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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2011-8-2s-23</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1199</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Без раздела</subject></subj-group></article-categories><title-group><article-title>АЛЕМТУЗУМАБ В ЛЕЧЕНИИ БОЛЬНЫХС ХРОНИЧЕСКИМ ЛИМФОЛЕЙКОЗОМ</article-title><trans-title-group xml:lang="en"><trans-title>ALEMTUZUMAB IN THE TREATMENT OF PATIENTS WITH CHRONIC LYMPHATIC LEUKEMIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозова</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozova</surname><given-names>O. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>9-я городская клиническая больница</institution></aff><aff xml:lang="en"><institution>Municipal Clinical Hospital № 9</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2011</year></pub-date><volume>0</volume><issue>2S</issue><fpage>69</fpage><lpage>71</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Морозова О.М., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Морозова О.М.</copyright-holder><copyright-holder xml:lang="en">Morozova O.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1199">https://journal.gsmu.by/jour/article/view/1199</self-uri><abstract><p>В статье освещены результаты международных клинических исследований по использованию алемтузумаба у пациентов с хроническим лимфолейкозом, приведены результаты собственного применения алметузумаба как в монотерапии, так и в сочетании с химиопрепаратами (флюдарабином, циклофосфаном). Полученные результаты свидетельствуют о том, что применение алемтузумаба у больных с хроническим лимфолейкозом (ХЛЛ) является эффективным современным методом терапии.</p></abstract><trans-abstract xml:lang="en"><p>The article elucidates the results of the international clinical research into the application of alemtuzumab in patients with chronic lymphatic leukemia (CLL) and presents the results of the application of alemtuzumab both in monotherapy and in the combination with chemomedicines (fludarabin, cyklofosfan). The received results testify that the application of alemtuzumab in CLL patients is an effective up-to-date method of therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический лимфолейкоз</kwd><kwd>моноклональные антитела</kwd><kwd>алемтузумаб</kwd><kwd>chronic lymphatic leukemia</kwd><kwd>homogenious antibodies</kwd><kwd>alemtuzumab</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath- 1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL) / J. Lundin // Blood. - 2002. - Vol. 100 (3). - P. 768-773.</mixed-citation><mixed-citation xml:lang="en">Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath- 1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL) / J. 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Kennedy [et al.] // Blood. - 2002. - Vol. 99. - P. 2245-2247.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
