zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2013-10-4-5zdor-1425Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESПЕРВИЧНЫЙ ГИПЕРПАРАТИРЕОЗ (обзор литературы)PRIMARY HYPERPARATHYROIDISM (literature review)БорсукА. Д.BorsukA. D.noemail@neicon.ruРеспубликанский научно-практический центр радиационной медицины и экологии человека, г. ГомельRepublican Research Centre for Radiation Medicine and Human Ecology, Gomel201328122013043340Copyright © Борсук А.Д., 20132013Борсук А.Д.Borsuk A.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/1425

Первичный гиперпаратиреоз является распространенным эндокринологическим заболеванием у взрослых, типичным проявлением которого является бессимптомная гиперкальциемия. Первичный гиперпаратиреоз проявляется клинически у более молодых пациентов, у которых можно обнаружить признаки гиперкальциемии, осложнения со стороны опорно-двигательного аппарата и (или) нефролитиаз. В большинстве случаев первичный гиперпаратиреоз возникает вследствие солитарной доброкачественной аденомы паращитовидных желез, редко - множественных аденом. Вовлечение всех четырех паращитовидных желез, так называемая паратиреоидная гиперплазия, встречается у 10 % пациентов. Карцинома паращитовидных желез является редким заболеванием (распространенность менее 1 %). Основным методом лечения взрослых пациентов с первичным гиперпаратиреозом является хирургический, за исключением случаев, ассоциированных с наследственной гипокальциурической гиперкальциемией.

Primary hyperparathyroidism is a common endocrine disorder in adults and asymptomatic hypercalcemia is its typical manifestation. Primary hyperparathyroidism is clinically symptomatic in younger patients who reveal signs of hypercalcemia, skeletal complications and/or nephrolithiasis. In most cases, primary hyperparathyroidism is caused by a solitary benign parathyroid adenoma, rarely by multiple adenomas. The involvement of all the four parathyroid glands, so-called parathyroid hyperplasia, occurs in approximately 10 % cases. Parathyroid carcinoma is exceedingly uncommon (less than 1 %). Surgery is the principal treatment method for most adult patients with primary hyperparathyroidism, apart from the cases associated with hereditary hypocalciuric hypercalcemia.

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The authors declare that there are no conflicts of interest present.