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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2021-18-3-7</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-2033</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Окклюзия вены, прилежащей к метастазу колоректального рака в печени, как способ повышения радикальности чрескожной радиочастотной термоаблации</article-title><trans-title-group xml:lang="en"><trans-title>Occlusion of the vein adjacent to colorectal cancer liver metastasis as a way to increase the radicality of percutaneous radiofrequency thermal ablation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3997-7612</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурашко</surname><given-names>К. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Murashko</surname><given-names>K. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мурашко Константин Леонидович, врач УЗИ отделения ультразвуковой диагностики </p><p>Гомель</p></bio><bio xml:lang="en"><p>Konstantin L. Murashko, ultrasound diagnostician at the Department of Ultrasound Diagnostics </p><p>Gomel</p></bio><email xlink:type="simple">kostya199172@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0808-183X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юрковский</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Yurkovskiy</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юрковский Алексей Михайлович, к.м.н., доцент, заведующий кафедры лучевой диагностики и лучевой терапии </p><p>Гомель</p></bio><bio xml:lang="en"><p>Aliaxei М. Yurkovskiy, PhD (Med), Associate Professor, Head of the Department of Radiation Diagnostics and Radiation Therapy </p><p>Gomel</p></bio><email xlink:type="simple">yurkovsky@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский областной клинический онкологический диспансер</institution></aff><aff xml:lang="en"><institution>Gomel Regional Clinical Oncological Dispensary</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2021</year></pub-date><volume>18</volume><issue>3</issue><fpage>57</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мурашко К.Л., Юрковский А.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Мурашко К.Л., Юрковский А.М.</copyright-holder><copyright-holder xml:lang="en">Murashko K.L., Yurkovskiy A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/2033">https://journal.gsmu.by/jour/article/view/2033</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Оценить эффективность предварительной коагуляции вены, прилежащей к опухолевому узлу, при сонографически контролируемой чрескожной радиочастотной термоаблации периваскулярных метастазов колоректального рака в печени.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Для решения поставленной задачи проведено сопоставление результатов сонографически контролируемой чрескожной радиочастотной термоаблации периваскулярных метастазов колоректального рака в печени 27 пациентов (возраст — 60,5 (58; 68) года) без предварительной коагуляции прилежащей вены (группа контроля) и 26 пациентов (62,0 (60; 74])) с предварительной коагуляцией прилежащей вены (опытная группа).</p></sec><sec><title>Результаты</title><p>Результаты. Выявлена меньшая инцидентность остаточной опухоли в зоне аблации у пациентов с предварительной коагуляцией прилежащей вены (14,3 % против 29,0 % у пациентов группы контроля) и большая безрецидивная выживаемость пациентов (65,2 % против 53,6 % и 55,6 % против 33,3 %) в сравнении с группой без предварительной коагуляции прилежащей вены (через 6 и 12 месяцев соответственно).</p></sec><sec><title>Заключение</title><p>Заключение. Предварительная коагуляция вены, прилежащей к метастазу колоректального рака в печени, позволяет уменьшить эффект теплоотведения из зоны РЧА, тем самым обеспечивая большую радикальность воздействия и, соответственно, меньшую инцидентность остаточной опухоли в зоне аблации, а также большую безрецидивную выживаемость пациентов, причем без существенных сопутствующих изменений печени (атрофии сегмента) в зоне воздействия.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. To evaluate the effectiveness of preoperative coagulation of the vein adjacent to a tumor nodule in sonographically-guided percutaneous radiofrequency thermal ablation of perivascular liver metastases of colorectal cancer.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. To address the issue, we compared the results of sonographically-guided percutaneous radiofrequency thermal ablation of perivascular liver metastases of colorectal cancer in 27 patients (aged 60.5 (58; 68) years) without prior coagulation of the adjacent vein (control group) and 26 patients (62.0 (60; 74)) with prior coagulation of the adjacent vein (experimental group).</p></sec><sec><title>Results</title><p>Results. Lower incidence of residual tumor in the ablation area in the patients with prior coagulation of the adjacent vein (14.3 % vs. 29 % of the patients in the control group) and a higher relapse-free survival of such patients (65.2 % vs. 53.6 % and 55.6 % vs. 33.3 %) were reported as compared to the group without prior coagulation of the adjacent vein (after 6 and 12 months, respectively).</p></sec><sec><title>Conclusion</title><p>Conclusion. Preoperative coagulation of the vein adjacent to colorectal cancer liver metastasis allows reducing the effect of heat removal from the RFA zone, thereby contributing to higher radicality of the treatment and resulting both in a lower incidence of residual tumor in the ablation zone and a higher relapse-free survivalof patients, notably without signifcant concomitant changes in the affected part of the liver (segment atrophy).</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>радиочастотная термоаблация</kwd><kwd>метастазы печени</kwd><kwd>коагуляция</kwd><kwd>локальное тепловое воздействие</kwd><kwd>ультразвуковое исследование</kwd><kwd>компьютерная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>radiofrequency thermoablation</kwd><kwd>liver metastases</kwd><kwd>coagulation</kwd><kwd>local thermal exposure</kwd><kwd>ultrasound</kwd><kwd>computed tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kopetz S, Chang GJ, Overman MJ, Eng C, Sargent D. 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