zdorПроблемы здоровья и экологииHealth and Ecology Issues2220-09672708-6011Gomel State Medical University10.51523/2708-6011.2011-8-1-3zdor-1056Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEОСТРЫЙ КОРОНАРНЫЙ СИНДРОМ: СОВРЕМЕННЫЕ ВОЗМОЖНОСТИ ТЕРАПИИ (обзор литературы, часть IV)THE ACUTE CORONARY SYNDROME: POSSIBILITY UP-TO-DATE POTENTIAL OF THE THERAPY (literature review. Part IV)СаливончикД. П.SalivonchikD. P.noemail@neicon.ruГомельский областной клинический кардиологический диспансерGomel Regional Clinical Cardiologic Dispensary201128032011012026Copyright © Саливончик Д.П., 20112011Саливончик Д.П.Salivonchik D.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.gsmu.by/jour/article/view/1056

В обзоре представлена информация о современной медикаментозной и инструментальной терапии острого коронарного синдрома (ОКС).

The information about the modern medical treatment of the acute coronary syndrome was presented in the this review.

острый коронарный синдроминфаркт миокарданестабильная стенокардияacute coronary syndromemyocardial infarctionunstable anginaReferencesThe SHOCK Trial Study Group Should we emergently revascularize Occluded Coronaries for cardiogenic shock: an international randomized trial of emergency PTCA/CABS-trial design / J. S. Hochman [et al.] // Am. Heart J. - 1999. - Vol. 137. - P. 313-321.The SHOCK Trial Study Group Should we emergently revascularize Occluded Coronaries for cardiogenic shock: an international randomized trial of emergency PTCA/CABS-trial design / J. S. Hochman [et al.] // Am. Heart J. - 1999. - Vol. 137. - P. 313-321.A prospective randomized comparison between paclitaxel and sirolimus stents in the real world of interventional cardiology: the TAXi trial / J. J. Goy [et al.] / J. Am. Coll. Cardiol. - 2005. - Vol. 18(45). - P. 308-311.A prospective randomized comparison between paclitaxel and sirolimus stents in the real world of interventional cardiology: the TAXi trial / J. J. Goy [et al.] / J. Am. Coll. Cardiol. - 2005. - Vol. 18(45). - P. 308-311.In-hospital and nine-month outcome of treatment of coronary bifurcational lesions with sirolimus-eluting stent / L. Ge [et al.] / J. Am. Coll. Cardiol. - 2005. - Vol. 95(6). - P. 757-760.In-hospital and nine-month outcome of treatment of coronary bifurcational lesions with sirolimus-eluting stent / L. Ge [et al.] / J. Am. Coll. Cardiol. - 2005. - Vol. 95(6). - P. 757-760.Nordmann, A. J. Mortality in randomized controlled trials comparing drug-eluting vs. bare metal stents in coronary artery disease: a meta-analysis / A. J. Nordmann, M. Briel, H. C. Bucher // Eur. Heart J. - 2006. - Vol. 27. - P. 2784-2814.Nordmann, A. J. Mortality in randomized controlled trials comparing drug-eluting vs. bare metal stents in coronary artery disease: a meta-analysis / A. J. Nordmann, M. Briel, H. C. Bucher // Eur. Heart J. - 2006. - Vol. 27. - P. 2784-2814.Routine vs. selective invasive strategies in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trial / S. R. Mehta [et al.] // J.A.M.A. - 2005. - Vol. 293. - P. 2908-2917.Routine vs. selective invasive strategies in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trial / S. R. Mehta [et al.] // J.A.M.A. - 2005. - Vol. 293. - P. 2908-2917.Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents / G. W. Stone // N. Engl. J. Med. - 2007. - Vol. 356. - P. 998-1008.Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents / G. W. Stone // N. Engl. J. Med. - 2007. - Vol. 356. - P. 998-1008.Serruys, P. W. Coronary-artery stents / P. W. Serruys, M. J. B. Kutryk, A. T. L. Ong // N. Engl. J. Med. - 2006. - Vol. 354. - P. 483-495.Serruys, P. W. Coronary-artery stents / P. W. Serruys, M. J. B. Kutryk, A. T. L. Ong // N. Engl. J. Med. - 2006. - Vol. 354. - P. 483-495.Coronary syndromes following aspirin withdrawal: a special risk for late stent thrombosis / E. Ferrari [et al.] / J. Am. Cardiol. - 2005. - Vol. 45. - P. 456-459.Coronary syndromes following aspirin withdrawal: a special risk for late stent thrombosis / E. Ferrari [et al.] / J. Am. Cardiol. - 2005. - Vol. 45. - P. 456-459.Usefulness of tirofiban among patients treated without percutaneous coronary intervention (TIMI high risk patients in PRISM-PLUS) / D. A. Morrow [et al.] // Am. J. Cardiol. - 2004. - Vol. 359. - P. 774-776.Usefulness of tirofiban among patients treated without percutaneous coronary intervention (TIMI high risk patients in PRISM-PLUS) / D. A. Morrow [et al.] // Am. J. Cardiol. - 2004. - Vol. 359. - P. 774-776.Рекомендации Европейского Кардиологического общества по проведению перкутанных коронарных вмешательств / В. Г. Терентьев. - Киев, 2005. - 84 с.Рекомендации Европейского Кардиологического общества по проведению перкутанных коронарных вмешательств / В. Г. Терентьев. - Киев, 2005. - 84 с.Systematic review: the comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery / D. M. Bravata [et al.] // Ann. Intern. Med. - 2007. - Vol. 147. - P. 703-716.Systematic review: the comparative effectiveness of percutaneous coronary interventions and coronary artery bypass graft surgery / D. M. Bravata [et al.] // Ann. Intern. Med. - 2007. - Vol. 147. - P. 703-716.Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal / W. J. Cantor [et al.] // Catheter. Cardiovasc. Interv. - 2006. - Vol. 69. - P. 73-83.Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal / W. J. Cantor [et al.] // Catheter. Cardiovasc. Interv. - 2006. - Vol. 69. - P. 73-83.Trombolysis (PCAT)-2 Trialists` Collaboraive Group. Does Time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients / E. Boersma [et al.] // Eur. Heart J. - 2006. - Vol. 27. - P. 779-788.Trombolysis (PCAT)-2 Trialists` Collaboraive Group. Does Time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients / E. Boersma [et al.] // Eur. Heart J. - 2006. - Vol. 27. - P. 779-788.Сергеев, Г. А. Интервенционные и хирургические методы лечения больных с острым коронарным синдромом при множественном поражении коронарных артерий / Г. А. Сергеев, Л. Г. Гелис, Ю. П. Островский // Мед. панорама. - 2006. - № 11. - С. 17-19.Сергеев, Г. А. Интервенционные и хирургические методы лечения больных с острым коронарным синдромом при множественном поражении коронарных артерий / Г. А. Сергеев, Л. Г. Гелис, Ю. П. Островский // Мед. панорама. - 2006. - № 11. - С. 17-19.Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease / P. W. Serruys [et al.] // N. Engl. J. Med. - 2001. - Vol. 344. - P. 1117-1124.Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease / P. W. Serruys [et al.] // N. Engl. J. Med. - 2001. - Vol. 344. - P. 1117-1124.Effect of coronary artery bypass graft surgery on survival-overview of 10-year result from randomized trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration / S. Yusuf [et al.] // Lancet. - 1994. - Vol. 344. - P. 563-570.Effect of coronary artery bypass graft surgery on survival-overview of 10-year result from randomized trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration / S. Yusuf [et al.] // Lancet. - 1994. - Vol. 344. - P. 563-570.Long-term potency of internal mammary artery bypass grafts: relationship with preoperative severity of native coronary artery stenosis / A. Berger [et al.] // Circulation. - 2004. - Vol. 14. - P. 36-40.Long-term potency of internal mammary artery bypass grafts: relationship with preoperative severity of native coronary artery stenosis / A. Berger [et al.] // Circulation. - 2004. - Vol. 14. - P. 36-40.Arterial revascularization with the right gastroepiploic artery and internal mammary arteries in 300 patients / J. Grandjean [et al.] // J. Thor. Cardiov. Surg. - 1994. - Vol. 107. - P. 1309-1316.Arterial revascularization with the right gastroepiploic artery and internal mammary arteries in 300 patients / J. Grandjean [et al.] // J. Thor. Cardiov. Surg. - 1994. - Vol. 107. - P. 1309-1316.Stress test criteria used in the conservative arm of the FRISC-II trial underdetects surgical coronary artery disease when applied to patients in the VAHQWISH trial / A. Goyal [et al.] // J. Am. Coll. Cardiol. - 2002. - Vol. 39. - P. 1601-1607.Stress test criteria used in the conservative arm of the FRISC-II trial underdetects surgical coronary artery disease when applied to patients in the VAHQWISH trial / A. Goyal [et al.] // J. Am. Coll. Cardiol. - 2002. - Vol. 39. - P. 1601-1607.Coronary revascularization in diabetic patients - a comparison of the randomized and observation components of the Bypass Angioplasty Revascularization Investigation (BARI) / K. M. Detre [et al.] // Circulation. - 1999. - Vol. 99. - P. 633-640.Coronary revascularization in diabetic patients - a comparison of the randomized and observation components of the Bypass Angioplasty Revascularization Investigation (BARI) / K. M. Detre [et al.] // Circulation. - 1999. - Vol. 99. - P. 633-640.CABRI Trial Participants First-year results of CABRI (Coronary Angioplasty versus Bypass Revascularization Investigation) // Lancet. - 1995. - Vol. 346. - P. 1179-1184.CABRI Trial Participants First-year results of CABRI (Coronary Angioplasty versus Bypass Revascularization Investigation) // Lancet. - 1995. - Vol. 346. - P. 1179-1184.Percutaneous coronary intervention versus coronary artery bypass graft surgery for patients with medically refractory myocardial ischemia and risk factors for adverse outcomes with bypass: a multicenter, randomized trial Investigators of the Department of Veterans Affairs Cooperative Study № 385, the Angina With Extremely Serious Operative Evaluation (AWESOME) / D. A. Morrison [et al.] // J. Am. Coll. Cardiol. - 2001. - Vol. 38. - P. 143-149.Percutaneous coronary intervention versus coronary artery bypass graft surgery for patients with medically refractory myocardial ischemia and risk factors for adverse outcomes with bypass: a multicenter, randomized trial Investigators of the Department of Veterans Affairs Cooperative Study № 385, the Angina With Extremely Serious Operative Evaluation (AWESOME) / D. A. Morrison [et al.] // J. Am. Coll. Cardiol. - 2001. - Vol. 38. - P. 143-149.Long-term safety and efficacy of percutaneous coronary intervention with stenting and coronary artery disease: a meta-analysis with 5-year patients-level data from the ARTS, ERACI-II, MASS-II, and SoS trials / J. Daemen [et al.] // Circulation. - 2008. - Vol. 118. - P. 1146-1154.Long-term safety and efficacy of percutaneous coronary intervention with stenting and coronary artery disease: a meta-analysis with 5-year patients-level data from the ARTS, ERACI-II, MASS-II, and SoS trials / J. Daemen [et al.] // Circulation. - 2008. - Vol. 118. - P. 1146-1154.Randomized, controlled trial of coronary artery bypass surgery versus percutaneous coronary intervention in patients with multivessel coronary artery disease: six-year follow-up from the Stent or Surgery Trial (S0S) / J. Booth [et al.] // Circulation. - 2008. - Vol. 118. - P. 381-388.Randomized, controlled trial of coronary artery bypass surgery versus percutaneous coronary intervention in patients with multivessel coronary artery disease: six-year follow-up from the Stent or Surgery Trial (S0S) / J. Booth [et al.] // Circulation. - 2008. - Vol. 118. - P. 381-388.The medicine, angioplasty, or surgery study (MASS-II): a randomized, controlled clinical trial of three therapeutic strategies for multivessel coronary artery disease-one-year results / W. Hueb [et al.] // J. Am. Coll. Cardiol. - 2004. - Vol. 43. - P. 1743-1751.The medicine, angioplasty, or surgery study (MASS-II): a randomized, controlled clinical trial of three therapeutic strategies for multivessel coronary artery disease-one-year results / W. Hueb [et al.] // J. Am. Coll. Cardiol. - 2004. - Vol. 43. - P. 1743-1751.Does clopidogrel increase blood loss following coronary artery bypass surgery? / M. W. Chu [et al.] // Ann. Thorac. Surg. - 2004. - Vol. 78. - P. 1536-1541.Does clopidogrel increase blood loss following coronary artery bypass surgery? / M. W. Chu [et al.] // Ann. Thorac. Surg. - 2004. - Vol. 78. - P. 1536-1541.European Guidelines on cardiovascular disease prevention in clinical practice: executive summary / Eur. Heart J. - 2007. - Vol. 28. - P. 2375-2414.European Guidelines on cardiovascular disease prevention in clinical practice: executive summary / Eur. Heart J. - 2007. - Vol. 28. - P. 2375-2414.Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism / P. Poirier [et al.] // Circulation. - 2006. - Vol. 113. - P. 898-918.Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism / P. Poirier [et al.] // Circulation. - 2006. - Vol. 113. - P. 898-918.Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association / R. H. Eckel [at al.] // Circulation. - 2006. - Vol. 113. - P. 2943-2946.Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association / R. H. Eckel [at al.] // Circulation. - 2006. - Vol. 113. - P. 2943-2946.Long-Term Intervention with Pravastatin in Ischemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels / N. Engl. J. Med. - 1998. - Vol. 339. - P. 1349-1357.Long-Term Intervention with Pravastatin in Ischemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels / N. Engl. J. Med. - 1998. - Vol. 339. - P. 1349-1357.

The authors declare that there are no conflicts of interest present.