadian Association of Gastroenterology. 2023;6(1): e1-e6. doi: 10.1093/jcag/gwac006Lu C, Ma C, Ingram RJM, Chan M et al. Innovative care for inflammatory bowel disease patients during the COVID-19 pandemic: use of bedside intestinal ultrasound to optimize management. Journal of the Canadian Association of Gastroenterology. 2023;6(1): e1-e6. doi: 10.1093/jcag/gwac006

The authors declare that there are no conflicts of interest present.