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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2011-8-4-12</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1159</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>МОРФОФУНКЦИОНАЛЬНЫЕ АСПЕКТЫ ПРИМЕНЕНИЯ ГЛУБОКИХ ВЕН ДЛЯ РЕКОНСТРУКЦИИ АОРТО-ПОДВЗДОШНОГО СЕГМЕНТА В ЭКСПЕРИМЕНТЕ</article-title><trans-title-group xml:lang="en"><trans-title>MORHOLOGICAL AND FUNCTIONAL ASPECTS OF THE APPLICATION OF FEMORAL VEINS FOR AORTOILIAC RECONSTRUCTION IN EXPERIMENT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лызиков</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyzikov</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ачинович</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Achinovich</surname><given-names>S. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Печенкин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pechyonkin</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Гомельский областной клинический онкологический диспансер</institution></aff><aff xml:lang="en"><institution>Gomel Regional Oncologic Dispensary</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2011</year></pub-date><volume>0</volume><issue>4</issue><fpage>70</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лызиков А.А., Ачинович С.Л., Печенкин А.А., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Лызиков А.А., Ачинович С.Л., Печенкин А.А.</copyright-holder><copyright-holder xml:lang="en">Lyzikov A.A., Achinovich S.L., Pechyonkin A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1159">https://journal.gsmu.by/jour/article/view/1159</self-uri><abstract><p>Цель. Изучение функциональной адекватности различных сосудистых кондуитов. Материал и методы. Изучались морфофункциональные свойства бедренной вены в сравнении с поверхностной и искусственным протезом у 12 беспородных собак-самцов весом 15,3 ± 3,7 кг. Всем собакам выполняли подвздошно-бедренное протезирование комбинированным протезом, состоящим из фрагментов бедренной вены, большой подкожной вены и протеза из политетрафторэтилена. Материал получали с интервалом 3 месяца в сроки 3, 6, 9 и 12 месяцев. Для сравнения величин, не подчиняющихся распределению Гаусса, использовался непараметрический метод сравнения двух независимых выборок - U-критерий Манна-Уитни. Результаты и обсуждение. Пик морфофункциональной перестройки, вызванной включением в артериальный кровоток, для венозных кондуитов приходится на интервал от 3 до 6 месяцев с момента имплантации. Изменения бедренной вены наступают раньше, чем в подкожной вене. Дистрофические изменения в бедренной вене выражены слабее, чем в подкожной. Морфофункциональные свойства бедренной вены отличаются от свойств подкожной вены. Пик регенеративных процессов в искусственном протезе приходится на срок 6 месяцев. На более поздних сроках процессы инволюции преобладают над процессами регенерации.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study. To study the functional adequacy of different vascular conduits. Material and methods. The morphological and functional qualities of femoral vein in comparison with those of superficial vein and artificial prosthesis in 12 pedigreeless male dogs weighted 15,3 ± 3,7 kg have been studied. All the dogs underwent ilio-femoral bypass with combined conduit, sewn from the fragments of femoral vein, superficial vein and polytetrafluorinethylene vascular prosthesis. The specimens were obtained in the interval of 3, 6, 9 and 12 months. Mann-Whitney`s U-criterion, a non-parametric method for comparison of two independent samples was applied to compare the quantities that are not subject to Gauss` distribution. Results and discussion. The apex of morphological-functional rebuilding of veins, caused by their involvement in arterial flow, seems to appear in the interval from 3 to 6 months since the implantation. The changes of femoral vein occur earlier then those of subcutaneous vein. The dystrophic signs are less expressed in femoral vein. The morphological-functional properties of femoral vein differ from those of superficial vein. A peak of regenerative processes on the surface of the artificial vascular prosthesis falls on the term of 6 months. The later termed involutive processes prevail over the regenerative processes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бедренная вена</kwd><kwd>подкожная вена</kwd><kwd>искусственный сосудистый протез</kwd><kwd>аутовенозное шунтирование</kwd><kwd>иммуно-гистохимическое исследование</kwd><kwd>616.14:616.136/.137-089</kwd><kwd>femoral vein</kwd><kwd>subcutaneous vein</kwd><kwd>artificial vascular prosthesis</kwd><kwd>autologous vein bypass</kwd><kwd>immunohistochemical assessment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Silyl-heparin adsorption improves the in vivo thromboresistance of carbon-coated polytetrafluoroethylene vascular grafts / J. Laredo [et al.].// Am J Surg. - 2003. - Vol. 186(5). - P. 556-560.</mixed-citation><mixed-citation xml:lang="en">Silyl-heparin adsorption improves the in vivo thromboresistance of carbon-coated polytetrafluoroethylene vascular grafts / J. Laredo [et al.].// Am J Surg. - 2003. - Vol. 186(5). - P. 556-560.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Darling, R. C. Durability of femoropopliteal reconstructions / R. C. Darling, R. R. Linton // Am. J. Surg. - 1972. - Vol. 123. - P. 472.</mixed-citation><mixed-citation xml:lang="en">Darling, R. C. Durability of femoropopliteal reconstructions / R. C. Darling, R. R. Linton // Am. J. Surg. - 1972. - Vol. 123. - P. 472.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">DeWeese, J. A. Autogenous venous grafts ten years later / J. A. DeWeese, C. G. Rob // Surgery. - 1977. - Vol. 82. - P. 775.</mixed-citation><mixed-citation xml:lang="en">DeWeese, J. A. Autogenous venous grafts ten years later / J. A. DeWeese, C. G. Rob // Surgery. - 1977. - Vol. 82. - P. 775.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Effect of off-pump coronary artery bypass surgery on clinical, angiographic, neurocognitive, and quality of life outcomes: randomised controlled trial / Al-Ruzzeh S. [et al.] // BMJ. - 2006. - Vol. 1. - P. 236.</mixed-citation><mixed-citation xml:lang="en">Effect of off-pump coronary artery bypass surgery on clinical, angiographic, neurocognitive, and quality of life outcomes: randomised controlled trial / Al-Ruzzeh S. [et al.] // BMJ. - 2006. - Vol. 1. - P. 236.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Different Vascular Smooth Muscle Cell Apoptosis in the Human Internal Mammary Artery and the Saphenous Vein. Implications for Bypass Graft Disease / Frischknecht K. [et al.] // J Vasc Res. - 2006. - Vol. 29, № 43 (4). - Р. 338-346.</mixed-citation><mixed-citation xml:lang="en">Different Vascular Smooth Muscle Cell Apoptosis in the Human Internal Mammary Artery and the Saphenous Vein. Implications for Bypass Graft Disease / Frischknecht K. [et al.] // J Vasc Res. - 2006. - Vol. 29, № 43 (4). - Р. 338-346.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Interspecies healing of porus arterial prostheses / L. R. Suvage [et al.] // Observations. - 1960-1974, Vol. 109. - P. 698.</mixed-citation><mixed-citation xml:lang="en">Interspecies healing of porus arterial prostheses / L. R. Suvage [et al.] // Observations. - 1960-1974, Vol. 109. - P. 698.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kassab, G. S. Biomechanical Considerations in the Design of Graft / G. S. Kassab, J. A. Navia // The Homeostasis Hypothesis. Ann Rev Biomed Eng. - 2006. - Apr. 19.</mixed-citation><mixed-citation xml:lang="en">Kassab, G. S. Biomechanical Considerations in the Design of Graft / G. S. Kassab, J. A. Navia // The Homeostasis Hypothesis. Ann Rev Biomed Eng. - 2006. - Apr. 19.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Особенности ангиогенеза в раке печени и их прогностическое значение (клинико-иммуногистохимическое исследование) / Д. А. Гранов. [и др.] // Архив патологии. - 2006. - Т. 68, № 6. - С. 6-10.</mixed-citation><mixed-citation xml:lang="en">Особенности ангиогенеза в раке печени и их прогностическое значение (клинико-иммуногистохимическое исследование) / Д. А. Гранов. [и др.] // Архив патологии. - 2006. - Т. 68, № 6. - С. 6-10.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Microvessel density as new prognostic marker after radiotherapy in rectal cancer / S. Svagzdys [et al.] // B. M. J. Cancer. - 2009. - Vol. 9. - P. 1471-1477.</mixed-citation><mixed-citation xml:lang="en">Microvessel density as new prognostic marker after radiotherapy in rectal cancer / S. Svagzdys [et al.] // B. M. J. Cancer. - 2009. - Vol. 9. - P. 1471-1477.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
