<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2012-9-3-1</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1272</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>ХРОНИЧЕСКАЯ СЕРДЕЧНАЯ НЕДОСТАТОЧНОСТЬ С СОХРАНЕННОЙ ФРАКЦИЕЙ ВЫБРОСА ЛЕВОГО ЖЕЛУДОЧКА (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>CHRONIC HEART DEFICIENCY WITH PRESERVED LEFT VENTRICLE EJECTION FRACTION (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бакалец</surname><given-names>Н. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Bakalets</surname><given-names>N. F.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2012</year></pub-date><volume>0</volume><issue>3</issue><fpage>7</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бакалец Н.Ф., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Бакалец Н.Ф.</copyright-holder><copyright-holder xml:lang="en">Bakalets N.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1272">https://journal.gsmu.by/jour/article/view/1272</self-uri><abstract><p>В обзоре литературы отражены вопросы эпидемиологии, патофизиологии, клинической картины, диагностики и лечения хронической сердечной недостаточности с сохраненной фракцией выброса левого желудочка.</p></abstract><trans-abstract xml:lang="en"><p>The literature review covers the questions of epidemiology, pathogenesis, clinical picture, diagnosis, treatment of chronic heart deficiency with preserved left ventricle ejection fraction.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>сохраненная фракция выброса левого желудочка</kwd><kwd>диастолическая дисфункция левого желудочка</kwd><kwd>chronic heart deficiency</kwd><kwd>preserved left ventricular ejection fraction</kwd><kwd>dyastolic dysfunction of left ventricular</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Напалков, Д. А. Хроническая сердечная недостаточность: смещение фокуса на начальные стадии заболевания / Д. А. Напалков, В. А. Сулимов, Н. М. Сеидов // Лечащий врач. - 2008. - № 4. - С. 14-18.</mixed-citation><mixed-citation xml:lang="en">Напалков, Д. А. Хроническая сердечная недостаточность: смещение фокуса на начальные стадии заболевания / Д. А. Напалков, В. А. Сулимов, Н. М. Сеидов // Лечащий врач. - 2008. - № 4. - С. 14-18.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Levy, D. Echocardiographically detected left ventricular hypertrophy: prevalence and risk factor. The Framingham Heart Study / D. Levy, K. Anderson, D. Savage // Ann Intern Med. - 1988. - Vol. 108. - P. 7-14.</mixed-citation><mixed-citation xml:lang="en">Levy, D. Echocardiographically detected left ventricular hypertrophy: prevalence and risk factor. The Framingham Heart Study / D. Levy, K. Anderson, D. Savage // Ann Intern Med. - 1988. - Vol. 108. - P. 7-14.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Беленков, Ю. Д. Распостраненность хронической сердечной недостаточности в Европейской части РФ (данные исследования «ЭПОХА - ХСН») / Ю. Н. Беленков, И. В. Фомин, Ю. Д. Мареев // ЖСН. - 2006. - Т. 3, № 7. - С. 112-115.</mixed-citation><mixed-citation xml:lang="en">Беленков, Ю. Д. Распостраненность хронической сердечной недостаточности в Европейской части РФ (данные исследования «ЭПОХА - ХСН») / Ю. Н. Беленков, И. В. Фомин, Ю. Д. Мареев // ЖСН. - 2006. - Т. 3, № 7. - С. 112-115.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Owan, T. E. Trends in Prevalence and Outcome of Heart Failure with Preserved Ejection Fraction / T. E. Owan, D. O. Hodge, R. M. Herges // N Engl J Med. - 2006. - № 7. - Р. 251-259.</mixed-citation><mixed-citation xml:lang="en">Owan, T. E. Trends in Prevalence and Outcome of Heart Failure with Preserved Ejection Fraction / T. E. Owan, D. O. Hodge, R. M. Herges // N Engl J Med. - 2006. - № 7. - Р. 251-259.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Bratia, R. S. Outcome of Heart Fallure with Preserved Ejection Fraction in a Population-Based Study / R. S. Bratia, J. V. Tu, D. S. Lee // N Engl J Med. - 2006. - № 7. - Р. 260-269.</mixed-citation><mixed-citation xml:lang="en">Bratia, R. S. Outcome of Heart Fallure with Preserved Ejection Fraction in a Population-Based Study / R. S. Bratia, J. V. Tu, D. S. Lee // N Engl J Med. - 2006. - № 7. - Р. 260-269.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Lye, M. Heart failure in the elderly: a diastolic problem? / M. Lye, N. Wisniacki // Europ. J Heart failure. - 2000. - Vol. 2, № 2. - P. 133-136.</mixed-citation><mixed-citation xml:lang="en">Lye, M. Heart failure in the elderly: a diastolic problem? / M. Lye, N. Wisniacki // Europ. J Heart failure. - 2000. - Vol. 2, № 2. - P. 133-136.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Yancy, C. W. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function. A report from the acute decompensated heart failure national registry (ADHERE) database / C. W. Yancy, M. Lopatin, L. W. Stevenson // Am Coll Cardiol. J. - 2006. - Vol. 47. - P. 76-84.</mixed-citation><mixed-citation xml:lang="en">Yancy, C. W. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function. A report from the acute decompensated heart failure national registry (ADHERE) database / C. W. Yancy, M. Lopatin, L. W. Stevenson // Am Coll Cardiol. J. - 2006. - Vol. 47. - P. 76-84.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Шутов, А. М. Нарушение функции почек и анемия у больных пожилого возраста с диастолической сердечной недостаточностью / А. М. Шутов, Л. Ю. Тармонова // Тер. архив. - 2007. - № 12. - С. 25-27.</mixed-citation><mixed-citation xml:lang="en">Шутов, А. М. Нарушение функции почек и анемия у больных пожилого возраста с диастолической сердечной недостаточностью / А. М. Шутов, Л. Ю. Тармонова // Тер. архив. - 2007. - № 12. - С. 25-27.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Fonarow, G. C. For the OPTIMIZE-HF investigators and hospitals. Characteristics, treatments and outcomes of patients with preserved systolic function hospitazed for heart failure / G. C. Fonarow, W. G. Stough, W. T. Abraham // Am Coll Cardiol. J. - 2007. - Vol. 50. - P. 768-777.</mixed-citation><mixed-citation xml:lang="en">Fonarow, G. C. For the OPTIMIZE-HF investigators and hospitals. Characteristics, treatments and outcomes of patients with preserved systolic function hospitazed for heart failure / G. C. Fonarow, W. G. Stough, W. T. Abraham // Am Coll Cardiol. J. - 2007. - Vol. 50. - P. 768-777.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Philbin, E. F. A. report from the MISCHF / E. F. Philbin // Am J Med. - 2000. - Vol. 109. - P. 605-613.</mixed-citation><mixed-citation xml:lang="en">Philbin, E. F. A. report from the MISCHF / E. F. Philbin // Am J Med. - 2000. - Vol. 109. - P. 605-613.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Triboulloy, C [et al.] // Eur Heart J. - 2008. - Vol. 29. - P. 339-347.</mixed-citation><mixed-citation xml:lang="en">Triboulloy, C [et al.] // Eur Heart J. - 2008. - Vol. 29. - P. 339-347.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Christopher, A. P. The Role of Left Atrial Function in Diastolic Heart Failure / P. A. Christopher, J. K. Sandor // Circ Cardiovasc Imaging. - 2009. - Vol. 2. - P. 6-9.</mixed-citation><mixed-citation xml:lang="en">Christopher, A. P. The Role of Left Atrial Function in Diastolic Heart Failure / P. A. Christopher, J. K. Sandor // Circ Cardiovasc Imaging. - 2009. - Vol. 2. - P. 6-9.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Агеев, Ф. Т. Диастолическая сердечная недостаточность: 10 лет знакомства / Ф. Т. Агеев // Сердечная недостаточность. - 2010. - № 11. - С. 5-6.</mixed-citation><mixed-citation xml:lang="en">Агеев, Ф. Т. Диастолическая сердечная недостаточность: 10 лет знакомства / Ф. Т. Агеев // Сердечная недостаточность. - 2010. - № 11. - С. 5-6.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Беленков, Ю. Н. Знакомьтесь: диастолическая сердечная недостаточность / Ю. Н. Беленков, Ф. Т. Агеев, В. Ю. Мареев // Сердечная недостаточность. - 2000. - № 1. - С. 40-46.</mixed-citation><mixed-citation xml:lang="en">Беленков, Ю. Н. Знакомьтесь: диастолическая сердечная недостаточность / Ю. Н. Беленков, Ф. Т. Агеев, В. Ю. Мареев // Сердечная недостаточность. - 2000. - № 1. - С. 40-46.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Капелько, В. И. Диастолическая дисфункция / В. И. Капелько // Кардиология. - 2011. - T. 51, № 1. - С. 79-90.</mixed-citation><mixed-citation xml:lang="en">Капелько, В. И. Диастолическая дисфункция / В. И. Капелько // Кардиология. - 2011. - T. 51, № 1. - С. 79-90.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Драпкина, О. М. Хроническая сердечная недостаточность с сохраненной фракцией выброса: патофизиология, диагностика, стратегии лечения / О. М. Драпкина, Я. И. Ашихмин // Кардиология. - 2009. - T. 49, № 9. - С. 90-95.</mixed-citation><mixed-citation xml:lang="en">Драпкина, О. М. Хроническая сердечная недостаточность с сохраненной фракцией выброса: патофизиология, диагностика, стратегии лечения / О. М. Драпкина, Я. И. Ашихмин // Кардиология. - 2009. - T. 49, № 9. - С. 90-95.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Атрощенко, Е. С. Диагностика и лечение хронической сердечной недостаточности. Национальные рекомендцации / Е. С. Атрощенко, Е. К. Курляндская. - Минск: Беларусь, 2010. - 64 с.</mixed-citation><mixed-citation xml:lang="en">Атрощенко, Е. С. Диагностика и лечение хронической сердечной недостаточности. Национальные рекомендцации / Е. С. Атрощенко, Е. К. Курляндская. - Минск: Беларусь, 2010. - 64 с.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Siegentaler, W. Differential diagnosis in internal medicine / W. Siegentaler. - Stuttgart: Thieme, 2007. - Р. 1104.</mixed-citation><mixed-citation xml:lang="en">Siegentaler, W. Differential diagnosis in internal medicine / W. Siegentaler. - Stuttgart: Thieme, 2007. - Р. 1104.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Vasan, R. S. Defining diastolic heart failure: A call for standardized diagnostic criteria / R. S. Vasan, D. Levy // Circulation. - 2002. - Vol. 102. - P. 2118.</mixed-citation><mixed-citation xml:lang="en">Vasan, R. S. Defining diastolic heart failure: A call for standardized diagnostic criteria / R. S. Vasan, D. Levy // Circulation. - 2002. - Vol. 102. - P. 2118.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Шиллер, Н. Клиническая эхокардиография / Н. Шиллер, М. А. Осипов. - 2-е изд. - М., 2005. - С. 68-73.</mixed-citation><mixed-citation xml:lang="en">Шиллер, Н. Клиническая эхокардиография / Н. Шиллер, М. А. Осипов. - 2-е изд. - М., 2005. - С. 68-73.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Paulus, W. J. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by Heart Failure and Echocardiography Associations of the European Society of Cardiology / W. J. Paulus, C. Tschope, J. Sanderson // Eur Heart J. - 2007. - Vol. 87. - P. 2539-2550.</mixed-citation><mixed-citation xml:lang="en">Paulus, W. J. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by Heart Failure and Echocardiography Associations of the European Society of Cardiology / W. J. Paulus, C. Tschope, J. Sanderson // Eur Heart J. - 2007. - Vol. 87. - P. 2539-2550.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Zipes [et al.] // Braunwald`s Yeart Disease. - NY, 2007.</mixed-citation><mixed-citation xml:lang="en">Zipes [et al.] // Braunwald`s Yeart Disease. - NY, 2007.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Lenzen, M. Differeces between patients with a preserved and a depressed left ventricular function: a report from the EoroHeart Failure Survey / M. Lenzen, W. Scholte op Reimer, E. Boersma // Eur Heart J. - 2004. - Vol. 25. - P. 1214-1220.</mixed-citation><mixed-citation xml:lang="en">Lenzen, M. Differeces between patients with a preserved and a depressed left ventricular function: a report from the EoroHeart Failure Survey / M. Lenzen, W. Scholte op Reimer, E. Boersma // Eur Heart J. - 2004. - Vol. 25. - P. 1214-1220.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Clelend, J. G. F. The Perindopril in Elderly with Chronic Heart Failure (PEP-CHF) Study / J. G. F. Clelend, M. Tendera, J. Adamus // Eur. Heart J. - 2006. - Vol. 27. - P. 2338-2345.</mixed-citation><mixed-citation xml:lang="en">Clelend, J. G. F. The Perindopril in Elderly with Chronic Heart Failure (PEP-CHF) Study / J. G. F. Clelend, M. Tendera, J. Adamus // Eur. Heart J. - 2006. - Vol. 27. - P. 2338-2345.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Aronow, W. Effekt of enelapril on congestive heart failure treated with diuretics in elderly patients with prior myocardial infarction and normal left ventricular ejection fraction / W. Aronow, I. Kronzon // J Cardiol. - 1993. - Vol. 71. - P. 602-604.</mixed-citation><mixed-citation xml:lang="en">Aronow, W. Effekt of enelapril on congestive heart failure treated with diuretics in elderly patients with prior myocardial infarction and normal left ventricular ejection fraction / W. Aronow, I. Kronzon // J Cardiol. - 1993. - Vol. 71. - P. 602-604.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Carson, P. Mild systolic dysfunction in heart failure: baseline characteristics, prognosis and respons to therapy in the Vasodilator in Heart Failure Trials (V-HeFT) / P. Carson, G. Jonson, R. Fletcher // J Coll Cardiol. - 1996. - Vol. 27. - P. 642-649.</mixed-citation><mixed-citation xml:lang="en">Carson, P. Mild systolic dysfunction in heart failure: baseline characteristics, prognosis and respons to therapy in the Vasodilator in Heart Failure Trials (V-HeFT) / P. Carson, G. Jonson, R. Fletcher // J Coll Cardiol. - 1996. - Vol. 27. - P. 642-649.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Yusuf, S. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial / S. Yusuf, M. Pfeffer, K. Sweberg // Lancet. - 2003. - Vol. 362. - P. 777-781.</mixed-citation><mixed-citation xml:lang="en">Yusuf, S. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial / S. Yusuf, M. Pfeffer, K. Sweberg // Lancet. - 2003. - Vol. 362. - P. 777-781.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Irbesartan in Patientes with Heart Failure and Preserved Ejection Fraction / B. Massie [et al.] // Engl J Med. - 2008. - Vol. 359. - P. 2456-2467.</mixed-citation><mixed-citation xml:lang="en">Irbesartan in Patientes with Heart Failure and Preserved Ejection Fraction / B. Massie [et al.] // Engl J Med. - 2008. - Vol. 359. - P. 2456-2467.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">The Digitalis Investigation Group. The effect of digoxin on mobidity in patients with heart failure // N. Engl J Med. - 1997. - Vol. 336. - P. 525-533.</mixed-citation><mixed-citation xml:lang="en">The Digitalis Investigation Group. The effect of digoxin on mobidity in patients with heart failure // N. Engl J Med. - 1997. - Vol. 336. - P. 525-533.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Ghio, S. Effect of nebivolol in elderly heart failure patiens with or without systolic left ventricular dysfunction: results of the SENIORS echocardiographic substudy / S. Ghio, G. Magrini, A. Serio // Eur Heart J. - 2006. - Vol. 27. - P. 562-568.</mixed-citation><mixed-citation xml:lang="en">Ghio, S. Effect of nebivolol in elderly heart failure patiens with or without systolic left ventricular dysfunction: results of the SENIORS echocardiographic substudy / S. Ghio, G. Magrini, A. Serio // Eur Heart J. - 2006. - Vol. 27. - P. 562-568.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Bergstrom, A. Carvedilol improves diastolic function in patients with heart failure / A. Bergstrom, B. Andersson, M. Ender // Circulation. - 2001. - Vol. 104. - P. 117.</mixed-citation><mixed-citation xml:lang="en">Bergstrom, A. Carvedilol improves diastolic function in patients with heart failure / A. Bergstrom, B. Andersson, M. Ender // Circulation. - 2001. - Vol. 104. - P. 117.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Lalande, S. Diastolic dysfunction: a linc between hypertension and heart failure / S. Lalande, B. D. Johnson // Drugs Today (Barc). - 2008. - Vol. 44. - P. 503-513.</mixed-citation><mixed-citation xml:lang="en">Lalande, S. Diastolic dysfunction: a linc between hypertension and heart failure / S. Lalande, B. D. Johnson // Drugs Today (Barc). - 2008. - Vol. 44. - P. 503-513.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Relaxin, 2008. Proceeding of the Relaxin and Related Peptides 5th International Conference, May 18-23, 2008, Maui, Hawaii, USA. Ann N Y Acad Sci. 2009. Apr; 1160.</mixed-citation><mixed-citation xml:lang="en">Relaxin, 2008. Proceeding of the Relaxin and Related Peptides 5th International Conference, May 18-23, 2008, Maui, Hawaii, USA. Ann N Y Acad Sci. 2009. Apr; 1160.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Smiseth, O. A. Diastolic heart failure Springer-Verlag / O. A. Smiseth, M. Tendera. - London, 2008.</mixed-citation><mixed-citation xml:lang="en">Smiseth, O. A. Diastolic heart failure Springer-Verlag / O. A. Smiseth, M. Tendera. - London, 2008.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Lehnart, S. E. Adnormalites of calcim metabolism and myocardial contractility depression in the failing heart / S. E. Lehart, L. S. Maier, G. Hasenfuss // Heart Fail Rev. - 2009. - Vol. 14. - P. 213-224.</mixed-citation><mixed-citation xml:lang="en">Lehnart, S. E. Adnormalites of calcim metabolism and myocardial contractility depression in the failing heart / S. E. Lehart, L. S. Maier, G. Hasenfuss // Heart Fail Rev. - 2009. - Vol. 14. - P. 213-224.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
