<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2017-14-4-9</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1835</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЕ ТЕХНОЛОГИИ ДИАГНОСТИКИ И ЛЕЧЕНИЯ ПРЕДОПУХОЛЕВЫХ СОСТОЯНИЙ И ПРОФИЛАКТИКИ РАКА ЖЕЛУДКА</article-title><trans-title-group xml:lang="en"><trans-title>MODERN TECHNIQUES OF DIAGNOSIS AND TREATMENT OF PRECANCEROUS CONDITIONS AND PREVENTIONOF GASTRIC CANCER</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Платошкин</surname><given-names>Э. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Platoshkin</surname><given-names>E. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воропаева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Voropayeva</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бредихина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bredikhina</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борсук</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Borsuk</surname><given-names>A. D.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Войтович</surname><given-names>В. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Voytovich</surname><given-names>V. D.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Республиканский научно-практический центр радиационной медицины и экологии человека</institution></aff><aff xml:lang="en"><institution>Republican Research Center for Radiation Medicine and Human Ecology</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2017</year></pub-date><volume>0</volume><issue>4</issue><fpage>45</fpage><lpage>49</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Платошкин Э.Н., Воропаева А.В., Бредихина Е.В., Борсук А.Д., Войтович В.Д., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Платошкин Э.Н., Воропаева А.В., Бредихина Е.В., Борсук А.Д., Войтович В.Д.</copyright-holder><copyright-holder xml:lang="en">Platoshkin E.N., Voropayeva A.V., Bredikhina E.V., Borsuk A.D., Voytovich V.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1835">https://journal.gsmu.by/jour/article/view/1835</self-uri><abstract><p>В статье приводятся данные международных согласительных документов по диагностике и лечению предраковых изменений и состояний слизистой оболочки желудка. Анализируется опыт применения современных диагностических технологий мультидисциплинарной командой специалистов, занимающихся профилактикой рака желудка. В заключении констатируется возможность перехода в вопросах канцеропревенции с позиций «доказательной медицины» на персонифицированные технологии диагностики и лечения.</p></abstract><trans-abstract xml:lang="en"><p>The article presents data of international consensuses on the diagnosis and treatment of precancerous changes and conditions of the gastric mucosa and analyzes the experience of application of modern diagnostic techniques by the multidisciplinary team of specialists engaged in the prevention of gastric cancer. In conclusion, the article states the possibility of transition from the position of «evidence-based medicine» to personalized techniques of diagnosis and treatment in the matters of cancer prevention.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Helicobacter pylori</kwd><kwd>диагностика</kwd><kwd>лечение</kwd><kwd>рак желудка</kwd><kwd>профилактика</kwd><kwd>Helicobacter pylori</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd><kwd>gastric cancer</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Genta, R.M. Gastric precancerous lesions /R. M. Genta, M. Rugge// Gut. - 1999. - Vol. 45. - P.15-18.</mixed-citation><mixed-citation xml:lang="en">Genta, R.M. Gastric precancerous lesions /R. M. Genta, M. Rugge// Gut. - 1999. - Vol. 45. - P.15-18.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Correa, P. A.Human model of gastric carcinogenesis / P. A. Correa // Cancer Res. - 1988. - Vol. 48. - P. 3554-3560.</mixed-citation><mixed-citation xml:lang="en">Correa, P. A.Human model of gastric carcinogenesis / P. A. Correa // Cancer Res. - 1988. - Vol. 48. - P. 3554-3560.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Correa, P.Human gastric carcinogenesis: a multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention / P. A. Correa // Cancer Res. - 1992. - Vol. 52. - P.6735-6740.</mixed-citation><mixed-citation xml:lang="en">Correa, P.Human gastric carcinogenesis: a multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention / P. A. Correa // Cancer Res. - 1992. - Vol. 52. - P.6735-6740.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Schistosomes, liver flukes and Helicobacter pylori. // IARC Monogr.Eval. Carcinog. Risks Hum. Lyon, 7-14 June 1994. - Vol. 61. - P. 1-241.</mixed-citation><mixed-citation xml:lang="en">IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Schistosomes, liver flukes and Helicobacter pylori. // IARC Monogr.Eval. Carcinog. Risks Hum. Lyon, 7-14 June 1994. - Vol. 61. - P. 1-241.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Management of Helicobacter pylori infection - the Maastricht V/Florence Consensus Report / P. Malfertheiner [et al.] // Gut. - 2017. -Vol. 66 (1). - P. 6-30.</mixed-citation><mixed-citation xml:lang="en">Management of Helicobacter pylori infection - the Maastricht V/Florence Consensus Report / P. Malfertheiner [et al.] // Gut. - 2017. -Vol. 66 (1). - P. 6-30.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Long-term follow-up study of gastric adenoma /dysplasia. / H. Yamada[et al.] // Endoscopy. - 2004. -Vol. 36. - P. 390-396.</mixed-citation><mixed-citation xml:lang="en">Long-term follow-up study of gastric adenoma /dysplasia. / H. Yamada[et al.] // Endoscopy. - 2004. -Vol. 36. - P. 390-396.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Helicobacter pylori infection,serum pepsinogen level and gastric cancer: a case-control study in Japan / H. Fukuda [et al.] // Jpn. J. Cancer Res. - 1995. -Vol. 86. - P. 64-71.</mixed-citation><mixed-citation xml:lang="en">Helicobacter pylori infection,serum pepsinogen level and gastric cancer: a case-control study in Japan / H. Fukuda [et al.] // Jpn. J. Cancer Res. - 1995. -Vol. 86. - P. 64-71.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Kodoi, A.Serum pepsinogen in screening for gastric cancer. / A. Kodoi [et al.] // J. Gastroenterol. - 1995. -Vol. 30. - P. 452-460.</mixed-citation><mixed-citation xml:lang="en">Kodoi, A.Serum pepsinogen in screening for gastric cancer. / A. Kodoi [et al.] // J. Gastroenterol. - 1995. -Vol. 30. - P. 452-460.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Manegement of precancerous conditions and lesions in stomach (MAPS): guideline from the European Society of Gastroinyestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Patology (ESP), and the Sociedade Portuguesa de EndoscopiaDigestiva (SPED) / M. Dinis-Ribeiro [et al.] // Endoscopy. - 2012. - Vol. 44. - P. 74-94.</mixed-citation><mixed-citation xml:lang="en">Manegement of precancerous conditions and lesions in stomach (MAPS): guideline from the European Society of Gastroinyestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Patology (ESP), and the Sociedade Portuguesa de EndoscopiaDigestiva (SPED) / M. Dinis-Ribeiro [et al.] // Endoscopy. - 2012. - Vol. 44. - P. 74-94.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Classification and grading of gastritis. The update Sydney System. International Workshop on the Histopathology of gastritis. Houston 1994 / M. F. Dixon [et al.] // Am J SurgPathol. - 1994. - Vol. 20. - P. 1161-1181.</mixed-citation><mixed-citation xml:lang="en">Classification and grading of gastritis. The update Sydney System. International Workshop on the Histopathology of gastritis. Houston 1994 / M. F. Dixon [et al.] // Am J SurgPathol. - 1994. - Vol. 20. - P. 1161-1181.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Gastritis staging in clinical practice: the OLGA staging system / M. Rugge [et al.] //Gut. - 2007. - Vol. 56. - P. 631.</mixed-citation><mixed-citation xml:lang="en">Gastritis staging in clinical practice: the OLGA staging system / M. Rugge [et al.] //Gut. - 2007. - Vol. 56. - P. 631.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">OLGA staging for gastritis: a tutorial / M. Rugge [et al.] // Dig Liver Dis. - 2008. - Vol. 40. - P. 650.</mixed-citation><mixed-citation xml:lang="en">OLGA staging for gastritis: a tutorial / M. Rugge [et al.] // Dig Liver Dis. - 2008. - Vol. 40. - P. 650.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Helicobacter pylori - a conundrum of genetic diversity / D. G. Marshall[et al.]// Microbiology. - 1988. - Vol.144. - P. 2925-2939.</mixed-citation><mixed-citation xml:lang="en">Helicobacter pylori - a conundrum of genetic diversity / D. G. Marshall[et al.]// Microbiology. - 1988. - Vol.144. - P. 2925-2939.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">European multicentre survey of in vitro antimicrobial resistance in Helicobacter pylori / Y. Glupczynski[et al.]// Eur J ClinMicrobiol Infect Dis. - 2001. - Vol.20. - P. 820-823.</mixed-citation><mixed-citation xml:lang="en">European multicentre survey of in vitro antimicrobial resistance in Helicobacter pylori / Y. Glupczynski[et al.]// Eur J ClinMicrobiol Infect Dis. - 2001. - Vol.20. - P. 820-823.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Sipponen, P.Atrophic chronic gastritis and intestinal metaplasia in gastric cancer: comparison with a representative population sample /P. Sipponen, M. Kekki, M. Siurali // Cancer. - Vol.52. - P. 1062-1068.</mixed-citation><mixed-citation xml:lang="en">Sipponen, P.Atrophic chronic gastritis and intestinal metaplasia in gastric cancer: comparison with a representative population sample /P. Sipponen, M. Kekki, M. Siurali // Cancer. - Vol.52. - P. 1062-1068.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
