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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2023-20-3-02</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2583</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Клинико-психологические особенности пациентов с алкогольной зависимостью при формировании терапевтической ремиссии высокого качества</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and psychological characteristics of alcohol-dependent patients in the formation of high quality therapeutic remission</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6343-3773</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сквира</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Skvira</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сквира Иван Михайлович, д.м.н., доцент, заведующий курсом психиатрии кафедры неврологии и нейрохирургии с курсами медицинской реабилитации, психиатрии и ФПКиП</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Ivan M. Skvira, Doctor of Medical Sciences, Associate Professor, Head of the Psychiatry course of the Department of Neurology and Neurosurgery with courses of Medical Rehabilitation, Psychiatry, Faculty of Advanced Training and Retraining</p><p>Gomel</p></bio><email xlink:type="simple">imskvira@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-5537-9018</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сквира</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Skvira</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сквира Михаил Иванович, магистр психологии, ассистент курса психиатрии кафедры неврологии и нейрохирургии с курсами медицинской реабилитации, психиатрии и ФПКиП</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Mikhail I. Skvira, Master of Psychology, Psychiatry course Assistant, Department of Neurology and Neurosurgery with courses of Medical Rehabilitation, Psychiatry, Faculty of Advanced Training and Retraining</p><p>Gomel</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9326-0551</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абрамов</surname><given-names>Б. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Abramov</surname><given-names>B. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Абрамов Борис Эвильевич, ассистент курса психиатрии кафедры неврологии и нейрохирургии с курсами медицинской реабилитации, психиатрии и ФПКиП</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Boris E. Abramov, Assistant of the course of Psychiatry, Department of Neurology and Neurosurgery with courses of Medical Rehabilitation, Psychiatry, Faculty of Advanced Training and Retraining</p><p>Gomel</p></bio><email xlink:type="simple">psychiatry@gsmu.by</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>25</day><month>09</month><year>2023</year></pub-date><volume>20</volume><issue>3</issue><fpage>13</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сквира И.М., Сквира М.И., Абрамов Б.Э., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Сквира И.М., Сквира М.И., Абрамов Б.Э.</copyright-holder><copyright-holder xml:lang="en">Skvira I.M., Skvira M.I., Abramov B.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2583">https://journal.gsmu.by/jour/article/view/2583</self-uri><abstract><p>Цель исследования. Выявить клинико-психологические особенности, способствующие становлению терапевтической ремиссии у пациентов с алкогольной зависимостью (ПАЗ).Материалы и методы. Проведено комплексное (клиническое, экспериментально-психологическое, статистическое) сравнительное исследование 79 ПАЗ на этапе становления терапевтической ремиссии (из них 39 человек в ремиссии высокого качества и 40 — в ремиссии низкого качества) и 42 практически здоровых лиц в возрасте от 27 до 55 (40,18 ± 10,2) лет.Результаты. Установлено, что состояние ПАЗ в ремиссии высокого качества отличалось от состояния пациентов с угрозой рецидива и здоровых лиц достоверно меньшим количеством жалоб на здоровье (p &lt; 0,05), более высокими показателями психологического функционирования (p &lt; 0,01) и высоким уровнем активации неспецифической адаптационной реакции организма (НАРО) (p &lt; 0,001).Заключение. Для становления качественной и длительной терапевтической ремиссии у ПАЗ требуется не только специфические изменения с ослаблением проявлений болезни, но и высокий уровень НАРО, обеспечивающий энергетическое поддержание процесса выздоровления с интеграцией в здоровое общество.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To identify clinical and psychological features that contribute to the formation of therapeutic remission in patients with alcohol dependence (PAD).Materials and methods. A comprehensive (clinical, experimental, psychological, statistical) comparative study was conducted of 79 PAD at the stage of therapeutic remission (icnluding 39 people in high-quality remission and 40 in low-quality remission) and 42 practically healthy individuals aged 27 to 55 (40.18 ± 10.2) years.Results. It was found that the condition of patients with high-quality PAD in remission differed from the condition of patients with the threat of relapse and healthy individuals with significantly fewer health complaints (p &lt; 0.05), higher indicators of psychological functioning (p &lt; 0.01) and a high level of activation of the nonspecific adaptive reaction of the body (NARB) (p &lt; 0.001).It was found that the state of PAD in high remission differed from that of patients at risk of relapse and healthy individuals by a significantly lower number of health complaints (p &lt; 0.05), higher indicators of psychological functioning (p &lt; 0.01) and a high level of activation of nonspecific adaptive response of the body (NARB) (p &lt; 0.001).Conclusion. The formation of qualitative and long-term therapeutic remission in PAD requires not only specific changes with a weakening of the manifestations of the disease, but also a high level of NARB, which provides energy support for the process of recovery with integration into a healthy society.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>алкогольная зависимость</kwd><kwd>ремиссия</kwd><kwd>рецидивоопасные клинические ситуации</kwd><kwd>неспецифическая адаптационная реакция организма</kwd></kwd-group><kwd-group xml:lang="en"><kwd>alcohol dependence</kwd><kwd>remission</kwd><kwd>relapse-dangerous clinical situations</kwd><kwd>nonspecific adaptive reaction of the body</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Максимчук В.П., Копытов А.В. Оценка уровня алкоголизации населения в различных регионах Республики Беларусь. 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