zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2021-18-2-6zdor-1938Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEСкрининговая диагностика синдрома апноэ сна у пациентов с инфарктом головного мозгаScreening diagnosis of sleep apnea syndrome in patients with ischemic strokehttps://orcid.org/0000-0002-5210-7593СереброваЕ. В.SerebrovaE. V.

Сереброва Екатерина Вячеславовна, старший преподаватель кафедры неврологии и нейрохирургии с курсами медицинской реабилитации, психиатрии, ФПКиП

Гомель

Ekaterina V. Serebrova, Senior Lecturer at the Department of Neurology and Neurosurgery with the courses of Medical Rehabilitation, Psychiatry, Faculty of Professional Development and Retraining

Gomel

serebrovaev@mail.ruГомельский государственный медицинский университетGomel State Medical University2021290620211824047Copyright © Сереброва Е.В., 20212021Сереброва Е.В.Serebrova E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/1938Цель исследования

Цель исследования: оценить эффективность опросника STOP-BANG, Берлинского опросника, шкалы сонливости Эпворта в скрининговой диагностике синдрома апноэ сна у пациентов с инфарктом головного мозга.

Материалы и методы

Материалы и методы. Обследовано 107 пациентов (45 женщин и 62 мужчины; медиана возраста — 64 (56; 74) (от 36 до 88 лет). Исследование включало анкетирование с использованием опросника STOP-BANG, Берлинского опросника, шкалы сонливости Эпворта и ночную респираторную полиграфию.

Результаты

Результаты. Среди 75 пациентов с синдромом апноэ сна опросник STOP-BANG, Берлинский опросник и шкала сонливости Эпворта показали чувствительность — 91, 72, 51 % соответственно, специфичность — 53, 78, 84 % соответственно, диагностическую точность — 72, 75, 68 % соответственно, прогностическую ценность положительного результата — 82, 89, 88 % соответственно и прогностическую ценность отрицательного результата — 71, 54, 42 % соответственно.

Заключение

Заключение. Опросник STOP-BANG и Берлинский опросник являются удобными и информативными для скрининговой оценки риска синдрома апноэ сна у пациентов с инфарктом головного мозга, но их применение должно дополняться инструментальными методами диагностики для достоверного исключения нарушений дыхания во сне.

Objective

Objective: to evaluate the effectiveness of the STOP-BANG questionnaire, Berlin questionnaire, and the Epworth sleepiness scale in the screening diagnosis of sleep apnea syndrome in patients with ischemic stroke.

Materials and methods

Materials and methods. We examined 107 patients (45 women and 62 men; the median age was 64 (56; 74) (aged 36–88). The study involved questioning using the STOP-BANG questionnaire, Berlin questionnaire, Epworth sleepiness scale, and nocturnal respiratory polygraphy.

Results

Results. Among 75 patients with sleep apnea syndrome, the STOP-BANG questionnaire, Berlin questionnaire, and the Epworth sleepiness scale showed sensitivity — 91 %, 72 %, 51 %, respectively, specificity — 53 %, 78 %, 84 %, respectively, diagnostic accuracy — 72 %, 75 %, 68 % respectively, positive predictive value — 82 %, 89 %, 88 %, respectively, and negative predictive value — 71 %, 54 %, 42 %, respectively.

Conclusion

Conclusion. The STOP-BANG questionnaire and the Berlin questionnaire are convenient and informative for the screening assessment of the risk of sleep apnea syndrome in patients with ischemic stroke, but their use should be complemented by instrumental diagnostic methods for reliable exclusion of sleep-disordered breathing.

синдром апноэ снаинсультопросникиsleep apnea syndromestrokequestionnairesReferencesБузунов РВ, Пальман АД, Мельников АЮ, Авербух ВМ, Мадаева ИМ, Куликов АН. Диагностика и лечение синдрома обструктивного апноэ сна у взрослых. Рекомендации Российского общества сомнологов. Эффективная фармакотерапия. 2018;(35):34–43.Buzunov RV, Palman AD, Melnikov AYu, Averbukh VM, Madaeva IM, Kulikov AN. Diagnosis and treatment of obstructive sleep apnea syndrome in adults. Recommendations of the Russian Society of Somnologists. Effective Pharmacotherapy. 2018;(35):34–43. (in Russ.)Floras JS. Sleep Apnea and Cardiovascular Disease: An Enigmatic Risk Factor. Circ Res. 2018 Jun 8;122(12):1741–764. https://doi.org/10.1161/CIRCRESAHA.118.310783Floras JS. Sleep Apnea and Cardiovascular Disease: An Enigmatic Risk Factor. Circ Res. 2018 Jun 8;122(12):1741–1764. https://doi.org/10.1161/CIRCRESAHA.118.310783Nair R, Radhakrishnan K, Chatterjee A, Gorthi SP, Prabhu VA. Sleep Apnea-Predictor of Functional Outcome in Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2019 Mar;28(3):807–814. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.11.030Nair R, Radhakrishnan K, Chatterjee A, Gorthi SP, Prabhu VA. Sleep Apnea-Predictor of Functional Outcome in Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2019 Mar;28(3):807–814. https://doi.org/10.1016/j.jstrokecere brovasdis.2018.11.030Salman LA, Shulman R, Cohen JB. Obstructive Sleep Apnea, Hypertension, and Cardiovascular Risk: Epidemiology, Pathophysiology, and Management. Curr Cardiol Rep. 2020 Jan 18;22(2):6. https://doi.org/10.1007/s11886-020-1257-ySalman LA, Shulman R, Cohen JB. Obstructive Sleep Apnea, Hypertension, and Cardiovascular Risk: Epidemiology, Pathophysiology, and Management. Curr Cardiol Rep. 2020 Jan 18;22(2):6. https://doi.org/10.1007/s11886-020-1257-yAmra B, Javani M, Soltaninejad F, Penzel T, Fietze I, Schoebel C, Farajzadegan Z. Comparison of Berlin Questionnaire, STOP-Bang, and Epworth Sleepiness Scale for Diagnosing Obstructive Sleep Apnea in Persian Patients. Int J Prev Med. 2018 Mar 9;9:28. https://doi.org/10.4103/ijpvm.IJPVM_131_17Amra B, Javani M, Soltaninejad F, Penzel T, Fietze I, Schoebel C, Farajzadegan Z. Comparison of Berlin Questionnaire, STOP-Bang, and Epworth Sleepiness Scale for Diagnosing Obstructive Sleep Apnea in Persian Patients. Int J Prev Med. 2018 Mar 9;9:28. https://doi.org/10.4103/ijpvm.IJPVM_131_17El-Sayed IH. Comparison of four sleep questionnaires for screening obstructive sleep apnea. Egyptian Journal of Chest Diseases and Tuberculosis. 2012;61(4):433–441.El-Sayed IH. Comparison of four sleep questionnaires for screening obstructive sleep apnea. Egyptian Journal of Chest Diseases and Tuberculosis. 2012;61(4):433–441.Nagappa M, Liao P, Wong J, Auckley D, Ramachandran SK, Memtsoudis S, et al. Validation of the STOP-Bang Questionnaire as a Screening Tool for Obstructive Sleep Apnea among Different Populations: A Systematic Review and Meta-Analysis. PLoS ONE. 2015;10(12):e0143697. https://doi.org/10.1371/journal.pone.0143697Nagappa M, Liao P, Wong J, Auckley D, Ramachandran SK, Memtsoudis S, et al. Validation of the STOP-Bang Questionnaire as a Screening Tool for Obstructive Sleep Apnea among Different Populations: A Systematic Review and Meta-Analysis. PLoS ONE. 2015;10(12):e0143697. https://doi.org/10.1371/journal.pone.0143697Chiu HY, Chen PY, Chuang LP, Chen NH, Tu YK, Hsieh YJ, Wang YC, Guilleminault C. Diagnostic accuracy of the Berlin questionnaire, STOP-BANG, STOP, and Epworth sleepiness scale in detecting obstructive sleep apnea: A bivariate meta-analysis. Sleep Med Rev. 2017;36:57–70.Chiu HY, Chen PY, Chuang LP, Chen NH, Tu YK, Hsieh YJ, Wang YC, Guilleminault C. Diagnostic accuracy of the Berlin questionnaire, STOP-BANG, STOP, and Epworth sleepiness scale in detecting obstructive sleep apnea: A bivariate meta-analysis. Sleep Med Rev. 2017;36:57–70.Amra B, Rahmati B, Soltaninejad F, Feizi A. Screening Questionnaires for Obstructive Sleep Apnea: An Updated Systematic Review. Oman Medical Journal. 2018;3(33):184–192.Amra B, Rahmati B, Soltaninejad F, Feizi A. Screening Questionnaires for Obstructive Sleep Apnea: An Updated Systematic Review. Oman Medical Journal. 2018;3(33):184–192.Pereira EJ, Driver HS, Stewart SC, Fitzpatrick MF. Comparing a combination of validated questionnaires and level III portable monitor with polysomnography to diagnose and exclude sleep apnea. J Clin Sleep Med. 2013;9(12):1259–1266.Pereira EJ, Driver HS, Stewart SC, Fitzpatrick MF. Comparing a combination of validated questionnaires and level III portable monitor with polysomnography to diagnose and exclude sleep apnea. J Clin Sleep Med. 2013;9(12):1259–1266.Saldías Peñafiel F, Gassmann Poniachik J, Canelo López A, Uribe Monasterio J, Díaz Patiño O. Accuracy of sleep questionnaires for obstructive sleep apnea syndrome screening. Rev Med Chile. 2018;146:1123–1134.Saldías Peñafiel F, Gassmann Poniachik J, Canelo López A, Uribe Monasterio J, Díaz Patiño O. Accuracy of sleep questionnaires for obstructive sleep apnea syndrome screening. Rev Med Chile. 2018;146:1123–1134.Kim B, Lee EM, Chung YS, Kim WS, Lee SA. The utility of three screening questionnaires for obstructive sleep apnea in a sleep clinic setting. Yonsei Med J. 2015;56(3):684–690.Kim B, Lee EM, Chung YS, Kim WS, Lee SA. The utility of three screening questionnaires for obstructive sleep apnea in a sleep clinic setting. Yonsei Med J. 2015;56(3):684–690.

The authors declare that there are no conflicts of interest present.