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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2013-10-1-7</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1336</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>БИОЛОГИЧЕСКИЕ АСПЕКТЫ АПОПТОЗА (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>BIOLOGICAL ASPECTS OF APOPTOSIS (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фомченко</surname><given-names>Н. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Fomchenko</surname><given-names>N. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воропаев</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Voropayev</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2013</year></pub-date><volume>0</volume><issue>1</issue><fpage>39</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фомченко Н.Е., Воропаев Е.В., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Фомченко Н.Е., Воропаев Е.В.</copyright-holder><copyright-holder xml:lang="en">Fomchenko N.E., Voropayev E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1336">https://journal.gsmu.by/jour/article/view/1336</self-uri><abstract><p>Проблема исследования апоптоза и его взаимосвязь с различными заболеваниями является актуальной в биологии и медицине. Апоптоз - это сложный и многогранный механизм, который возник в процессе эволюции с момента появления многоклеточных организмов, служит в целях регуляции естественного баланса между размножением и гибелью клеток и является необходимым условием поддержания гомеостаза, устанавливает определенные взаимоотношения между отдельными клетками в целостном организме. Благодаря этим взаимоотношениям клетки вступают в различные этапы жизненного цикла - деления, роста, развития, дифференцировки, старения и гибели. Апоптоз является широко распространенным общебиологическим механизмом, ответственным не только за поддержание постоянства численности клеток, формообразование, выбраковку дефектных клеток, но и за развитие различных патологических состояний отдельных клеток, систем и организма в целом.</p></abstract><trans-abstract xml:lang="en"><p>The problem of studying apoptosis and its relations with various diseases is relevant in both biology and medicine. Apoptosis is a complex and multifaceted phenomenon, which arose in the course of evolution since the emergence of multicellular organisms and serves to regulate the natural balance between the birth and death of cells being a necessary condition for the maintenance of homeostasis, and in this way establishes certain relations between individual cells in the whole organism. Due to these relations cells enter different stages of the life cycle: division, growth, development, differentiation, aging and death. Apoptosis is a common general biological mechanism responsible not only for maintaining constant number of cells, forming, culling of defective cells, but also for the development of various pathological conditions of individual cells, systems, and body as a whole.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>апоптоз</kwd><kwd>причины апоптоза и его регуляция</kwd><kwd>онтогенез</kwd><kwd>заболевания</kwd><kwd>apoptosis</kwd><kwd>apoptosis causes and regulation</kwd><kwd>ontogeny</kwd><kwd>diseases</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Narayanan, V. Apoptosis in development of the nervous system. Naturally occurring death in the developing nervous system / V. Narayanan // Pediatr Neurol. - 1997. - Vol. 16. - P. 9-13.</mixed-citation><mixed-citation xml:lang="en">Narayanan, V. Apoptosis in development of the nervous system. 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