<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2022-19-2-16</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2287</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Разрыв матки во втором триместре во время медикаментозного прерывания беременности с использованием мизопростола</article-title><trans-title-group xml:lang="en"><trans-title>Uterine rupture in the second trimester during medical termination of pregnancy using misoprostol</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8904-279X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маевская</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mayeuskaya</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Mаевская Марина Васильевна, ассистeнт кафедры акушерства и гинекологии с курсом ФПКиП</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Maryna V. Mayeuskaya, Assistant Lecturer at the Department of Obstetrics and Gynecology with the course of the Faculty of Advanced Training and Rretraining</p><p>Gomel</p></bio><email xlink:type="simple">drmarina283@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>01</day><month>07</month><year>2022</year></pub-date><volume>19</volume><issue>2</issue><fpage>129</fpage><lpage>133</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Маевская М.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Маевская М.В.</copyright-holder><copyright-holder xml:lang="en">Mayeuskaya M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2287">https://journal.gsmu.by/jour/article/view/2287</self-uri><abstract><p>В статье описан случай разрыва матки во втором триместре беременности во время медикаментозного прерывания беременности с использованием мизопростола. Данный случай представляет несомненный интерес, так как разрыв матки во втором триместре беременности — крайне редкое явление, описанное в отечественной литературе. Изложенный материал может напомнить практикующим врачам о возможности такого осложнения.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a case of uterine rupture in the second trimester of pregnancy during medical termination of pregnancy using misoprostol. This case is of undoubted interest, since the rupture of the uterus in the second trimester of pregnancy is an extremely rare phenomenon described in domestic literature. The presented material may remind practicing doctors that this complication is likely to occur.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>разрыв матки</kwd><kwd>мизопростол</kwd><kwd>медикаментозный аборт</kwd></kwd-group><kwd-group xml:lang="en"><kwd>uterine rupture</kwd><kwd>misoprostol</kwd><kwd>medical abortion</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Савельев ГМ, Серов ВН, Сухих ГТ, ред. Клинические рекомендации. Акушерство и гинекология. 4-е издание. Моcква: ГЭОТАР-Медиа, 2019.</mixed-citation><mixed-citation xml:lang="en">Savelyev GM, Serov VN, Sukhoi GT, edit. Clinical recommendations. Obstetrics and gynecology. 4th edition. Moscow: GEOTAR-Media, 2019.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Salem Alsuwaidan, Amsha Saud Aburasyin, Wesam Abdulwasea Saeed Almekhla. Estimated Cost Analysis for Uterine Rupture. Women’s Health and Complications. 2020;2(1):1-6.</mixed-citation><mixed-citation xml:lang="en">Salem Alsuwaidan, Amsha Saud Aburasyin, Wesam Abdulwasea Saeed Almekhla. Estimated Cost Analysis for Uterine Rupture. Women’s Health and Complications. 2020;2(1):1-6.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Савельева ГМ, Бреслав ИЮ. Разрыв неоперированной матки во время родов. Российский вестник акушера-гинеколога. 2016;16(2):4-10. DOI: https://doi.org/10.17116/rosakush20161624-10</mixed-citation><mixed-citation xml:lang="en">Savelyeva GM, Breslav IYu. Rupture of an unoperated uterus during childbirth. Russian Bulletin of the obstetriciangynecologist. 2016;16(2):4-10. DOI: https://doi.org/10.17116/rosakush20161624-10</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Персианинов ЛС. Разрывы матки. Москва, 1952.</mixed-citation><mixed-citation xml:lang="en">Persianinov LS. Ruptures of the uterus. Moscow; 1952.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Drey EA, Foster DG, Jackson RA, Lee SJ, Cardenas LH, Darney PD. Risk factors associated with presenting for abortion in the second trimester. Obstet Gynecol. 2006 Jan;107(1):128-35. DOI: https://doi.org/10.1097/01.AOG.0000189095.32382.d0</mixed-citation><mixed-citation xml:lang="en">Drey EA, Foster DG, Jackson RA, Lee SJ, Cardenas LH, Darney PD. Risk factors associated with presenting for abortion in the second trimester. Obstet Gynecol. 2006 Jan;107(1):128-35. DOI: https://doi.org/10.1097/01.AOG.0000189095.32382.d0</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY. Williams Obstetrics. 23rd ed. McGraw-Hill Professional, 2009.</mixed-citation><mixed-citation xml:lang="en">Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Rouse DJ, Spong CY. Williams Obstetrics. 23rd ed. McGraw-Hill Professional, 2009.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Morris JL, Winikoff B, Dabash R, Weeks A, Faundes A, et al. FIGO’s updated recommendations for misoprostol used alone in gynecology and obstetrics. Int J Gynaecol Obstet. 2017 Sep;138(3):363-366. DOI: https://doi.org/10.1002/ijgo.12181</mixed-citation><mixed-citation xml:lang="en">Morris JL, Winikoff B, Dabash R, Weeks A, Faundes A, et al. FIGO’s updated recommendations for misoprostol used alone in gynecology and obstetrics. Int J Gynaecol Obstet. 2017 Sep;138(3):363-366. DOI: https://doi.org/10.1002/ijgo.12181</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Радзинский, ВЕ. Неразвивающаяся беременность в анамнезе: реабилитация и подготовка к следующей гестации. Методические рекомендации Междисциплинарной ассоциации специалистов репродуктивной медицины (МАРС). М.; 2021.</mixed-citation><mixed-citation xml:lang="en">Radzinsky VE, edit. Anamnesis of an undeveloped pregnancy: rehabilitation and preparation for the next gestation. Methodological recommendations of the Interdisciplinary Association of Specialists in Reproductive Medicine (MARS). M.; 2021.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Берер М. Обеспечение безопасности абортов: вопрос разумной политики и практики общественного здравоохранения. Проблемы репродуктивного здоровья. 2008;( Декабрь.):5-21. [дата обращения 2022 январь 17]. Режим доступа: http://www.reprohealth.info/files/rhmmoscow2-2008web.pdf</mixed-citation><mixed-citation xml:lang="en">Berger M. Ensuring the safety of abortions: the issue of reasonable public health policy and practice. Reproductive health problems. 2008 (December): 5-21. [date of access 2022 January 17]. Available from: http://www.reprohealth.info/files/rhmmoscow2-2008web.pdf</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Прилепская ВН, ред. Клиническая гинекология. Москва: МЕДпресс- информ; 2005.</mixed-citation><mixed-citation xml:lang="en">Prilepskaya VN, edit. Clinical gynecology. Moscow: MEDpress-inform; 2005.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">RCOG. The Care of Woman Requesting Induced Abortion: Evidence-based clinical guideline number 7. London: RCOG Press, 2004. Archived from the original. [date of access 2022 January 17]. Available from: https://www.rcog.org.uk/globalassets/documents/guidelines/abortion-guideline_web_1.pdf</mixed-citation><mixed-citation xml:lang="en">RCOG. The Care of Woman Requesting Induced Abortion: Evidence-based clinical guideline number 7. London: RCOG Press, 2004. Archived from the original. [date of access 2022 January 17]. Available from: https://www.rcog.org.uk/globalassets/documents/guidelines/abortion-guideline_web_1.pdf</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Safe abortion: technical and policy guidance for health system. 2nd ed.-World Health Organization, Department of Reproductive Health and Research, 2012. [date of access 2022 January]. Available from: http://www.who.int</mixed-citation><mixed-citation xml:lang="en">Safe abortion: technical and policy guidance for health system. 2nd ed.-World Health Organization, Department of Reproductive Health and Research, 2012. [date of access 2022 January 17]. Available from: http://www.who.int</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Safe Abortion: Technical and Policy Guidance for Health System. Geneva: WHO, 2003.</mixed-citation><mixed-citation xml:lang="en">Safe Abortion: Technical and Policy Guidance for Health System. Geneva: WHO, 2003.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kulier R, Kapp N, Gülmezoglu AM, Hofmeyr GJ, Cheng L, Campana A. Medical methods for first trimester abortion. Cochrane Database Syst Rev. 2011 Nov 9;2011(11):CD002855. DOI: https://doi.org/10.1002/14651858.CD002855.pub4</mixed-citation><mixed-citation xml:lang="en">Kulier R, Kapp N, Gülmezoglu AM, Hofmeyr GJ, Cheng L, Campana A. Medical methods for first trimester abortion. Cochrane Database Syst Rev. 2011 Nov 9;2011(11):CD002855. DOI: https://doi.org/10.1002/14651858.CD002855.pub4</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">RCOG. Late Intrauterine Fetal Death and Stillbirth: Evidence-based: clinical guideline number 10. London: RCOG Press, 2010. [date of access 2022 January 17]. Available from: https://www.rcog.org.uk/globalassets/documents/guidelines/gtg_55.pdf</mixed-citation><mixed-citation xml:lang="en">RCOG. Late Intrauterine Fetal Death and Stillbirth: Evidence-based: clinical guideline number 10. London: RCOG Press, 2010. [date of access 2022 January 17]. Available from: https://www.rcog.org.uk/globalassets/documents/guidelines/gtg_55.pdf</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Мочалова МН, Кузьмина ЛА, Мироненко АЮ, Лиханов ИВ, Мудров ВА. Клнический случай полного «немого» разрыва дна матки в первом периоде родов. Журнал акушерства и женских болезней. 2020;69(2):83-88. DOI: https://doi.org/10.17816/JOWD69283-88</mixed-citation><mixed-citation xml:lang="en">Mochalova MN, Kuzmina LA, Mironenko AYu, Likhanov IV, Mudrov VA. Clinical case of complete «mute» rupture of the uterine fundus in the first period of labor. Journal of Obstetrics and women’s diseases. 2020;69(2):83-88. DOI: https://doi.org/10.17816/JOWD69283-88</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Esmans A, Gerris J, Corthout E, Verdonk P, Declercq S. Placenta percreta causing rupture of an unscarred uterus at the end of the first trimester of pregnancy: Case report. Hum Reprod. 2004;19:2401-2403. DOI: https://doi.org/10.1093/humrep/deh421</mixed-citation><mixed-citation xml:lang="en">Esmans A, Gerris J, Corthout E, Verdonk P, Declercq S. Placenta percreta causing rupture of an unscarred uterus at the end of the first trimester of pregnancy: Case report. Hum Reprod. 2004;19:2401-2403. DOI: https://doi.org/10.1093/humrep/deh421</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Bandarian M, Bandarian F. Spontaneous rupture of the uterus during the 1st trimester of pregnancy. J Obstet Gynaecol. 2014;35:199-200. DOI: https://doi.org/10.3109/01443615.2014.937334</mixed-citation><mixed-citation xml:lang="en">Bandarian M, Bandarian F. Spontaneous rupture of the uterus during the 1st trimester of pregnancy. J Obstet Gynaecol. 2014;35:199-200. DOI: https://doi.org/10.3109/01443615.2014.937334</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Biljan MM, Cushing K, McDicken IW, Garden AS. Spontaneous uterine rupture in the first trimester of pregnancy. J Obstet Gynaecol. 1996;16:174-175. DOI: https://doi.org/10.3390/ijerph17082976</mixed-citation><mixed-citation xml:lang="en">Biljan MM, Cushing K, McDicken IW, Garden AS. Spontaneous uterine rupture in the first trimester of pregnancy. J Obstet Gynaecol. 1996;16:174-175. DOI: https://doi.org/10.3390/ijerph17082976</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Hefny AF, Kunhivalappil FT, Nambiar R, Bashir MO. A rare case of first-trimester ruptured bicornuate uterus in a primigravida. Int J Surg Case Rep. 2015;14:98-100. DOI: https://doi.org/10.1016/j.ijscr.2015.07.019</mixed-citation><mixed-citation xml:lang="en">Hefny AF, Kunhivalappil FT, Nambiar R, Bashir MO. A rare case of first-trimester ruptured bicornuate uterus in a primigravida. Int J Surg Case Rep. 2015;14:98-100. DOI: https://doi.org/10.1016/j.ijscr.2015.07.019</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Mahajan N, Moretti ML, Lakhi NA. Spontaneous early first and second trimester uterine rupture following roboticassisted myomectomy. J Obstet Gynaecol. 2018;39:278-280. DOI: https://doi.org/10.1080/01443615.2018.1466112</mixed-citation><mixed-citation xml:lang="en">Mahajan N, Moretti ML, Lakhi NA. Spontaneous early first and second trimester uterine rupture following robotic-assisted myomectomy. J Obstet Gynaecol. 2018;39:278-280. DOI: https://doi.org/10.1080/01443615.2018.1466112</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
