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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2012-9-2-5</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1247</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>ДЕМЕНЦИЯ СОСУДИСТОГО ГЕНЕЗА: ЭТИОПАТОГЕНЕЗ, КЛИНИКА, ДИАГНОСТИКА, ЛЕЧЕНИЕ</article-title><trans-title-group xml:lang="en"><trans-title>DEMENTIA OF VASCULAR GENESIS: ETIOPATHOGENESIS, CLINICAL FEATURES, DIAGNOSIS, MANAGEMENT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мистюкевич</surname><given-names>Д. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Mistiukevich</surname><given-names>D. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2012</year></pub-date><volume>0</volume><issue>2</issue><fpage>27</fpage><lpage>34</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мистюкевич Д.П., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Мистюкевич Д.П.</copyright-holder><copyright-holder xml:lang="en">Mistiukevich D.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1247">https://journal.gsmu.by/jour/article/view/1247</self-uri><abstract><p>Сосудистая деменция является второй по распространенности формой деменции после болезни Альцгеймера и характеризуется дефицитом когнитивных функций цереброваскулярной природы. В настоящее время существуют противоречия в терминологии, классификации, диагностических критериях, методах лечения сосудистой деменции. Целью профилактических мероприятий является снижение частоты сосудистой деменции посредством воздействия на факторы риска цереброваскулярных заболеваний (первичная профилактика) и лечение пациентов после инсульта (вторичная профилактика). Базисное лечение пациентов с сосудистой деменцией основано на назначении ингибиторов холинэстеразы.</p></abstract><trans-abstract xml:lang="en"><p>Vascular dementia is the second most prevalent form of dementia after Alzheimer's disease and is characterized by the deficit of cognitive functions of cerebrovascular origin. At present, there are still opposing views about terminology, classification and diagnostic criteria, methods of treatment for vascular dementia. The aim of the preventive measures is to reduce vascular dementia prevalence by cerebrovascular disease effect on risk factors (primary prophylaxis), or treating patients after stroke (secondary prevention). The basic management of vascular dementia patients is based on the prescription of cholinesterase inhibitors.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сосудистая деменция</kwd><kwd>когнитивные расстройства</kwd><kwd>болезнь Альцгеймера</kwd><kwd>vascular dementia</kwd><kwd>cognitive impairment</kwd><kwd>Alzheimer's disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дамулин, И. В. Когнитивные расстройства при цереброваскулярной патологии / И. В. Дамулин // Журнал неврологии и психиатрии. - 2009. - № 1. - С. 70-75.</mixed-citation><mixed-citation xml:lang="en">Дамулин, И. В. Когнитивные расстройства при цереброваскулярной патологии / И. В. Дамулин // Журнал неврологии и психиатрии. - 2009. - № 1. - С. 70-75.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Шахпаронова, Н. В. Медикаментозная коррекция когнитивных нарушений сосудистого генеза / Н. В. Шахпаронова, А. С. Кадыков // Нервные болезни. - 2008. - № 2. - С. 17-20.</mixed-citation><mixed-citation xml:lang="en">Шахпаронова, Н. В. Медикаментозная коррекция когнитивных нарушений сосудистого генеза / Н. В. Шахпаронова, А. С. Кадыков // Нервные болезни. - 2008. - № 2. - С. 17-20.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Дамулин, И. В. Сосудистая деменция: патогенез, диагностика и лечение / И. В. Дамулин // Фарматека. - 2010. - № 7. - С. 13-18.</mixed-citation><mixed-citation xml:lang="en">Дамулин, И. В. Сосудистая деменция: патогенез, диагностика и лечение / И. В. Дамулин // Фарматека. - 2010. - № 7. - С. 13-18.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Erkinjuntti, T. Vascular dementia / T. Erkinjuntti, K. Rockwood // Semin Clin Neuropsychiatry. - 2003. - Vol. 8. - Р. 37-45.</mixed-citation><mixed-citation xml:lang="en">Erkinjuntti, T. Vascular dementia / T. Erkinjuntti, K. Rockwood // Semin Clin Neuropsychiatry. - 2003. - Vol. 8. - Р. 37-45.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Jellinger, K. A. The pathology of «vascular dementia»: a critical update / K. A. Jellinger // J. Alzheimers Dis. - 2008. - Vol. 14. - P. 107-123.</mixed-citation><mixed-citation xml:lang="en">Jellinger, K. A. The pathology of «vascular dementia»: a critical update / K. A. Jellinger // J. Alzheimers Dis. - 2008. - Vol. 14. - P. 107-123.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Román, G. C. Facts, myths, and controversies in vascular dementia / G. C. Román // J. Neurol. Sci. - 2004. - Vol. 15. - P. 49-52.</mixed-citation><mixed-citation xml:lang="en">Román, G. C. Facts, myths, and controversies in vascular dementia / G. C. Román // J. Neurol. Sci. - 2004. - Vol. 15. - P. 49-52.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Grand, J. Clinical features and multidisciplinary approaches to dementia care / J. Grand, S. Caspar, W. S. Stuart // J. Multidisciplinary Healthcare. - 2011. - Vol. 4. - Р. 125-147.</mixed-citation><mixed-citation xml:lang="en">Grand, J. Clinical features and multidisciplinary approaches to dementia care / J. Grand, S. Caspar, W. S. Stuart // J. Multidisciplinary Healthcare. - 2011. - Vol. 4. - Р. 125-147.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Buell, J. S. The value of physiologic vitamin D as a biomarker of dementia / J. S. Buell, K. L. Tucker // Drugs Today. - 2011. - Vol. 47. - Р. 223-231.</mixed-citation><mixed-citation xml:lang="en">Buell, J. S. The value of physiologic vitamin D as a biomarker of dementia / J. S. Buell, K. L. Tucker // Drugs Today. - 2011. - Vol. 47. - Р. 223-231.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Vitamin D cognitive dysfunction and dementia in older adults / A. P. Dickens [et al.] // CNS Drugs. - 2011. - Vol. 25. - Р. 629-639.</mixed-citation><mixed-citation xml:lang="en">Vitamin D cognitive dysfunction and dementia in older adults / A. P. Dickens [et al.] // CNS Drugs. - 2011. - Vol. 25. - Р. 629-639.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Román, G. C. Facts, myths, and controversies in vascular dementia / G. C. Román // J. Neurol. Sci. - 2004. - Vol. 15. - P. 49-52.</mixed-citation><mixed-citation xml:lang="en">Román, G. C. Facts, myths, and controversies in vascular dementia / G. C. Román // J. Neurol. Sci. - 2004. - Vol. 15. - P. 49-52.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Erkinjuntti, T. Diagnosis and management of vascular cognitive impairment and dementia / T. Erkinjuntti // J. Neural. Transm. Suppl. - 2002. - Vol. 63. - P. 91-109.</mixed-citation><mixed-citation xml:lang="en">Erkinjuntti, T. Diagnosis and management of vascular cognitive impairment and dementia / T. Erkinjuntti // J. Neural. Transm. Suppl. - 2002. - Vol. 63. - P. 91-109.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Genetic dissection of susceptibility to vascular dementia / Y. Kim [et al.] // Psychiatr Genet. - 2011. - Vol. 21. - Р. 69-76.</mixed-citation><mixed-citation xml:lang="en">Genetic dissection of susceptibility to vascular dementia / Y. Kim [et al.] // Psychiatr Genet. - 2011. - Vol. 21. - Р. 69-76.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Russell, M. B. Genetics of dementia / M. B. Russell // Acta Neurol Scand. - 2010. - Vol. 190. - Р. 58-61.</mixed-citation><mixed-citation xml:lang="en">Russell, M. B. Genetics of dementia / M. B. Russell // Acta Neurol Scand. - 2010. - Vol. 190. - Р. 58-61.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Iadecola, C. The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia / C. Iadecola // Acta Neuropathol. - 2010. - Vol. 120. - P. 287-296.</mixed-citation><mixed-citation xml:lang="en">Iadecola, C. The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia / C. Iadecola // Acta Neuropathol. - 2010. - Vol. 120. - P. 287-296.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Tartaglia, М. С. Neuroimaging in Dementia / М. С. Tartaglia, H. J. Rosen, B. L. Mille // The Journal of the American Society for Experimental Neurotherapeutics. - 2011. - Vol. 8. - P. 82-92.</mixed-citation><mixed-citation xml:lang="en">Tartaglia, М. С. Neuroimaging in Dementia / М. С. Tartaglia, H. J. Rosen, B. L. Mille // The Journal of the American Society for Experimental Neurotherapeutics. - 2011. - Vol. 8. - P. 82-92.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Poon, I. O. Effects of antihypertensive drug treatment on the risk of dementia and cognitive impairment / I. O. Poon // Pharmacotherapy. - 2008. - Vol. 28. - Р. 366-375.</mixed-citation><mixed-citation xml:lang="en">Poon, I. O. Effects of antihypertensive drug treatment on the risk of dementia and cognitive impairment / I. O. Poon // Pharmacotherapy. - 2008. - Vol. 28. - Р. 366-375.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Hypertension is a potential risk factor for vascular dementia: systematic review / S. I. Sharp [et al.] // Int. J. Geriatr. Psychiatry. - 2011. - Vol. 26. - Р. 661-669.</mixed-citation><mixed-citation xml:lang="en">Hypertension is a potential risk factor for vascular dementia: systematic review / S. I. Sharp [et al.] // Int. J. Geriatr. Psychiatry. - 2011. - Vol. 26. - Р. 661-669.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Cerebrospinal fluid markers for differential dementia diagnosis in a large memory clinic cohort / N. S. Schoonenboom [et al.] // Neurology. - 2012. - Vol. 78. - P. 47-54.</mixed-citation><mixed-citation xml:lang="en">Cerebrospinal fluid markers for differential dementia diagnosis in a large memory clinic cohort / N. S. Schoonenboom [et al.] // Neurology. - 2012. - Vol. 78. - P. 47-54.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Smith, E. E. Leukoaraiosis and stroke / E. E. Smith // Stroke. - 2010. - Vol. 41. - Р. 139-143.</mixed-citation><mixed-citation xml:lang="en">Smith, E. E. Leukoaraiosis and stroke / E. E. Smith // Stroke. - 2010. - Vol. 41. - Р. 139-143.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Patel, B. Magnetic resonance imaging in cerebral small vessel disease and its use as a surrogate disease marker / B. Patel, H. S. Markus // Int. J. Stroke. - 2011. - Vol. 6. - Р. 47-59.</mixed-citation><mixed-citation xml:lang="en">Patel, B. Magnetic resonance imaging in cerebral small vessel disease and its use as a surrogate disease marker / B. Patel, H. S. Markus // Int. J. Stroke. - 2011. - Vol. 6. - Р. 47-59.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Jellinger, K. A. Morphologic diagnosis of «vascular dementia» - a critical update / K. A. Jellinger // J. Neurol. Sci. - 2008. - Vol. 270. - P. 1-12.</mixed-citation><mixed-citation xml:lang="en">Jellinger, K. A. Morphologic diagnosis of «vascular dementia» - a critical update / K. A. Jellinger // J. Neurol. Sci. - 2008. - Vol. 270. - P. 1-12.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Statins for the treatment of dementia / B. McGuinness [et al.] // Cochrane Database Syst. Rev. - 2010. - Vol. 4.</mixed-citation><mixed-citation xml:lang="en">Statins for the treatment of dementia / B. McGuinness [et al.] // Cochrane Database Syst. Rev. - 2010. - Vol. 4.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Nutrition and vascular dementia / L. Perez [et al.] // J. Nutr. Health. Aging. - 2012. - Vol. 16. - P. 319-324.</mixed-citation><mixed-citation xml:lang="en">Nutrition and vascular dementia / L. Perez [et al.] // J. Nutr. Health. Aging. - 2012. - Vol. 16. - P. 319-324.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Is physical activity a potential preventive factor for vascular dementia? A systematic review / D. Aarsland [et al.] // Aging. Ment. Health. - 2010. - Vol. 14. - P. 386-395.</mixed-citation><mixed-citation xml:lang="en">Is physical activity a potential preventive factor for vascular dementia? A systematic review / D. Aarsland [et al.] // Aging. Ment. Health. - 2010. - Vol. 14. - P. 386-395.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
