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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2023-20-4-03</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2639</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Саркопения: особенности проявления у пациентов с сахарным диабетом</article-title><trans-title-group xml:lang="en"><trans-title>Sarcopenia: features of manifestation in patients with diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7033-719X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Навменова</surname><given-names>Я. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Naumenava</surname><given-names>Ya. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Навменова Яна Леонидовна, к.м.н., доцент, доцент кафедры внутренних болезней № 1 с курсами эндокринологии и гематологии; заведующий отделением эндокринологии</p><p>Гомель</p></bio><bio xml:lang="en"><p>Yana L. Naumenava, Candidate of Medical Sciences, Associate Professor at thе Department of Internal Diseases No.1 with the Courses of Endocrinology and Hematology; Head of the Department for Endocrinology</p><p>Gomel</p></bio><email xlink:type="simple">yano4ka.n@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1251-1962</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махлина</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Makhlina</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Махлина Елена Семеновна, к.м.н., доцент, доцент кафедры внутренних болезней № 1 с курсами эндокринологии и гематологии</p><p>Гомель</p></bio><bio xml:lang="en"><p>Alena S. Makhlina, Candidate of Medical Sciences, Associate Professor at thе Department of Internal Diseases No.1 with the Courses of Endocrinology and Hematology</p><p>Gomel</p></bio><email xlink:type="simple">mahlina.elena@yandex.by</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7496-6164</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гавриленко</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Haurylenka</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гавриленко Дмитрий Иванович, к.м.н., заведующий отделением функциональной диагностики</p><p>Гомель</p></bio><bio xml:lang="en"><p>Dzmitry I. Haurylenka, Candidate of Medical Sciences, Head of the Department of Functional Diagnostics</p><p>Gomel</p></bio><email xlink:type="simple">dm.gavrilenko891@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-8333-6254</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бортновская</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bartnovskaya</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бортновская Мария Николаевна, врач-эндокринолог</p><p>Гомель</p></bio><bio xml:lang="en"><p>Maryia N. Bartnovskaya, Endocrinologist</p><p>Gomel</p></bio><email xlink:type="simple">mbortnovskaya@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-6967-6589</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демьяненко</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Demyanenko</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Демьяненко Илона Николаевна, заведующий приемным отделением</p><p>Гомель</p></bio><bio xml:lang="en"><p>Ilona N. Demyanenko, Head of the Admissions Department</p><p>Gomel</p></bio><email xlink:type="simple">ilona_Demyanenko@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет; Республиканский научно-практический центр радиационной медицины и экологии человека»</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University; Republican Scientific and Practical Center for Radiation Medicine and Human Ecology</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Республиканский научно-практический центр радиационной медицины и экологии человека</institution></aff><aff xml:lang="en"><institution>Republican Scientific and Practical Center for Radiation Medicine and Human Ecology</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Гомельский областной эндокринологический диспансер</institution></aff><aff xml:lang="en"><institution>Gomel Regional Endocrinological Dispensary</institution></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Гомельская городская клиническая больница скорой медицинской помощи</institution></aff><aff xml:lang="en"><institution>Gomel City Clinical Emergency Hospital</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>03</day><month>01</month><year>2024</year></pub-date><volume>20</volume><issue>4</issue><elocation-id>26–34</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Навменова Я.Л., Махлина Е.С., Гавриленко Д.И., Бортновская М.Н., Демьяненко И.Н., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Навменова Я.Л., Махлина Е.С., Гавриленко Д.И., Бортновская М.Н., Демьяненко И.Н.</copyright-holder><copyright-holder xml:lang="en">Naumenava Y.L., Makhlina A.S., Haurylenka D.I., Bartnovskaya M.N., Demyanenko I.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2639">https://journal.gsmu.by/jour/article/view/2639</self-uri><abstract><p>Цель исследования. Провести оценку параметров саркопении (СП) и факторов, влияющих на них, у пациентов с сахарным диабетом (СД).Материалы и методы. Проведено исследование 87 госпитализированных пациентов с СД (29 мужчин — 33 % и 58 женщин — 67 %) в возрасте от 21 до 61 года. Исследование включало определение клинико-лабораторных показателей, включая антропометрические данные, лабораторные показатели, определение параметров саркопении (мышечная масса, мышечная сила, мышечная функция), ультразвуковое исследование скелетных мышц. Результаты. Снижение мышечной массы отмечено у 11 % пациентов с СД и зависит от композиционного состава тела. Снижение мышечной функции отмечено у 30 % пациентов с СД и зависит от возраста пациента (более 41 года; AUS — 0,826; р &lt; 0,001) и степени избытка массы тела (у 87 % пациентов ИМТ более 30 кг/м2). Снижение мышечной силы отмечено у 44 % пациентов и зависит от степени выраженности диабетической нейропатии (более 1 балла по результатам шкалы NDSm; AUS — 0,876; р &lt; 0,001). Окружность голени положительно взаимосвязана с толщиной промежуточной широкой мышцы бедра (r = 0,44; р &lt; 0,05) и толщиной кожно-мышечной складки (r = 0,70; р &lt; 0,05), определенными с помощью ультразвуковой методики.Заключение. Вероятность СП отмечена у 44 % пациентов с СД и зависит от стажа СД и степени выраженности диабетической нейропатии. Мышечная функция снижена у 30 % пациентов с СД и связана с возрастом пациента и избыточным весом. Снижение мышечной массы отмечено у 11 % пациентов с СД и зависит от композиционного состава тела. Толщина промежуточной широкой мышцы бедра и толщина кожно-мышечной складки на уровне бедра (по результатам УЗИ) достоверно взаимосвязаны с мышечной массой.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To evaluate the parameters of sarcopenia (SP) and the factors affecting them in patients with diabetes mellitus (DM).Materials and methods. A study of 87 hospitalized patients with DM (29 men — 33% and 58 women — 67%) aged 21 to 61 years was conducted. The study included the determination of clinical and laboratory parameters, including anthropometric data, laboratory parameters, determination of sarcopenia parameters (muscle mass, muscle strength, muscle function), ultrasound examination of skeletal muscles.Results. A decrease in muscle mass was observed in 11% of patients with DM and depends on the composition of the body. A decrease in muscle function was observed in 30% of patients with DM and depends on the patient’s age (over 41 years; AUS — 0.826; p &lt; 0.001) and the degree of excess body weight (in 87% of patients, BMI is more than 30 kg/m2). A decrease in muscle strength was noted in 44% of patients and depends on the severity of diabetic neuropathy (more than 1 point according to the results of the NDSm scale; AUS — 0.876; p &lt; 0.001). The circumference of the lower leg is positively correlated with the thickness of the intermediate broad thigh muscle (rs = 0.44; p &lt; 0.05) and the thickness of the musculoskeletal fold (rs = 0.70; p &lt; 0.05), determined by ultrasound technique.Conclusion. The probability of SP was noted in 44% of patients with DM and depends on the length of DM and the severity of diabetic neuropathy. Muscle function is reduced in 30% of patients with DM and is associated with the patient’s age and overweight. A decrease in muscle mass was observed in 11% of patients with DM and depends on the composition of the body. The thickness of the intermediate broad thigh muscle and the thickness of the musculoskeletal fold at the hip level (according to ultrasound results) are significantly interrelated with muscle mass.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>саркопения</kwd><kwd>мышечная масса</kwd><kwd>мышечная сила</kwd><kwd>мышечная функция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes</kwd><kwd>sarcopenia</kwd><kwd>muscle mass</kwd><kwd>muscle strength</kwd><kwd>muscle function</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Авторы выражают благодарность директору ГУ «Республиканский научно-практический центр радиационной медицины и экологии человека» А. В. Рожко, заведующему клинико-диагностической лабораторией ГУ «Республиканский научно-практический центр радиационной медицины и экологии человека» Ю. И. 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