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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2023-20-2-16</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2558</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Коррекция истмико-цервикальной недостаточности при пролабировании плодного пузыря и внутриматочной инфекции</article-title><trans-title-group xml:lang="en"><trans-title>Correction of cervical insufficiency during prolapse of the fetal bladder and intrauterine infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0718-8881</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захаренкова</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharenkova</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захаренкова Татьяна Николаевна, к.м.н., доцент, заведующий кафедрой акушерства и гинекологии с курсом ФПКиП</p><p>Гомель</p></bio><bio xml:lang="en"><p>Tatsiana N. Zakharenkova, Candidate of Medical Scinces, Head of the Department of Obstetrics and Gynecology with the Course of FPDR</p><p>Gomel</p></bio><email xlink:type="simple">tera03@yadex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5325-4368</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кругликова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kruglikova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кругликова Анна Викторовна, врач акушер-гинеколог</p><p>Гомель</p></bio><bio xml:lang="en"><p>Anna V. Kruglikova, Gynecologist</p><p>Gomel</p></bio><email xlink:type="simple">ann-krug@yandex.by</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0193-6380</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воронкова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Voronkova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Воронкова Елизавета Андреевна, врач акушер-гинеколог</p><p>Гомель</p></bio><bio xml:lang="en"><p>Elizabeth A. Voronkova, Gynecologist</p><p>Gomel</p></bio><email xlink:type="simple">hajluk@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Гомельская городская клиническая больница № 3</institution></aff><aff xml:lang="en"><institution>Gomel City Clinical Hospital No. 3</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>07</month><year>2023</year></pub-date><volume>20</volume><issue>2</issue><fpage>128</fpage><lpage>134</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Захаренкова Т.Н., Кругликова А.В., Воронкова Е.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Захаренкова Т.Н., Кругликова А.В., Воронкова Е.А.</copyright-holder><copyright-holder xml:lang="en">Zakharenkova T.N., Kruglikova A.V., Voronkova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2558">https://journal.gsmu.by/jour/article/view/2558</self-uri><abstract><p>В статье описывается клинический случай течения и ведения беременности, осложненной истмико-цервикальной недостаточностью с пролабированием плодного пузыря и формированием «сладжа» в околоплодных водах у первобеременной пациентки на сроке 20–21 неделя. Поэтапное применение антибактериальной терапии и гормональной поддержки микронизированным прогестероном, последующий хирургический серкляж и установка разгружающего акушерского пессария позволили пролонгировать беременность до 284 дней и родоразрешить женщину через естественные родовые пути новорожденным без признаков внутриутробной инфекции.</p></abstract><trans-abstract xml:lang="en"><p>This article describes a clinical case of the course and management of pregnancy complicated by cervical insufficiency with prolapse of the fetal bladder and formation of “sludge” in the amniotic fluid at 20–21 weeks of pregnancy. Gradual use of antibacterial therapy and hormonal support with micronized progesterone, subsequent surgical serclage and the installation of an unloading obstetric pessary allowed to prolong pregnancy to 284 days and to deliver through the natural birth canal with a newborn without signs of intrauterine infection.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>невынашивание беременности</kwd><kwd>истмико-цервикальная недостаточность</kwd><kwd>пролабирование плодного пузыря</kwd><kwd>хирургическая коррекция истмико-цервикальной недостаточности</kwd><kwd>внутриматочная инфекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>miscarriage</kwd><kwd>cervical insufficiency</kwd><kwd>prolapse of the fetal bladder</kwd><kwd>surgical correction of cervical insufficiency</kwd><kwd>intrauterine infection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mönckeberg M, Valdés R, Kusanovic J, Schepeler M, Nien J, Pertossi E et al. Patients with acute cervical insufficiency without intra-amniotic infection/inflammation treated with cerclage have a good prognosis. Journal of Perinatal Medicine. 2019;47(5):500-509. DOI: https://doi.org/10.1515/jpm-2018-0388</mixed-citation><mixed-citation xml:lang="en">Mönckeberg M, Valdés R, Kusanovic J, Schepeler M, Nien J, Pertossi E et al. Patients with acute cervical insufficiency without intra-amniotic infection/inflammation treated with cerclage have a good prognosis. Journal of Perinatal Medicine. 2019;47(5):500-509. DOI: https://doi.org/10.1515/jpm-2018-0388</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Долгушина В.Ф., Курносенко И.В., Алиханова Е.С., Семёнов Ю.А. Цервико-вагинальные инфекции при истмикоцервикальной недостаточности. Доктор.Ру. 2021;20(1):61-67. DOI: https://doi.org/10.31550/1727-2378-2021-20-1-61-67</mixed-citation><mixed-citation xml:lang="en">Dolgushina VF, Kurnosenko IV, Alihanova ES, Semyonov YuA. Cervical and Vaginal Infections in Insuficiencia Istmicocervical. Doktor.Ru. 2021;20(1):61-67. (In Russ.). DOI: https://doi.org/10.31550/1727-2378-2021-20-1-61-67</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Рухляда Н.Н., Тайц А.Н., Романова Л.А., Матухин В.И., Логунова М.А., Сабыржанова К.А. Бактериальный вагиноз как фактор риска преждевременных родов. Педиатр. 2019;10(4):97-101. DOI: https://doi.org/10.17816/PED10497-101</mixed-citation><mixed-citation xml:lang="en">Ruhlyada NN, Tajc AN, Romanova LA, Matuhin VI, Logunova MA, Sabyrzhanova KA. Bacterial vaginosis as a risk factor for preterm birth. Pediatr. 2019;10(4):97-101. (In Russ.). DOI: https://doi.org/10.17816/PED10497-101</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Mercer BM, Goldenberg RL, Moawad AH, Meis PJ, Iams JD, Das AF et al. The preterm prediction study: effect of gestational age and cause of preterm birth on subsequent obstetric outcome. Am J Obstet Gynecol. 1999;181(5):1216-1221. DOI: https://doi.org/10.1016/s0002-9378(99)70111-0</mixed-citation><mixed-citation xml:lang="en">Mercer BM, Goldenberg RL, Moawad AH, Meis PJ, Iams JD, Das AF et al. The preterm prediction study: effect of gestational age and cause of preterm birth on subsequent obstetric outcome. Am J Obstet Gynecol. 1999;181(5):1216-1221. DOI: https://doi.org/10.1016/s0002-9378(99)70111-0</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Souka AP, Papastefanou I, Pilalis A, Kassanos D, Papadopoulos G. Implementation of universal screening for preterm delivery by mid-trimester cervical-length measurement. Ultrasound Obstet Gynecol. 2019 Mar;53(3):396-401. DOI: https://doi.org/10.1002/uog.19050</mixed-citation><mixed-citation xml:lang="en">Souka AP, Papastefanou I, Pilalis A, Kassanos D, Papadopoulos G. Implementation of universal screening for preterm delivery by mid-trimester cervical-length measurement. Ultrasound Obstet Gynecol. 2019 Mar;53(3):396-401. DOI: https://doi.org/10.1002/uog.19050</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Захаренкова Т.Н. Тактика ведения беременности со сладжем в околоплодных водах. Охрана материнства и детства. 2022;2(40):23-28.</mixed-citation><mixed-citation xml:lang="en">Zakharenkova TN. Management of pregnancy with amniotic fluid sludge. Ohrana materinstva i detstva. 2022;2(40):23-28. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">ACOG Practice Bulletin №142. Cerclage for the management of cervical insufficiency. Obstet Gynecol. 2014 Feb;123(2 Pt 1):372-379. DOI: https://doi.org/10.1097/01.AOG.0000443276.68274.cc</mixed-citation><mixed-citation xml:lang="en">ACOG Practice Bulletin №142. Cerclage for the management of cervical insufficiency. Obstet Gynecol. 2014 Feb;123(2 Pt 1):372-379. DOI: https://doi.org/10.1097/01.AOG.0000443276.68274.cc</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Wood AM, Dotters-Katz SK, Hughes BL. Cervical Cerclage versus Vaginal Progesterone for Management of Short Cervix in Low-Risk Women. Am J Perinatol. 2019 Jan;36(2):111-117. DOI: https://doi.org/10.1055/s-0038-1668547</mixed-citation><mixed-citation xml:lang="en">Wood AM, Dotters-Katz SK, Hughes BL. Cervical Cerclage versus Vaginal Progesterone for Management of Short Cervix in Low-Risk Women. Am J Perinatol. 2019 Jan;36(2):111-117. DOI: https://doi.org/10.1055/s-0038-1668547</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Рыбников С.В., Неретин А.К., Рудаева Е.В., Пачгин И.В., Мозес В.Г., Елгина С.И., Ошлыкова А.М. Ведение пациентки с пролабированием плодного пузыря при истмикоцервикальной недостаточности (клинический случай). Мать и дитя в Кузбассе. 2021;3(86):107-110. DOI: https://doi.org/10.24412/2686-7338-2021-3-107-110</mixed-citation><mixed-citation xml:lang="en">Rybnikov SV, Neretin AK, Rudaeva EV, Pachgin IV, Mozes VG, Elgina SI, Oshlykova AM. Management of a patient with fruit bladder in isthmic-cervical insufficiency (clinical case). Mat i ditya v Kuzbasse. 2021;3(86):107-110. (In Russ.). DOI: https://doi.org/10.24412/2686-7338-2021-3-107-110</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Shivani D, Quek BH, Tan PL, Shephali T. Does rescue cerclage work? J. Perinat Med. 2018;46(8): 876-880. DOI: https://doi.org/10.1515/jpm-2017-0311</mixed-citation><mixed-citation xml:lang="en">Shivani D, Quek BH, Tan PL, Shephali T. Does rescue cerclage work? J. Perinat Med. 2018;46(8): 876-880. DOI: https://doi.org/10.1515/jpm-2017-0311</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Цхай В.Б., Дудина АЮ., Кочетова Е.А., Лобанова Т.Т., Реодько С.В., Михайлова А.В. и др. Сравнительный анализ эффективности хирургической и консервативной тактики у беременных с истмико-цервикальной недостаточностью при пролабировании плодного пузыря. Акушерство и гинекология. 2019;(6):63-69. DOI: https://doi.org/10.18565/aig.2019.6.63-69</mixed-citation><mixed-citation xml:lang="en">Chaj VB, Dudina AYu, Kochetova EA, Lobanova TT, Reodko SV, Mihajlova AV, et al. Comparative analysis of the effectiveness of surgical and conservative tactics in pregnant women with isthmic-ocervical insufficiency for fetal bladder prolapse. Akusherstvo i ginekologiya. 2019;(6):63-69. (In Russ.). DOI: https://doi.org/10.18565/aig.2019.6.63-69</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Тетруашвили Н.К., Агаджанова А.А., Милушева А.К. Экстренный серкляж: показания, противопоказания, возможности медикаментозного лечения. Доктор.Ру. 2019;11(166):11-13. DOI: https://doi.org/10.31550/1727-2378-2019-166-11-11-13</mixed-citation><mixed-citation xml:lang="en">Tetruashvili NK, Agadzhanova AA, Milusheva AK. Emergency serclage: indications, contraindications, and medication options. Doktor.Ru. 2019;11(166):11-13. (In Russ.). DOI: https://doi.org/10.31550/1727-2378-2019-166-11-11-13</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Lee K-N, Park KH, Kim YM, Cho I, Kim TE. Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid. PLoS One. 2022 May 10;17(5):e0268291. DOI: https://doi.org/10.1371/journal.pone.0268291</mixed-citation><mixed-citation xml:lang="en">Lee K-N, Park KH, Kim YM, Cho I, Kim TE. Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid. PLoS One. 2022 May 10;17(5):e0268291. DOI: https://doi.org/10.1371/journal.pone.0268291</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
