zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2011-8-3-8zdor-1125Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEКЛИНИЧЕСКИ ЗНАЧИМЫЕ БАКТЕРИАЛЬНЫЕ ИНФЕКЦИИ ПРИ ЦИРРОЗЕ ПЕЧЕНИCLINICALLY IMPORTANT BACTERIAL INFECTIONS IN CIRRHOSISГавриленкоД. И.GavrilenkoD. I.noemail@neicon.ruГомельский государственный медицинский университетGomel State Medical University201128092011034450Copyright © Гавриленко Д.И., 20112011Гавриленко Д.И.Gavrilenko D.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/1125

Бактериальные инфекции являются частым и тяжелым осложнением цирроза печени и развиваются у 15-35 % госпитализированных пациентов. Среди наиболее частых инфекций - спонтанный бактериальный перитонит, мочевая инфекция, пневмония и бактериемия. Больные циррозом имеют разнообразные предрасполагающие механизмы, такие как изменения ретикулоэндотелиальной системы, снижение опсонизирующей активности асцитической жидкости, дисфункция нейтрофилов. Более 25 % случаев смерти среди пациентов с циррозом печени связаны с бактериальными инфекциями. Цель этой статьи - краткий обзор эпидемиологии, патогенеза, лечения, профилактики бактериальных инфекций при циррозе печени.

Bacterial infections are a frequent and severe complication of cirrhosis that may present on admission or develop during hospitalization in 15-35 % of hospitalized cirrhotic patients. The most frequent infective complications include spontaneous bacterial peritonitis, urinary tract infections, pneumonia and bacteremia. Patients with cirrhosis have of various facilitating mechanisms such as changes in the reticuloendothelial system, decreased opsonic activity of the ascitic fluid, neutrophil leukocyte dysfunction. Up to 25 % of cases of death in cirrhotic patients are related to bacterial infections. This article aims to provide a brief overview of the epidemiology, pathogenesis, treatment and prophylaxis of bacterial infection in cirrhosis.

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The authors declare that there are no conflicts of interest present.