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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2011-8-2-13</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1097</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>ОСОБЕННОСТИ МЕСТНОГО ИММУНИТЕТА У ПАЦИЕНТОВ С РАКОМ ПРЯМОЙ КИШКИ ПОСЛЕ РАДИКАЛЬНОГО ЛЕЧЕНИЯ</article-title><trans-title-group xml:lang="en"><trans-title>FEATURES OF LOCAL IMMUNITY IN PATIENTS WITH RECTAL CANCER AFTER RADICAL TREATMENT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Надыров</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nadyrov</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Угольник</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ugolnik</surname><given-names>T. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ачинович</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Achinovich</surname><given-names>S. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чубуков</surname><given-names>Ж. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chubukov</surname><given-names>Zh. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чубукова</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Chubukova</surname><given-names>T. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Республиканский научно-практический центр радиационной медицины и экологии человека</institution></aff><aff xml:lang="en"><institution>Republican Research Center for Radiation Medicine and Human Ecology</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Гомельский областной клинический онкологический диспансер</institution></aff><aff xml:lang="en"><institution>Gomel Regional Clinical Oncologic Dispensary</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2011</year></pub-date><volume>0</volume><issue>2</issue><fpage>69</fpage><lpage>73</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Надыров Э.А., Угольник Т.С., Ачинович С.Л., Чубуков Ж.А., Чубукова Т.Н., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Надыров Э.А., Угольник Т.С., Ачинович С.Л., Чубуков Ж.А., Чубукова Т.Н.</copyright-holder><copyright-holder xml:lang="en">Nadyrov E.A., Ugolnik T.S., Achinovich S.L., Chubukov Z.A., Chubukova T.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1097">https://journal.gsmu.by/jour/article/view/1097</self-uri><trans-abstract xml:lang="en"><p>Rectal cancer is one of the topical problems of modern oncology. The analysis of the differences in clinical, morphological and histochemical indicators in the groups of patients from Gomel region, which underwent different types of treatment for cancer of the rectum I-III stages has been carried out. A number of indicators revealed statistically significant differences. The survival analysis in the investigated groups was performed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак прямой кишки</kwd><kwd>иммуногистохимические прогностические факторы</kwd><kwd>выживаемость</kwd><kwd>rectal cancer</kwd><kwd>immunohistochemical prognostic factors</kwd><kwd>survival analysis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Злокачественные новообразования в Беларуси 2000-2009 / С. М. Поляков [и др.]; под ред. М. М. Сачек, А. И. Ларионова. - Минск: РНПЦ МТ, 2010. - 205 с.</mixed-citation><mixed-citation xml:lang="en">Злокачественные новообразования в Беларуси 2000-2009 / С. М. Поляков [и др.]; под ред. М. М. Сачек, А. И. Ларионова. - Минск: РНПЦ МТ, 2010. - 205 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Prognostic significance of CD8+ T-cell and macrophage peritumoral infiltration in colorectal cancer / Y. Funada [et al.] // Oncol.Rep. - 2003. - Vol. 10. - P. 309-313.</mixed-citation><mixed-citation xml:lang="en">Prognostic significance of CD8+ T-cell and macrophage peritumoral infiltration in colorectal cancer / Y. Funada [et al.] // Oncol.Rep. - 2003. - Vol. 10. - P. 309-313.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Intratumoral macrophage counts correlate with tumor progression in colorectal cancer / J. C. Kang [et al.] // J.Surg. Oncol. - 2010. - Vol. 102. - P. 242-248.</mixed-citation><mixed-citation xml:lang="en">Intratumoral macrophage counts correlate with tumor progression in colorectal cancer / J. C. Kang [et al.] // J.Surg. Oncol. - 2010. - Vol. 102. - P. 242-248.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Maksimovic, S. Laboratory-immunology indicators according as prognostic factors of patients with colon and rectum cancer / S. Maksimovic // Med. Arch. - 2005. - Vol. 59. - P. 7-10.</mixed-citation><mixed-citation xml:lang="en">Maksimovic, S. Laboratory-immunology indicators according as prognostic factors of patients with colon and rectum cancer / S. Maksimovic // Med. Arch. - 2005. - Vol. 59. - P. 7-10.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Прогностическое значение маркеров пролиферативной активности и апоптоза при аденоматозном полипозе и колоректальном раке / О. Н. Касьяненко [и др.] // Сахаровские чтения 2008 г.: экологические проблемы XXI в.: Материалы 8-й междунар. науч. конф., Минск, 22-23 мая 2008 г. / под ред. С. П. Кундаса, С. Б. Мельнова, С. С. Позняка. - Минск: МГЭУ им А. Д. Сахарова, 2008. - С. 63.</mixed-citation><mixed-citation xml:lang="en">Прогностическое значение маркеров пролиферативной активности и апоптоза при аденоматозном полипозе и колоректальном раке / О. Н. Касьяненко [и др.] // Сахаровские чтения 2008 г.: экологические проблемы XXI в.: Материалы 8-й междунар. науч. конф., Минск, 22-23 мая 2008 г. / под ред. С. П. Кундаса, С. Б. Мельнова, С. С. Позняка. - Минск: МГЭУ им А. Д. Сахарова, 2008. - С. 63.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Олейник, Е. К. Динамика экспрессии маркеров активации лимфоцитов больных с опухолями желудочно-кишечного тракта на различных стадиях заболевания / Е. К. Олейник, М. И. Шибаев, В. М. Олейник // Вопр. онкол. - 2005. - Т. 51, № 5. - С. 571-574</mixed-citation><mixed-citation xml:lang="en">Олейник, Е. К. Динамика экспрессии маркеров активации лимфоцитов больных с опухолями желудочно-кишечного тракта на различных стадиях заболевания / Е. К. Олейник, М. И. Шибаев, В. М. Олейник // Вопр. онкол. - 2005. - Т. 51, № 5. - С. 571-574</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Association of microvessel density and blood vessel invasion with the prognosis in rectal carcinoma at stages I to II / Y. J. Zhou [et al.] // Zhonghua Wei Chang Wai Ke Za Zhi. - 2010. - Vol. 13. - P. 516-519.</mixed-citation><mixed-citation xml:lang="en">Association of microvessel density and blood vessel invasion with the prognosis in rectal carcinoma at stages I to II / Y. J. Zhou [et al.] // Zhonghua Wei Chang Wai Ke Za Zhi. - 2010. - Vol. 13. - P. 516-519.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">The radiation-induced changes in rectal mucosa: hyperfractionated vs. hypofractionated preoperative radiation for rectal cancer / J. J. Starzewski [et al.] // Int. J. Radiat. Oncol. Biol.Phys. - 2006. - Vol. 64. - P. 717-724.</mixed-citation><mixed-citation xml:lang="en">The radiation-induced changes in rectal mucosa: hyperfractionated vs. hypofractionated preoperative radiation for rectal cancer / J. J. Starzewski [et al.] // Int. J. Radiat. Oncol. Biol.Phys. - 2006. - Vol. 64. - P. 717-724.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
