zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2012-9-1-26zdor-1238Research ArticleЭКСПЕРИМЕНТАЛЬНАЯ МЕДИЦИНА И БИОЛОГИЯEXPERIMENTAL MEDICINE AND BIOLOGYИСПОЛЬЗОВАНИЕ КОМПОЗИЦИЙ НА ОСНОВЕ ТАУРИНА И ЦИНКА ДЛЯ КОРРЕКЦИИ ДИСБАЛАНСА НЕЙРОАКТИВНЫХ АМИНОКИСЛОТ В ГИПОТАЛАМУСЕ КРЫС, ВЫЗВАННОГО ВВЕДЕНИЕМ АЦЕТАТА СВИНЦАAPPLICATION OF TAURINE- AND ZINC-BASED COMPOSITIONS TO CORRECT LEAD-ASSOCIATED NEUROACTIVE AMINOACID DYSBALANCE IN HYPOTHALAMUS OF RATSЛяхИ. В.LiakhI. V.noemail@neicon.ruДорошенкоЕ. М.DoroshenkoE. M.noemail@neicon.ruСмирновВ. Ю.SmirnovV. Yu.noemail@neicon.ruШейбакВ. М.SheybakV. M.noemail@neicon.ruГродненский государственный медицинский университетGrodno State Medical University20122803201201130135Copyright © Лях И.В., Дорошенко Е.М., Смирнов В.Ю., Шейбак В.М., 20122012Лях И.В., Дорошенко Е.М., Смирнов В.Ю., Шейбак В.М.Liakh I.V., Doroshenko E.M., Smirnov V.Y., Sheybak V.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/1238

Показаны изменения уровней нейроактивных аминокислот в гипоталамусе крыс после введения ацетата свинца и проанализирована эффективность применения композиций на основе таурина и цинка. Наилучшие результаты показаны при использовании композиции, состоящей из таурина и сульфата цинка, в соотношении 4:1.

The changes in the levels of neuroactive amino acids in hypothalamus of rats after lead acetate introduction has been shown and the efficacy of taurine- and zinc-based drug compositions to correct the changes has been analyzed. The mixture consisting of taurine and zinc sulfate in a ratio of 4:1 showed the best results.

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The authors declare that there are no conflicts of interest present.