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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2023-20-2-01</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2543</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Диагностические стигмы алкогольной болезни печени</article-title><trans-title-group xml:lang="en"><trans-title>Diagnostic stigmas of alcoholic liver disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3705-7740</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Першенкова</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pershenkova</surname><given-names>O. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Першенкова Ольга Сергеевна, ассистент кафедры  общей и клинической фармакологии</p><p>Гомель</p></bio><bio xml:lang="en"><p>Olga S. Pershenkova, Assistant Lecturer at the Department of General and Clinical Pharmacology</p><p>Gomel </p></bio><email xlink:type="simple">70bssr@tut.by</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9716-4009</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михайлова Елена Ивановна, д.м.н., профессор, заведующий кафедрой общей и клинической  фармакологии</p><p>Гомель</p></bio><bio xml:lang="en"><p>Elena I. Mikhailova, Doctor of Medical Sciences, Professor at the Department of General and Clinical Pharmacology</p><p>Gomel</p></bio><email xlink:type="simple">elena.mikhailova@tut.by</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>07</month><year>2023</year></pub-date><volume>20</volume><issue>2</issue><fpage>7</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Першенкова О.С., Михайлова Е.И., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Першенкова О.С., Михайлова Е.И.</copyright-holder><copyright-holder xml:lang="en">Pershenkova O.S., Mikhailova E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2543">https://journal.gsmu.by/jour/article/view/2543</self-uri><abstract><p>Алкоголь является токсическим веществом, которое связано со спектром повреждений печени, включая простой стеатоз или жировую дистрофию печени, алкогольный гепатит, фиброз и цирроз. Алкогольная болезнь печени (АБП) — общий термин, используемый для обозначения этого спектра связанных с алкоголем повреждений печени. Чрезмерное или вредное употребление алкоголя входит в пятерку основных факторов риска смерти и инвалидности во всем мире и приводит к 2,5 млн смертей и 69,4 млн ежегодных лет жизни с поправкой на инвалидность. Диагноз АБП, как правило, может быть поставлен на основании анамнеза, клинических и лабораторных данных. Однако диагностика АБП может быть клинически сложной, поскольку не существует единого диагностического теста, подтверждающего этот диагноз, а пациенты могут не сообщать о степени употребления алкоголя.</p></abstract><trans-abstract xml:lang="en"><p>Alcohol is a toxic substance that is associated with a spectrum of liver damage, including simple steatosis or fatty- degeneration of liver, alcoholic hepatitis, fibrosis, and cirrhosis. Alcoholic liver disease (ALD) is the general term used for this spectrum of alcohol-related liver damage. Excessive or harmful alcohol use is among the top five risk factors for death and disability worldwide, causing 2.5 million deaths and 69.4 million annual disability-adjusted life years. The diagnosis of ABP can usually be made on the basis of anamnesis, clinical and laboratory findings. However, the diagnosis of ABP can be clinically challenging because there is no a single diagnostic test to confirm the diagnosis, and patients may not report the extent of their alcohol use.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>алкогольная болезнь печени</kwd><kwd>скрининг на алкоголь</kwd></kwd-group><kwd-group xml:lang="en"><kwd>alcoholic liver disease</kwd><kwd>alcohol screening</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH. ACG Clinical Guideline: Alcoholic Liver Disease. Am J Gastroenterol. 2018 Feb;113(2):175-194. 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