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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2012-9-2-4</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1246</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЕ ВОЗМОЖНОСТИ И ПОДХОДЫ К ЛЕЧЕНИЮ САХАРНОГО ДИАБЕТА ТИПА 2</article-title><trans-title-group xml:lang="en"><trans-title>MODERN MEANS AND APPROACHES TO TREATMENT FOR DIABETES MELLITUS TYPE 2</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каплиева</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kapliyeva</surname><given-names>M. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2012</year></pub-date><volume>0</volume><issue>2</issue><fpage>23</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Каплиева М.П., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Каплиева М.П.</copyright-holder><copyright-holder xml:lang="en">Kapliyeva M.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1246">https://journal.gsmu.by/jour/article/view/1246</self-uri><abstract><p>Лечение сахарного диабета (СД 2), направленное на достижение устойчивой компенсации заболевания по показателям тощаковой, постпрандиальной и ночной гликемии, а также гликированного гемоглобина (HbА1С), должно включать участие врача и, прежде всего, самого пациента. Важнейшим принципом этиотропного лечения СД 2 является изменение образа жизни, что включает диетотерапию и режим физической активности, которые назначаются всем без исключения больным СД 2 от момента установления диагноза и до конца активной жизни при любой схеме медикаментозного лечения СД 2, но требуют усилий воли самого пациента. Медикаментозное лечение СД 2 направлено на патогенетические звенья: преодоление инсулинорезистентности и стимуляцию эндогенной секреции инсулина, а при ее истощении применяется заместительная инсулинотерапия. Все антидиабетические препараты делятся на три основные группы: инсулинсенситизаторы - препараты против инсулинорезистентности; секретагоги - препараты, стимулирующие эндогенную секрецию инсулина и инсулины.</p></abstract><trans-abstract xml:lang="en"><p>The treatment for diabetes mellitus (DM 2), aimed to achieve firm compensation of the disease on the indicators of fasten, postprandial and night glycemia, as well as glycohemoglobin (HbА1С) must include the participation of the physician and, first of all, the patients themselves. The most important principle of DM 2 etiotropic treatment is a changed lifestyle that includes dietotherapy and physical activity mode. They are prescribed to all DM 2patients without exception since the moment of diagnosis and until the end of active life in any scheme of medical DM 2 treatment, but requires a lot of patients` effort. The DM 2 treatment is concentrated on patogenetical section: to overcome insulin resistance and stimulate endogen insulin secretions, but in case of its exhaustion, substitutive insulin therapy is used. All antidiabetic medicines are divided into three main groups: insulin sensitisers used for insulin resistance; secretagogue which stimulate insulin secretion and insulines.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>гипогликемия</kwd><kwd>осложнения</kwd><kwd>компенсация</kwd><kwd>инкретины</kwd><kwd>глюкагоноподобный полипептид-1</kwd><kwd>diabetes mellitus</kwd><kwd>hypoglycemia</kwd><kwd>complications</kwd><kwd>compensation</kwd><kwd>incretins</kwd><kwd>glucogon-like peptide-1</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">International Diabetes Federation. IDF Diabetes Atlas. 4th ed. 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