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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2021-18-4-11</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2116</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Эпидемиологический анализ злокачественных новообразований гортани в Беларуси за 2000–2019 гг.</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiological analysis of the malignant tumors of the larynx in Belarus over 2000–2019</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6849-2951</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шляга</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Shlyaga</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шляга Ирина Дмитриевна, к.м.н., доцент, заведующий кафедрой оториноларингологии с курсом офтальмологии</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Irina D. Shlyaga, PhD (Med), Associate Professor, Head of the Department of Otorhinolaryngology with the course of Ophthalmology</p><p>Gomel </p></bio><email xlink:type="simple">Irina.Shljaga@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3759-141X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колядич</surname><given-names>Ж. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaliadzich</surname><given-names>Zh. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Колядич Жанна Викторовна, д.м.н., заведующая лабораторией онкопатологии головы и шеи с группой онкопатологии центральной нервной системы</p><p>г. Минск</p></bio><bio xml:lang="en"><p>Zhanna V. Kaliadzich, DMedSc, Head of the Laboratory of Head and Neck Oncopathology with the Central Nervous System Oncopathology Group</p><p>Minsk</p></bio><email xlink:type="simple">janept@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9256-2910</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванов Сергей Анатольевич, к.м.н, доцент, доцент кафедры онкологии</p><p>г. Гомель</p></bio><bio xml:lang="en"><p>Sergey A. Ivanov, PhD (Med), Associate Professor, Associate Professor at the Department of Oncology</p><p>Gomel</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6335-1404</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евмененко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yaumenenka</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евмененко Алеся Александровна, специалист по канцер-регистру</p><p>г. Минск</p></bio><bio xml:lang="en"><p>Alesia A. Yaumenenka, a cancer registry professional</p><p>Minsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Республиканский научно-практический центр онкологии и медицинской радиологии им. Н. Н. Александрова</institution></aff><aff xml:lang="en"><institution>N.N. Alexandrov National Cancer Centre of Belarus</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2021</year></pub-date><volume>18</volume><issue>4</issue><fpage>83</fpage><lpage>92</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шляга И.Д., Колядич Ж.В., Иванов С.А., Евмененко А.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Шляга И.Д., Колядич Ж.В., Иванов С.А., Евмененко А.А.</copyright-holder><copyright-holder xml:lang="en">Shlyaga I.D., Kaliadzich Z.V., Ivanov S.A., Yaumenenka A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2116">https://journal.gsmu.by/jour/article/view/2116</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Проанализировать основные медико-статистические показатели заболеваемости злокачественными новообразованиями гортани в Республике Беларусь.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Материалом для исследования послужили данные Белорусского канцер-регистра о всех выявленных случаях заболеваний злокачественными новообразованиями гортани в Республике Беларусь за 2000–2019 гг. Исследованы следующие показатели: стандартизованная заболеваемость, грубая интенсивная заболеваемость, смертность отдельно для всего населения и населения трудоспособного возраста, для городского и сельского населения, мужчин и женщин. Выполнено сравнение эпидемиологических показателей в период 2000–2005 гг. и 2015–2019 гг. в стране в целом и в областях Республики Беларусь.</p></sec><sec><title>Результаты</title><p>Результаты. Показатель стандартизованной заболеваемости в Беларуси увеличился с 4,2 случая на 100 тыс. населения в 2000 г. до 5,8 — в 2019 г. Грубый интенсивный показатель заболеваемости увеличился, соответственно, с 5,5 до 7,3. Отмечено увеличение заболеваемости трудоспособного населения с 4,0 в 2000 г. до 4,3 в — 2019 г. Грубые интенсивные показатели заболеваемости мужчин в среднем в 33,9 раза выше, чем женщин, а у городских жителей — в 1,7 раза ниже, чем у сельских. Максимальный прирост заболеваемости зарегистрирован у жителей сельской местности трудоспособного возраста — на 60,3 % за период мониторинга. Статистически значимое большее увеличение заболеваемости было отмечено в г. Минске. Показатели заболеваемости статистически значимо ниже республиканского уровня зарегистрированы в г. Минске. В остальных регионах отличие уровня заболеваемости и динамики роста не имели значимого различия с показателями в Беларуси в целом.</p></sec><sec><title>Заключение</title><p>Заключение. Злокачественные новообразования гортани характеризуются медленным ростом заболеваемости в Беларуси в течение последних 20 лет. Наблюдаемые эпидемиологические тенденции определяют актуальность проблемы профилактики и своевременной диагностики злокачественных новообразований данной локализации.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. To analyze basic medico-statistical indices of the morbidity rates of the malignant tumors of the larynx in the Republic of Belarus.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. Data of the Belarusian Cancer Register on all detected cases of the malignant tumors of the larynx in the Republic of Belarus over 2000-2019 served as the material of the study. The following rates were studied: age standardized morbidity, gross intensive morbidity, morbidity separately in the general population and working age population, in urban and rural population, males and females. All epidemiological indices for the periods 2000-2005 and 2015-2019 in the country and across the regions of the Republic of Belarus were compared.</p></sec><sec><title>Results</title><p>Results. The age standardized morbidity rate in Belarus increased from 4.2 cases/year per 100,000 population in 2000 to 5.8 in 2019. The gross intensive morbidity rate increased from 5.5 to 7.3, respectively. An increase in the morbidity rate from 4.0 in 2000 to 4.3 in 2019 was noted in the working age population. The gross intensive morbidity rates in males were on average 33.9 times higher than in females, and in the urban population – 1.7 times lower than those in the rural population. The maximal increase in the morbidity rate was registered in the working age population of rural areas – by 60.3% during the monitored period. A statistically significant increase in the morbidity rate was noted in the city of Minsk. The morbidity rates registered in Minsk were statistically significantly lower than those in the republic. In other regions, there was no significant difference in the morbidity rates and growth dynamics from the indices in Belarus as a whole.</p></sec><sec><title>Conclusion</title><p>Conclusion. Malignant tumors of the larynx are characterized by a slow increase of the morbidity rate for the last 20 years in Belarus. The observed epidemiological trends deter</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>злокачественные новообразования гортани</kwd><kwd>гортань</kwd><kwd>эпидемиология</kwd><kwd>заболеваемость</kwd></kwd-group><kwd-group xml:lang="en"><kwd>malignant tumors of the larynx</kwd><kwd>larynx</kwd><kwd>epidemiology</kwd><kwd>morbidity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cancer today. 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