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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2021-18-2-20</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1953</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ КЛИНИЧЕСКОЙ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Цитолитический синдром на фоне лечения COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Cytolytic syndrome associated with the treatment for COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5298-8343</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данилов</surname><given-names>Д. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Danilau</surname><given-names>D. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитрий Евгеньевич Данилов, д.м.н., доцент, профессор кафедры инфекционных болезней</p><p>Минск</p></bio><bio xml:lang="en"><p>Dzmitry E. Danilau, DMedSc, Associate Professor, Professor at the Department of Infectious Diseases</p><p>Minsk</p></bio><email xlink:type="simple">infections@bsmu.by</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Белорусский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Belarusian State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2021</year></pub-date><volume>18</volume><issue>2</issue><fpage>140</fpage><lpage>146</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Данилов Д.Е., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Данилов Д.Е.</copyright-holder><copyright-holder xml:lang="en">Danilau D.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1953">https://journal.gsmu.by/jour/article/view/1953</self-uri><abstract><p>В статье приведено описание клинического случая повышения уровня печеночных трансаминаз в отсроченном периоде лечения у пациента с коронавирусной инфекцией COVID-19 с использованием ремдесивира. Описано возможное влияние стеатоза печени на выраженность цитолитического синдрома у пациентов на фоне течения COVID-19.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a clinical case of an increased level of hepatic transaminases during a delayed period of the treatment in a patient with coronavirus disease COVID-19 using remdesivir and a possible effect of hepatic steatosis on the severity of cytolytic syndrome associated with the course of COVID-19.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>повышение трансаминаз</kwd><kwd>цитолитический синдром</kwd><kwd>ремдесивир</kwd><kwd>стеатоз печени</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>increased transaminases</kwd><kwd>cytolytic syndrome</kwd><kwd>remdesivir</kwd><kwd>hepatic steatosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Coronavirus COVID-19 (2019-nCoV) [Electronic resource]. 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