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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2017-14-1-1</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1754</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>МОДЕЛИРОВАНИЕ ГЕМОРРАГИЧЕСКОГО ШОКА</article-title><trans-title-group xml:lang="en"><trans-title>MODELING OF HEMORRHAGIC SHOCK</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зыблев</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Zyblev</surname><given-names>S. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дундаров</surname><given-names>З. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dundarov</surname><given-names>Z. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зыблева</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zybleva</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Республиканский научно-практический центр радиационной медицины и экологии человека</institution></aff><aff xml:lang="en"><institution>Republican Research Center for Radiation Medicine and Human Ecology</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2017</year></pub-date><volume>0</volume><issue>1</issue><fpage>4</fpage><lpage>6</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зыблев С.Л., Дундаров З.А., Зыблева С.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Зыблев С.Л., Дундаров З.А., Зыблева С.В.</copyright-holder><copyright-holder xml:lang="en">Zyblev S.L., Dundarov Z.A., Zybleva S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1754">https://journal.gsmu.by/jour/article/view/1754</self-uri><abstract><p>В настоящее время для воспроизведения геморрагического шока наибольшее распространение получил метод Уиггерса. Предложенная модель до известной степени искусственна и имеет свои недостатки в результате введения гепарина, который предупреждает свертывание крови в мелких сосудах и изменяет сосудистую проницаемость. В ряде случаев геморрагический шок воспроизводится однократным массивным кровопусканием, а дальнейшее течение процесса специально не регулируется. Воспроизведение геморрагического шока по вышеупомянутому методу у мелких лабораторных животных невозможно в связи с малым диаметром магистральных сосудов. Использование крупных лабораторных животных требует высоких материальных затрат. В литературных источниках описано несколько приемов забора крови у крыс. Но известные методы забора крови не могут в полной мере воспроизводить геморрагический шок. Разработка новой модели воспроизведения экспериментального геморрагического шока у мелких лабораторных животных является актуальным направлением в современной экспериментальной хирургии.</p></abstract><trans-abstract xml:lang="en"><p>Wiggers` method has currently become the most wide-spread method of modeling hemorrhagic shock. The proposed model is artificial to a certain degree and has its drawbacks related to the introduction of heparin, which prevents blood coagulation in small vessels and changes the vascular permeability. In a number of cases, hemorrhagic shock was reproduced by a single massive bloodletting, and the further course of the process was not controlled. The modeling of hemorrhagic shock by means of the above-mentioned method is impossible in small laboratory animals due to the small diameter of great vessels. However, the use of large laboratory animals demands high material costs. Several methods of blood sampling have been described in literature sources. However, the known methods of blood sampling cannot reproduce hemorrhagic shock in full measure. The development of a new method of modeling hemorrhagic shock in small laboratory animals is a topical area in modern experimental surgery.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>экспериментальная модель</kwd><kwd>геморрагический шок</kwd><kwd>experimental model</kwd><kwd>hemorrhagic shock</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rodent Anesthesia Wetlab 26th Annual Conference and Trade Show Saskatchewan Association of Veterinary Technologists Inc / Dr Colette Wheler, Ms Peggy Nelles, Ms Nadine Schueller, Ms Carla Hudy // Saskatoon. - 2010. - November 5-7.</mixed-citation><mixed-citation xml:lang="en">Rodent Anesthesia Wetlab 26th Annual Conference and Trade Show Saskatchewan Association of Veterinary Technologists Inc / Dr Colette Wheler, Ms Peggy Nelles, Ms Nadine Schueller, Ms Carla Hudy // Saskatoon. - 2010. - November 5-7.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Кулагин, В. 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