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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">zdor</journal-id><journal-title-group><journal-title xml:lang="ru">Проблемы здоровья и экологии</journal-title><trans-title-group xml:lang="en"><trans-title>Health and Ecology Issues</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-0967</issn><issn pub-type="epub">2708-6011</issn><publisher><publisher-name>Gomel State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.51523/2708-6011.2010-7-1s-23</article-id><article-id custom-type="elpub" pub-id-type="custom">zdor-1051</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Без раздела</subject></subj-group></article-categories><title-group><article-title>ВИРУС-АССОЦИИРОВАННЫЙ И ВИРУС-НЕГАТИВНЫЙ РАК ШЕЙКИ МАТКИ: КЛИНИЧЕСКИЕ ОСОБЕННОСТИ</article-title><trans-title-group xml:lang="en"><trans-title>VIRUS-ASSOCIATED AND VIRUS-NEGATIVE CERVICAL CARCINOMA: CLINICAL FEATURES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чуруксаева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Churksaeva</surname><given-names>O. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коломиец</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolomiets</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Видяева</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Vidyaeva</surname><given-names>I. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Уразова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Urazova</surname><given-names>L. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>E. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ онкологии Сибирского отделения Российской Академии медицинских наук</institution></aff><aff xml:lang="en"><institution>Scientific Research Centre of Oncology of the Siberian Department of the Russian Academy of Medical Sciences</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2010</year></pub-date><volume>0</volume><issue>1S</issue><fpage>62</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чуруксаева О.Н., Коломиец Л.А., Видяева И.Г., Уразова Л.Н., Никитина Е.Г., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Чуруксаева О.Н., Коломиец Л.А., Видяева И.Г., Уразова Л.Н., Никитина Е.Г.</copyright-holder><copyright-holder xml:lang="en">Churksaeva O.N., Kolomiets L.A., Vidyaeva I.G., Urazova L.N., Nikitina E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.gsmu.by/jour/article/view/1051">https://journal.gsmu.by/jour/article/view/1051</self-uri><abstract><p>У 78 больных раком шейки матки (РШМ), находившихся на лечении в НИИ онкологии, проведено исследование на наличие папилломавирусной инфекции онкотропных типов. Среди обследованных пациенток у 90 % обнаружена генитальная папилломавирусная инфекция. Выявлено, что у больных вирус-ассоциированным РШМ преобладают ранние стадии заболевания, при местно-распространенном раке шейки матки (МРРШМ) отмечается высокая вирусная нагрузка, имеет место более благоприятное течение заболевания по сравнению с вирус-негативным раком шейки матки.</p></abstract><trans-abstract xml:lang="en"><p>To determine the presence of HPV oncotropic types, 78 patients with cervical carcinoma, attending the Scientific Research Centre of Oncology, have been examined. Among the examined patients, 90% were diagnosed as positive for genital HPV infection. The study reveals, that the patients with virus-associated cervical carcinoma have more commonly early stages of the disease, in locally invasive cervical carcinoma high virus load becomes more pronounced, and a more favorable course of the disease in comparison with virus-negative cervical carcinoma takes place.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>шейки матки</kwd><kwd>папилломавирусная инфекция</kwd><kwd>cervical carcinoma</kwd><kwd>HPV infection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Давыдов, М. И. Заболеваемость злокачественными новообразованиями / М. И. Давыдов, Е. М. Аксель // Вестн. РАМН. - 2007. - Т. 18, № 2. - С. 52-89.</mixed-citation><mixed-citation xml:lang="en">Давыдов, М. И. Заболеваемость злокачественными новообразованиями / М. И. Давыдов, Е. М. Аксель // Вестн. 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