zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2023-20-2-05zdor-2547Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEЗначимость идентификации патогена для инфекции мочевыводящих путей и Helicobacter pylori) инфекции у пациентов с сахарным диабетом 1 и 2 типаSignificance of pathogen identification for urinary tract infection and Helicobacter pylori infection in type 1 and type 2 diabetes mellitus patientshttps://orcid.org/0000-0003-4074-8657РусаленкоМ. Г.RusalenkoM. G.

Русаленко Мария Григорьевна, к.м.н., доцент,  заместитель директора

Гомель

Mariya G. Rusalenko, Candidate of Medical Sciences, Associate Professor, Deputy Director

Gomel

mgrusalenko@list.ruhttps://orcid.org/0000-0002-4148-4414ВишамМ.WishamM.

Мохамед Вишам, врач-эндокринолог

Гомель

Mohamed Wisham, Endocrinologist

Gomel

dr.vishams@gmail.comhttps://orcid.org/0000-0001-8405-0563КоноваловаТ. В.KonovalovaT. V.

Коновалова Татьяна Владимировна, врач-эндокринолог

Гомель

Tatiana V. Konovalova, Endocrinologist

Gomel

tatanaskubakova2@gmail.comhttps://orcid.org/0000-0002-0023-6713ЛыщенкоЛ. В.LischenkoL. V.

Лыщенко Любовь Валерьевна, врач-эндокринолог

Калинковичи;

клинический ординатор

Гомель

Lubov V. Lischenko, Endocrinologist

Kalinkovichi;

Clinical Resident

Gomel

Lyuba.domanchuk@mail.ruhttps://orcid.org/0000-0002-5722-6946СавастееваИ. Г.SavasteevaI. G.

Савастеева Ирина Георгиевна, врач-методист,  заведующий отделением Государственного регистра

Гомель

Irina G. Savasteeva, MD, Methodologist, Head of the  Department of State Registration

Gomel

savsatteeva69@gmail.comhttps://orcid.org/0000-0003-0579-6215ШевченкоН. И.ShevchenkoN. I.

Шевченко Наталья Ивановна, к.м.н., доцент, заведующая лабораторией клеточных технологий

Гомель

Natalia I. Shevchenko, Candidate of Medical Sciences, Associate Professor, Head of the Cell Technology  Laboratory

Gomel

shevchenkoni@bk.ruРеспубликанский научно-практический центр радиационной медицины и экологии человекаRepublican Research Center for Radiation Medicine and Human EcologyГомельская городская клиническая поликлиника № 11Gomel City Clinical Polyclinic №11Калинковичская центральная районная больница; Гомельский государственный медицинский университетKalinkovichi Central District Hospital; Gomel State Medical University2023100720232023541Copyright © Русаленко М.Г., Вишам М., Коновалова Т.В., Лыщенко Л.В., Савастеева И.Г., Шевченко Н.И., 20232023Русаленко М.Г., Вишам М., Коновалова Т.В., Лыщенко Л.В., Савастеева И.Г., Шевченко Н.И.Rusalenko M.G., Wisham M., Konovalova T.V., Lischenko L.V., Savasteeva I.G., Shevchenko N.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/2547

Цель исследования. Изучить значимость идентификации патогена инфекции мочевыводящих путей и Helicobacter pylori инфекции у пациентов с сахарным диабетом 1 и 2 типа.Материалы и методы. Изучены данные 1749 пациентов с сахарным диабетом 1 и 2 типа. Проведена оценка распространенности инфекции мочевыводящих путей, идентификации патогенов и их чувствительности к антибактериальным средствам с использованием микробиологического метода. Изучены данные верификации Helicobacter pylori инфекции методом ПЦР в биоптате слизистой желудка.Результаты. Установлено, что инфекция мочевыводящих путей имеет высокую распространенность у пациентов с сахарным диабетом: 58,3 % — при сахарном диабете 1 типа и 47,2 % — при сахарном диабете 2 типа. Выделены основные возбудители инфекции мочевыводящих путей: Escherichia coli, Staphylococcus saprophyticus, Enterococcus faecalis и Klebsiella pneumoniae. Выявлена более высокая распространенность Helicobacter pylori инфекции при сахарном диабете 2 типа (27,1 %), чем при сахарном диабете 1 типа (22,8 %). 5,9 % пациентов с сахарным диабетом 2 типа имели сочетанную инфекцию мочевыводящих путей и Helicobacter pylori инфекцию.Заключение. Исследование продемонстрировало высокую клиническую значимость идентификации патогена инфекции мочевыводящих путей и Helicobacter pylori инфекции при сахарном диабете, особенно у пациентов с сахарным диабетом 2 типа.

Objective. The aim of this study was to understand the significance of pathogen identification for Urinary tract infection and Helicobacter pylori infection in Diabetes Mellitus Type 1 and Diabetes Mellitus Type 2 patients.Materials and methods. The study was conducted among 1749 patients with Type 1 and Type 2 Diabetes Mellitus. Using microbiological techniques, the frequency of urinary tract infection was identified and the aetiology and sensitivity of microorganisms to antibacterial drugs were assessed. Data collected on Helicobacter pylori infection were verified through PCR tests on biopsies collected from the gastric mucosa.Results. The study showed that urinary tract infection has a high incidence rate with 58.3% of cases from Type 1 diabetes mellitus, and in 47.2% of cases from Type 2 diabetes. Pathogens such as Escherichia coli, Staphylococcus saprophyticus, Enterococcus faecalis and Klebsiella pneumoniae were the main causative agents of urinary tract infections. Helicobacter pylori infection was common in DM and more in cases of Type 2 Diabetes Mellitus at 27.1%, compared to cases in Type 1 Diabetes Mellitus at 22.8%. Also 5.9 % cases of Type 2 Diabetes Mellitus had combined Helicobacter pylori and urinary tract infections.Conclusion. The study showed the significance in identification of urinary tract infections and Helicobacter pylori infections in patients with Type 1 and Type 2 Diabetes Mellitus, and especially significant for Type 2 Diabetes Mellitus patients.

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The authors declare that there are no conflicts of interest present.