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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2021-18-3-9</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2035</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Факторы риска внутриутробной инфекции новорожденного у беременных с урогенитальной инфекцией</article-title><trans-title-group xml:lang="en"><trans-title>Risk factors for neonatal intrauterine infection in pregnant women with urogenital infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0718-8881</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захаренкова</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharenkova</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захаренкова Татьяна Николаевна, к.м.н., доцент, заведующий кафедрой акушерства и гинекологии с курсом ФПКиП </p><p>Гомель</p></bio><bio xml:lang="en"><p>Tatiana N. Zakharenkova, PhD (Med), Associate Professor, Head of the Department of Obstetrics and Gynecology with the course of the Faculty of Professional Development and Retraining </p><p>Gomel</p></bio><email xlink:type="simple">tera03@yandex.by</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9971-0464</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лашкевич</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lashkevich</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лашкевич Елена Леонидовна, к.м.н., ассистент кафедры акушерства и гинекологии с курсом ФПКиП </p><p>Гомель</p></bio><bio xml:lang="en"><p>Elena L. Lashkevich, PhD (Med), Assistant Lecturer at the Department of Obstetrics and Gynecology with the course of the Faculty of Professional Development and Retraining </p><p>Gomel</p></bio><email xlink:type="simple">Lashkevichelena@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5451-9519</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лакудас</surname><given-names>E. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lakudas</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лакудас Елена Львовна, к.м.н., ассистент кафедры акушерства и гинекологии с курсом ФПКиП</p><p>Гомель</p></bio><bio xml:lang="en"><p>Elena L. Lakudas, PhD (Med), Assistant Lecturer at the Department of Obstetrics and Gynecology with the course of the Faculty of Professional Development and Retraining </p><p>Gomel</p></bio><email xlink:type="simple">Lakudene@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2021</year></pub-date><volume>18</volume><issue>3</issue><fpage>72</fpage><lpage>79</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Захаренкова Т.Н., Лашкевич Е.Л., Лакудас E.Л., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Захаренкова Т.Н., Лашкевич Е.Л., Лакудас E.Л.</copyright-holder><copyright-holder xml:lang="en">Zakharenkova T.N., Lashkevich E.L., Lakudas E.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2035">https://journal.gsmu.by/jour/article/view/2035</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Определить клинико-анамнестические факторы риска внутриутробной инфекции (ВУИ) новорожденного у беременных с урогенитальной инфекцией (УГИ).</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Обследована 431 пациентка: основная группа (группа 1) — 353 женщины с УГИ во время беременности (подгруппа 1А — 215 женщин, у детей которых диагностирована ВУИ, подгруппа 1Б — 138 женщин, дети которых были рождены без признаков ВУИ); группа сравнения (группа 2) — 78 женщин без УГИ во время беременности (подгруппа 2А — 44 пациентки, дети которых родились с признаками ВУИ, подгруппа 2Б — 34 женщины, у детей которых не было ВУИ). Изучали акушерско-гинекологический и соматический анамнез пациентов, течение беременности.</p></sec><sec><title>Результаты</title><p>Результаты. Наличие в анамнезе у беременных с УГИ гинекологических и соматических заболеваний было ассоциировано со значимым увеличением риска реализации ВУИ новорожденного (р = 0,003 и р = 0,005 соответственно). Значимо чаще у беременных с УГИ в анамнезе наблюдались вагиниты (р = 0,041) и фоновые и предраковые заболевания шейки матки (p = 0,027). Беременность на фоне УГИ протекала с рецидивирующей угрозой прерывания (p = 0,046), чаще осложнялась острой респираторной инфекцией (p ˂ 0,001) и значимо чаще заканчивалась преждевременными родами — 24,7 % (р = 0,009).</p></sec><sec><title>Заключение</title><p>Заключение. Поиск объективных критериев развития ВУИ плода является важной и сложной задачей современного акушерства. Анализ анамнеза беременных с урогенитальной инфекцией, а также своевременная диагностика и адекватное лечение урогенитальной инфекции и острой респираторной инфекции позволят снизить недонашивание беременности и частоту ВУИ новорожденного</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. To determine the clinical and anamnestic risk factors for neonatal intrauterine infection (IUI) in pregnant women with urogenital infections (UGI).</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 431 patients were examined: the main group (group 1) — 353 women with UGI during pregnancy (subgroup 1A — 215 women whose children were diagnosed with IUI, subgroup 1B — 138 women whose children were born without signs of IUI; the comparison group (group 2) — 78 women without UGI during pregnancy (subgroup 2A — 44 patients whose children were born with signs of IUI, subgroup 2B — 34 women whose children did not have IUI. We studied the obstetric and gynecological, somatic anamnesis of the patients, the course of their pregnancy.</p></sec><sec><title>Results</title><p>Results. The presence of gynecological and somatic diseases in the anamnesis of the pregnant women with UGI was associated with a signifcant increase of the risk for neonatal IUI (p = 0.003 and p = 0.005, respectively). Vaginitis (p = 0.041), background and precancerous diseases of the cervix (p = 0.027) were signifcantly most prevalent in the pregnant women with UGIs in their history. Pregnancy complicated by UGI proceeded with a recurrent miscarriage risk (p = 0.046) was most often accompanied by acute respiratory infection (p ˂ 0.001) and signifcantly most often ended in premature birth — 24.7% (p = 0.009).</p></sec><sec><title>Conclusion</title><p>Conclusion. The search for objective criteria for the development of neonatal IUI is an important and complex task of modern obstetrics. The analysis of the anamnesis of pregnant women with urogenital infections, as well as timely diagnosis and adequate treatment of urogenital infection and acute respiratory infection will reduce the miscarriage rate and the incidence rate of neonatal IUI.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>урогенитальная инфекция</kwd><kwd>внутриутробная инфекция</kwd><kwd>гинекологический и соматический анамнез</kwd><kwd>осложнения беременности</kwd></kwd-group><kwd-group xml:lang="en"><kwd>urogenital infection</kwd><kwd>intrauterine infection</kwd><kwd>gynecological and somatic anamnesis</kwd><kwd>pregnancy complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bennett PR, Brown RG, MacIntyre DA. Vaginal Microbiome in Preterm Rupture of Membranes. Obstet Gynecol Clin North Am. 2020 Dec;47(4):503-521. 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