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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2014-11-4-16</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1556</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>МАРКЕРЫ НЕКОТОРЫХ ОППОРТУНИСТИЧЕСКИХ ИНФЕКЦИЙ У ВИЧ-ИНФИЦИРОВАННЫХ ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>MARKERS OF CERTAIN OPPORTUNISTIC INFECTIONS IN HIV-POSITIVE CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анищенко</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Anischenko</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Красавцев</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasavtsev</surname><given-names>E. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кармазин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Karmazin</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казначеева</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaznacheyeva</surname><given-names>E. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Гомельская областная клиническая инфекционная больница</institution></aff><aff xml:lang="en"><institution>Gomel Regional Clinical Infectious Hospital</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2014</year></pub-date><volume>0</volume><issue>4</issue><fpage>80</fpage><lpage>84</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Анищенко Е.В., Красавцев Е.Л., Кармазин В.В., Казначеева Е.П., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Анищенко Е.В., Красавцев Е.Л., Кармазин В.В., Казначеева Е.П.</copyright-holder><copyright-holder xml:lang="en">Anischenko E.V., Krasavtsev E.L., Karmazin V.V., Kaznacheyeva E.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1556">https://journal.gsmu.by/jour/article/view/1556</self-uri><abstract><p>В работе приведены данные о частоте встречаемости маркеров некоторых оппортунистических инфекций у детей, инфицированных ВИЧ вертикальным путем, находящихся на учете в областном консультативно-диспансерном кабинете ВИЧ/СПИД Гомельской областной инфекционной клинической больницы и, в группе детей, рожденных не ВИЧ-инфицированными матерями. У ВИЧ-инфицированных детей достоверно чаще при сравнении с группой ВИЧ-негативных детей встречалась ДНК вируса Эпштейн-Барра (43 %, у здоровых детей - 26 %, р = 0,008). В группе ВИЧ-негативных детей достоверно чаще выявлялись Ig G к цитомегаловирусу (50 %, у ВИЧ-инфицированных детей - 12 %, р = 0,02). ДНК вируса простого герпеса 1 и 2 типа в группах обследуемых детей не выявлялась. Также у детей не были выявлены Ig М к антигенам токсоплазмоза, цитомегаловируса, вируса простого герпеса 1 и 2 типов.</p></abstract><trans-abstract xml:lang="en"><p>The paper presents data on the prevalence of markers of certain opportunistic infections in both HIV-positive children infected via vertical transmission and registered at the HIV/AIDS outpatient consultative ward of the Gomel Regional Infectious Clinical Hospital and in HIV-negative children. The HIV-positive children (43 %) in comparison to the HIV-negative children (26 %, p = 0.008) detected EBV DNA significantly more often. However, the group of the HIV-negative children revealed CMV Ig G more often (50 % vs. 12 % in HIV-positive, p = 0,02). HSV1/2 DNA in the study groups of the children was not detected. The children did not detect Ig M to toxoplasmosis atibodies). CMV, HSV 1/2.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ВИЧ-инфекция</kwd><kwd>дети</kwd><kwd>оппортунистические инфекции</kwd><kwd>HIV-infection</kwd><kwd>children</kwd><kwd>opportunistic infections</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бартлетт, Дж. Клинические аспекты ВИЧ-инфекции. 2009-2010 / Дж. Бартлетт, Дж. Галлант, П. Фам. - М.: Р. Валент, 2010. - 490 с.</mixed-citation><mixed-citation xml:lang="en">Бартлетт, Дж. Клинические аспекты ВИЧ-инфекции. 2009-2010 / Дж. Бартлетт, Дж. Галлант, П. Фам. - М.: Р. Валент, 2010. - 490 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Textbook of pediatric HIV care / S. Zeichner [et al.] - Cambrige, 2005. - 784 p.</mixed-citation><mixed-citation xml:lang="en">Textbook of pediatric HIV care / S. Zeichner [et al.] - Cambrige, 2005. - 784 p.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Рахманова, А. Г. ВИЧ-инфекция у детей / А. Г. Рахманова, Е. Е. Воронин, Ю. А. Фомин. - СПб.: Питер, 2003. - 448 с.</mixed-citation><mixed-citation xml:lang="en">Рахманова, А. Г. ВИЧ-инфекция у детей / А. Г. Рахманова, Е. Е. Воронин, Ю. А. Фомин. - СПб.: Питер, 2003. - 448 с.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Gona, P. Incidence of opportunistic and other infections in HIVinfected children in the HAART era / P. Gona, R. B. Van Dyke, P. L. Williams // Journal of the American Medical Association. - 2006. - P. 292-300.</mixed-citation><mixed-citation xml:lang="en">Gona, P. Incidence of opportunistic and other infections in HIVinfected children in the HAART era / P. Gona, R. B. Van Dyke, P. L. Williams // Journal of the American Medical Association. - 2006. - P. 292-300.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Heng, M. C. Co-infection and synergy of human immunodeficiency virus-1 and herpes simplex virus-1 / M. C. Heng, S. Y. Heng, S. G. Allen // Lancet. - 1994. - Vol. 343. - P. 255-258.</mixed-citation><mixed-citation xml:lang="en">Heng, M. C. Co-infection and synergy of human immunodeficiency virus-1 and herpes simplex virus-1 / M. C. Heng, S. Y. Heng, S. G. Allen // Lancet. - 1994. - Vol. 343. - P. 255-258.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Rapid progression of HIV disease in children with cytomegalovirus DNAemia / G. Nigro [et al.] // AIDS. - 1996. - Vol. 10. - P. 1127-1133.</mixed-citation><mixed-citation xml:lang="en">Rapid progression of HIV disease in children with cytomegalovirus DNAemia / G. Nigro [et al.] // AIDS. - 1996. - Vol. 10. - P. 1127-1133.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Германенко, И. Г. Цитомегаловирусная инфекция: этиология, патогенез, клиника, диагностика, лечение / И. Г. Германенко, А. П. Кудин. - Минск: Зималлето, 2009. - С. 4-7, 11-12.</mixed-citation><mixed-citation xml:lang="en">Германенко, И. Г. Цитомегаловирусная инфекция: этиология, патогенез, клиника, диагностика, лечение / И. Г. Германенко, А. П. Кудин. - Минск: Зималлето, 2009. - С. 4-7, 11-12.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Montoya, J. G. Toxoplasma gondii / J. G. Montoya, J. S. Remington // Principles and Practice of Infectious Diseases / Ed. G. L. Mandell, J. E. Bennett, R. Dolin. - Philadelphia: Churchill Livingstone, 2000. - P. 2858-2888.</mixed-citation><mixed-citation xml:lang="en">Montoya, J. G. Toxoplasma gondii / J. G. Montoya, J. S. Remington // Principles and Practice of Infectious Diseases / Ed. G. L. Mandell, J. E. Bennett, R. Dolin. - Philadelphia: Churchill Livingstone, 2000. - P. 2858-2888.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Оптимизация подходов к наблюдению и лечению детей с ВИЧ/СПИДом (инструкция по применению): утв. Мин-вом здравоохранения Республики Беларусь 10.09.2008. - Минск, 2008. - 100 с.</mixed-citation><mixed-citation xml:lang="en">Оптимизация подходов к наблюдению и лечению детей с ВИЧ/СПИДом (инструкция по применению): утв. Мин-вом здравоохранения Республики Беларусь 10.09.2008. - Минск, 2008. - 100 с.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Report of the technical consultation on clinical staging of HIV/AIDS and HIV/AIDS case definition for surveillance. Copenhagen, WHO Regional Office for Europe, 2005. - http://www.euro. who.int/document/E87956.pdf, accessed 19 December 2006).</mixed-citation><mixed-citation xml:lang="en">Report of the technical consultation on clinical staging of HIV/AIDS and HIV/AIDS case definition for surveillance. Copenhagen, WHO Regional Office for Europe, 2005. - http://www.euro. who.int/document/E87956.pdf, accessed 19 December 2006).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
