zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2021-18-2-4zdor-1936Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEПредоперационная механическая подготовка толстой кишки в хирургии колоректального ракаPreoperative mechanical large bowel preparation in colorectal cancer surgeryhttps://orcid.org/0000-0003-4682-2045ДятловА. П.DyatlovA. P.

Дятлов Александр Петрович, ассистент кафедры онкологии, УО «Гомельский государственный медицинский университет»; врач-онколог-хирург онкоабдоминального отделения УЗ «Гомельский областной клинический онкологический диспансер

Гомель

Alexandr P. Dyatlov, Assistant Lecturer at the Department of Oncology, Gomel State Medical University; surgical oncologist at the Abdominal Oncology Ward of Gomel Regional Clinical Oncology Center

Gomel

dyatlov-ap@mail.ruhttps://orcid.org/0000-0002-3796-0342МихайловИ. В.MikhailovI. V.

Михайлов Игорь Викторович, к.м.н., доцент, заведующий кафедрой онкологии

Гомель

Igor` V. Mikhailov, PhD (Med), Associate Professor, Head of the Department of Oncology

Gomel

igormikhailov-2014@yandex.ruhttps://orcid.org/0000-0002-1512-8539КудряшовВ. А.KudryashovV. A.

Кудряшов Вадим Андреевич, заведующий онкологическим абдоминальным отделением

Гомель

Vadim A. Kudryashov, Head of the Abdominal Oncology Ward

Gomel

vadimkudryashov@tut.byhttps://orcid.org/0000-0002-5826-0185ГнедькоК. А.Gned`koK. A.

Гнедько Ксения Александровна, студентка 6 курса

Гомель

Kseniya A. Gned`ko, six-year student

Gomel

Гомельский государственный медицинский университет; Гомельский областной клинический онкологический диспансерGomel State Medical University; Gomel Regional Clinical Oncology CenterГомельский государственный медицинский университетGomel State Medical UniversityГомельский областной клинический онкологический диспансерGomel Regional Clinical Oncology Center2021290620211822532Copyright © Дятлов А.П., Михайлов И.В., Кудряшов В.А., Гнедько К.А., 20212021Дятлов А.П., Михайлов И.В., Кудряшов В.А., Гнедько К.А.Dyatlov A.P., Mikhailov I.V., Kudryashov V.A., Gned`ko K.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/1936Цель исследования

Цель исследования: проанализировать данные литературных источников об эффективности предоперационной механической подготовки кишечника (МПК) и провести на основе собственных данных сравнительный анализ непосредственных результатов МПК у пациентов, оперированных по поводу рака правых отделов ободочной кишки.

Материалы и методы

Материалы и методы. Проведен обзор литературных источников, посвященных применению МПК и ретроспективный анализ непосредственных результатов оперативных вмешательств по поводу рака правых отделов ободочной кишки у 349 пациентов с применением препаратов полиэтиленгликоля (ПЭГ) в качестве МПК (n = 186) и без использования ПЭГ (n = 163).

Результаты

Результаты. Частота осложнений у пациентов I и II группы составила 6,7 и 9,8 % (p > 0,05), несостоятельность анастомоза — 0,6 и 1,6 % (p > 0,05), послеоперационная летальность — 1,2 и 1,6 % (p > 0,05), средняя продолжительность послеоперационного периода — 14,9 и 12,1 дня соответственно (p > 0,05).

Заключение

Заключение. Применение предоперационной МПК препаратами ПЭГ не приводит к улучшению непосредственных результатов хирургического лечения пациентов с раком правой половины ободочной кишки.

Objective

Objective: to analyze literature data on the effectiveness of preoperative mechanical bowel preparation (MBP), and on the basis of our own data to perform a comparative analysis of immediate MBP results in patients operated on right-sided colon cancer.

Materials and methods

Materials and methods. We reviewed literature data relevant to the use of MBP and performed a retrospective analysis of the immediate results of surgical interventions on right-sided colon cancer in 349 patients having undergone MBP with polyethylene glycol (PEG) compounds (n = 186) and without the use of PEG (n = 163).

Results

Results. The incidence rates of complications in the patients of groups I and II were 6.7 % and 9.8 % (P>0.05), anastomotic leak rates were 0.6 % and 1.6 % (P>0.05), postoperative death rates — 1.2 % and 1.6 % (P>0.05), the average durations of the postoperative period were 14.9 and 12.1 days, respectively (P>0.05).

Conclusion

Conclusion. The use of preoperative MBP with PEG compounds does not result in enhancing the immediate results of the surgical treatment of patients with right-sided cancer.

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The authors declare that there are no conflicts of interest present.