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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2011-8-1-10</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1063</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>К ВОПРОСУ ОБ ЭМПИРИЧЕСКОЙ АНТИБИОТИКОТЕРАПИИ ПРИ ТРОФИЧЕСКИХ ПОРАЖЕНИЯХ ПРИ РАЗЛИЧНЫХ ЗАБОЛЕВАНИЯХ СОСУДОВ</article-title><trans-title-group xml:lang="en"><trans-title>TO THE QUESTION OF EMPIRIC ANTIBIOTIC THERAP OF TROPHIC LESIONS IN VARIOUS VASCULAR DISEASES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лызиков</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyzikov</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осипов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Osipov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лызикова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyzikova</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Гомельский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Gomel State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2011</year></pub-date><volume>0</volume><issue>1</issue><fpage>58</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лызиков А.А., Осипов В.А., Лызикова Т.В., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Лызиков А.А., Осипов В.А., Лызикова Т.В.</copyright-holder><copyright-holder xml:lang="en">Lyzikov A.A., Osipov V.A., Lyzikova T.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1063">https://journal.gsmu.by/jour/article/view/1063</self-uri><abstract><p>Были проанализированы 126 результатов бактериологических исследований, проведенных в отделении хирургии сосудов Гомельского областного клинического кардиологического диспансера за период 2006-2007 гг. Staphylococcus aureus является наиболее распространенным (от 33,3 до 66,7 %) инфекционным агентом во всех группах обследуемых пациентов. Pseudomonas aeruginosa чаще выделялась в группах пациентов с облитерирующим атеросклерозом и постфлебитическим синдромом (15,4 и 19,3 % соответственно) и значительно реже - в группе трофических нарушений при варикозном расширении вен (4,8 %). Streptococcus epidermidis чаще выделялся у пациентов с облитерирующим атеросклерозом и варикозным расширением вен (ВРВ) (7,7 и 10,5 % соответственно), а Staphylococcus saprophyticus - у пациентов с облитерирующим атеросклерозом (11,5 %). Проведенный анализ позволяет считать наиболее оправданным применение ципрофлоксацина и гентамицина для эмпирической антибиотикотерапии всех вышеуказанных заболеваний на первичном этапе лечения.</p></abstract><trans-abstract xml:lang="en"><p>The results of 126 bacteriological investigations performed at the Department of vascular surgery, Gomel Regional Cardiologic Dispensary in the period from 2006 to 2007 have been analysed. In all the groups of the examined patients Staphylococcus aureus was the most widespread (33,3-66,7 %) infectious agent. Pseudomonas aeruginosa was most common for the patients suffering from PAD and postphlebitic syndrome (15,4 and 19,3 %, correspondingly) and significantly less prevalent in the group with trophic lesions in varix dilatation (4,8 %). Streptococcus epidermidis was most often revealed in the patients with PAD and varix dilatation (7,7 and 10,5 % correspondingly), аnd Staphylococcus saprophyticus - in the patients with PAD (11,5 %). The carried out analysis provides the ground to consider the application of ciprofloxacin and gentamicin in the initial treatment for all the above listed diseases as the most reasonable.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трофическая язва</kwd><kwd>бактериальное обсеменение</kwd><kwd>антибиотик</kwd><kwd>чувствительность</kwd><kwd>патология сосудов</kwd><kwd>trophic ulcer</kwd><kwd>bacterial seeding</kwd><kwd>antibiotics</kwd><kwd>sensitivity</kwd><kwd>vascular diseases</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ципринол (ципрофлоксацин): клиническое значение при лечении раневой инфекции / В. П. Яковлев [и др.] / Ципринол: Шаг вперед в противомикробной терапии. - М., 1992. - С. 27-31.</mixed-citation><mixed-citation xml:lang="en">Ципринол (ципрофлоксацин): клиническое значение при лечении раневой инфекции / В. П. 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